Sex-specific interaction between APOE genotype and carbohydrate intake affects plasma HDL-C levels: The Strong Heart Family Study

Genes and Nutrition

Volumn 3, Issue 2, 2008, Pages 87-97

  Mosher, M J ^a,b   Lange, L A ^c   Howard, B V ^d   Lee, E T ^e   Best, L G ^f   Fabsitz, R R ^g   MacCluer, J W ^h   North, K E ⁱ  

^a WESTERN WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF KANSAS   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d MEDSTAR RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^f MISSOURI BREAKS INDUSTRIES RESEARCH INC   (United States)

^g NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^h SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

ⁱ IL   (United States)

Author keywords

APOE; Carbohydrate; HDL C; Interaction; Lipids

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; BODY MASS; CARBOHYDRATE INTAKE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PROTEIN CARBOHYDRATE INTERACTION; REVIEW; SEX DIFFERENCE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 49749136629     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-008-0075-4     Document Type: Review

References (82)

1. Astrup A (2001) Healthy lifestyles in Europe: Prevention of obesity and type II diabetes by diet and physical activity. Public Health Nutr 4(2B):499-515
2. Brown W (2007) High-density lipoprotein and transport of cholesterol and triglyceride in blood. J Clin Lipidol 1:7-19
3. Bruckert E (2006) Epidemiology of low HDL-cholesterol: Results of studies and surveys. Eur Heart J Suppl 8(Suppl F):F17-F22
4. Chan GKD, the ACPM Policy Committee (2002) Diet in the prevention and control of obesity, insulin resistance, and Type II diabetes, College of Preventive Medicine, Washington DC
5. Couture P, Archer WR, Lamarche B, Landry N, Deriaz O, Corneau L, Bergeron J, Bergeron N (2003) Influences of apolipoprotein E polymorphism on the response of plasma lipids to the ad libitum consumption of a high-carbohydrate diet compared with a high-monounsaturated fatty acid diet. Metabolism 52(11):1454-1459
6. Dagher G, Donne N, Klein C, Ferre P, Dugail I (2003) HDL-mediated cholesterol uptake and targeting to lipid droplets in adipocytes. J Lipid Res 44(10):1811-1820
7. Dallongeville J, Lussier-Cacan S, Davignon J (1992) Modulation of plasma triglyceride levels by apoE phenotype: A meta-analysis. J Lipid Res 33(4):447-454
8. Demarchi DA, Salzano FM, Altuna ME, Fiegenbaum M, Hill K, Hurtado AM, Tsunetto LT, Petzl-Erler ML, Hutz MH (2005) APOE polymorphism distribution among Native Americans and related populations. Ann Hum Biol 32(3):351-365
9. Dong LWK (1996) Human apolipoprotein E4 domain interaction. J Biol Chem 271(Aug 9):19053-19057
10. Eichner JE, Dunn ST, Perveen G, Thompson DM, Stewart KE, Stroehla BC (2002) Apolipoprotein E polymorphism and cardiovascular disease: A HuGE review. Am J Epidemiol 155(6):487-495
11. Farkas MH, Weisgraber KH, Shepherd VL, Linton MF, Fazio S, Swift LL (2004) The recycling of apolipoprotein E and its amino-terminal 22 kDa fragment: Evidence for multiple redundant pathways. J Lipid Res 45:1546-1554
12. Fazio SLM (2006) Editorial: Sorting out the complexities of reverse cholesterol transport: CETP polymorphism, HDL and coronary disease. J Clin Endocrinol Metab 91(90):3273-3275
13. Ferrieres J, Sing CF, Roy M, Davignon J, Lussier-Cacan S (1994) Apolipoprotein E polymorphism and heterozygous familial hypercholesterolemia. Sex-specific effects. Arterioscler Thromb 14(10):1553-1560
14. Ford ES, Liu S (2001) Glycemic index and serum high-density lipoprotein cholesterol concentration among us adults. Arch Intern Med 161(4):572-6
15. Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502
16. Frikke-Schmidt R (2000) Context-dependent and invariant associations between APOE genotype and levels of lipoproteins and risk of ischemic heart disease: A review. Scand J Clin Lab Invest Suppl 233:3-25
