Occult hepatitis B virus infection in Southern African blacks with hepatocellular carcinoma

Journal of Gastroenterology and Hepatology (Australia)

Volumn 23, Issue 9, 2008, Pages 1426-1430

  Kew, Michael C ^a,b   Welschinger, Robert ^b   Viana, Raquel ^b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Hepatitis B virus DNA; Polymerase chain reaction; Pre core core antigen; Surface antigen

Indexed keywords

HEPATITIS B CORE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; VIRUS ANTIBODY; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; FEMALE; GENE AMPLIFICATION; HEPATITIS B; HUMAN; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; NEGRO; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SOUTH AFRICA;

EID: 49849093436     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05481.x     Document Type: Article

References (29)

1. Brechot C, Thiers V, Kremsdorf D, Nalpas B, Pol S, Paterlini-Brechot P. Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely 'occult'? Hepatology 2001 34 : 194 203.
2. Raimondo G. Occult hepatitis B virus infection and liver disease: fact or fiction? J. Hepatol. 2001 34 : 471 3.
3. Torbenson M, Thomas DL. Occult hepatitis B. Lancet Inf. Dis. 2002 2 : 479 86.
4. Marrero JA, Lok AAS. Occult hepatitis B virus infection in patients with hepatocellular carcinoma: innocent bystander, cofactor, or culprit? Gastroenterology 2004 126 : 347 9.
5. Jilg W, Sieger E, Zachoval R, Schlatzl H. Individuals with antibodies against hepatitis C core antigens as the only serological marker for hepatitis B infection: high percentage of carriers of hepatitis B and C virus. J. Hepatol. 1995 23 : 15 20.
6. Koike K, Kobayashi M, Gondo M, Hayashi I, Osuga T, Takada S. Hepatitis B virus DNA is frequently found in liver biopsy samples from hepatitis C virus-infected chronic hepatitis patients. J. Med. Virol. 1998 54 : 249 55.
7. Cacciola I, Pollicino T, Sqadrito G, Cerenzia G, Orlando ME, Raimondo G. Occult hepatitis B virus infection in patients with chronic hepatitis C virus infection. N Engl. J. Med. 1999 341 : 22 6.
8. Kazemi-Shirazi L, Petermann D, Muller C. Hepatitis B virus DNA in sera and liver tissue of HBsAg-negative patients with chronic hepatitis C. J. Hepatol. 2000 33 : 785 90.
9. De Maria N, Colantoni A, Friedlander L et al. The impact of previous HBV on the course of chronic hepatitis C. Am. J. Gastroenterol. 2000 95 : 3529 36.
10. Sagnelli E, Coppola N, Scolastico C, Mogavero AR, Filpinni P, Piccinino F. HCV genotype and silent HBV co-infection: two main risk factors for a more severe liver disease. J. Med. Virol. 2001 64 : 350 5.
11. Squadrito G, Pollicino G, Cacciola I et al. Occult hepatitis B virus infection is associated with the development of hepatocellular carcinoma in chronic hepatitis C patients. Cancer 2006 106 : 1326 30.
12. Shire NJ, Rouster SD, Rajicic N, Sherman KE. Occult hepatitis B in HIV-infected patients. J. Acquir. Immune. Defic. Syndr. 2004 36 : 869 75.
13. Mphahlele MJ, Lukhwareni A, Burnett RJ, Moropeng LM, Ngobeni JM. High risk of occult hepatitis B virus infection in HIV-positive patients from South Africa. J. Clin. Virol. 2006 35 : 14 20.
14. Shafritz DA, Shouval D, Sherman MI, Hadziyannis SJ, Kew MC. Assessment of hepatitis-B virus DNA integration state in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous biopsies and post mortem liver tissues. N. Engl. J. Med. 1981 305 : 1067 73.
15. Kew MC, Fujita Y, Takahashi H, Coppins A, Wands JR. Comparison between polyclonal and first and second generation monoclonal radioimmunoassays in the detection of hepatitis B surface antigen in patients with hepatocellular carcinoma. Hepatology 1986 6 : 636 9.
16. Paterlini P, Gerken G, Nakajima E et al. Polymerase chain reaction to detect hepatitis B virus DNA and RNA sequences in primary liver cancers from patients negative for hepatitis B surface antigen. N. Engl. J. Med. 1990 323 : 80 5.
17. Paterlini P, Gerfen G, Khemeny F et al. Primary liver cancer in HBsAg-negative patients: a study of HBV genome using the polymerase chain reaction. In : Hollinger FB, Lemon S, Margolis HS, eds. Viral Hepatitis and Liver Disease. Baltimore, MD : Williams and Wilkins, 1991 605 10.
18. Owiredu WKBA, Kramvis A, Kew MC. Hepatitis B virus DNA in serum of healthy black African adults positive for hepatitis B surface antibody alone: possible association with recombination between genotypes A and D. J. Med. Virol. 2001 64 : 441 54.
19. Mphahlele MJ, Moloto MJ. Detection of HBV-DNA in serologically-negative or 'silent' hepatitis B virus infections: viral or host factors? S. Afr. Med. J. 2002 92 : 613 15.
20. Kramvis A, Kew MC, Bukofzer S. Hepatitis B virus mutants in serum and liver tissue of southern African blacks with hepatocellular carcinoma. J. Hepatol. 1998 28 : 132 41.
21. Kwok S, Higuchi R. Avoiding false-positives with PCR. Nature 1989 339 : 237 8.
22. Weinberger KM, Wiedenmann E, Bohm S, Jilg W. Sensitive and accurate quantitation of hepatitis B virus DNA using a kinetic fluorescence detecting system (TaqMan PCR). J. Virol. Methods 2000 85 : 75 82.
23. Villa E, Grottola A, Buttafoco P et al. Evidence for hepatitis B virus infection in patients with chronic hepatitis C with and without serological markers of hepatitis B. Dig. Dis. Sci. 1995 40 : 8 13.
24. Takeuchi M, Fujimoto J Niwamoto H, Yamamoto Y, Okamoto E. Frequent detection of hepatitis B virus X gene DNA in hepatocellular carcinoma and adjacent liver tissue in hepatitis B antigen-negative patients. Dig. Dis. Sci. 1997 42 : 2264 9.
25. Koike K, Kobayasi M, Gondo M, Hayashi I, Osuga T, Takada S. Hepatitis B virus is frequently found in liver biopsy samples from hepatitis C virus chronic hepatitis patients. J. Med. Virol. 1998 54 : 249 55.
26. Pollicino T, Squadrito G, Cerenzia G et al. Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection. Gastroenterology 2004 126 : 102 10.
27. Kew MC. The possible etiologic role of the hepatitis-B virus in hepatocellular carcinoma: evidence from Southern Africa. In : Chisari FV, ed. Advances in Hepatitis Research. New York : Masson Publishing, 1984 203 15.
28. Nirei K, Taneko M, Moriyama M, Arakawa Y. The clinical features of chronic hepatitis C are not affected by the coexistence of hepatitis B virus DNA in patients negative for hepatitis B surface antigen. Intervirology. 2000 43 : 95 101.
29. Chemin I, Zoulim Z, Merle P et al. High incidence of hepatitis B virus infection among chronic hepatitis cases of unknown etiology. J. Hepatol. 2001 34 : 447 54.