17. Frikke-Schmidt R, Nordestgaard BG, Agerholm-Larsen B, Schnohr P, Tybjaerg-Hansen A (2000a) Context-dependent and invariant associations between lipids, lipoproteins, and apolipoproteins and apolipoprotein E genotype. J Lipid Res 41(11):1812-1822
18. Frikke-Schmidt R, Sing CF, Nordestgaard BG, Tybjaerg-Hansen A (2000b) Gender- and age-specific contributions of additional DNA sequence variation in the 5′ regulatory region of the APOE gene to prediction of measures of lipid metabolism. Hum Genet 115(4):331-345
19. Gamboa R, Vargas-Alarcon G, Medina-Urrutia A, Cardoso-Saldana G, Hernandez-Pacheco G, Zamora-Gonzalez J, Posadas-Romero C (2001) Influence of the apolipoprotein E polymorphism on plasma lipoproteins in a Mexican population. Hum Biol 73(6):835-843
20. Grundy SM (1998) Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome. Am J Cardiol 81(4A):18B-25B
21. Hallman DM, Boerwinkle E, Saha N, Sandholzer C, Menzel HJ, Csazar A, Utermann G (1991) The apolipoprotein E polymorphism: A comparison of allele frequencies and effects in nine populations. Am J Hum Genet 49(2):338-349
22. Hanley JA, Negassa A, Edwardes MD, Forrester JE (2003) Statistical analysis of correlated data using generalized estimating equations: An orientation. Am J Epidemiol 157(4):364-375
23. Havel PJ (2004) Update on adipocyte hormones: Regulation of energy balance and carbohydrate/lipid metabolism. Diabetes 53(Suppl 1):S143-S151
24. Heeren J, Beisiegel U, Grewal T (2006) Apolipoprotein E recycling: Implications for dyslipidemia and atherosclerosis. Arterioscler Thromb Vasc Biol 26:442-448
25. Hooper L, Summerbell CD, Higgins JP, Thompson RL, Capps NE, Smith GD, Riemersma RA, Ebrahim S (2001) Dietary fat intake and prevention of cardiovascular disease: Systematic review. BMJ 322(7289):757-763
26. Howard BV, Lee ET, Yeh JL, Go O, Fabsitz RR, Devereux RB, Welty TK (1996) Hypertension in adult American Indians. The Strong Heart Study. Hypertension 28(2):256-264
27. Howard BV, Van Horn L, Hsia J, Manson JE, Stefanick ML, Wassertheil-Smoller S, Kuller LH, LaCroix AZ, Langer RD, Lasser NL, Lewis CE, Limacher MC, Margolis KL, Mysiw WJ, Ockene JK, Parker LM, Perri MG, Phillips L, Prentice RL, Robbins J, Rossouw JE, Sarto GE, Schatz IJ, Snetselaar LG, Stevens VJ, Tinker LF, Trevisan M, Vitolins MZ, Anderson GL, Assaf AR, Bassford T, Beresford SA, Black HR, Brunner RL, Brzyski RG, Caan B, Chlebowski RT, Gass M, Granek I, Greenland P, Hays J, Heber D, Heiss G, Hendrix SL, Hubbell FA, Johnson KC, Kotchen JM (2006) Low-fat dietary pattern and risk of cardiovascular disease: The women's health initiative randomized controlled dietary modification trial. JAMA 295(6):655-666
28. Hu D, Jablonski KA, Sparling YH, Robbins DC, Lee ET, Welty TK, Howard BV (2002) Accuracy of lipoprotein lipids and apoproteins in predicting coronary heart disease in diabetic American Indians. The Strong Heart Study. Ann Epidemiol 12(2):79-85
29. Ikewaki K, Rader DJ, Zech LA, Brewer HB Jr (1994) In vivo metabolism of apolipoproteins A-I and E in patients with abetalipoproteinemia: implications for the roles of apolipoproteins B and E in HDL metabolism. J Lipid Res 35(10):1809-1819
30. Jones R (2003) Insulin resistance, diet and cardiovascular disease: A review. Food Agric Environ 1(1):26-29
31. Kamboh MI, Ferrell RE, Kottke B (1988) Genetic studies of human apolipoproteins. V. A novel rapid procedure to screen apolipoprotein E polymorphism. J Lipid Res 29(11):1535-1543
32. Kataoka S, Robbins DC, Cowan LD, Go O, Yeh JL, Devereux RB, Fabsitz RR, Lee ET, Welty TK, Howard BV (1996) Apolipoprotein E polymorphism in American Indians and its relation to plasma lipoproteins and diabetes. The Strong Heart Study. Arterioscler Thromb Vasc Biol 16(8):918-925
33. Kataoka SPM, Howard BV (1994) Simplified isoelectric focusing/ immunoblotting determination of Apoprotein E phenotype. Clin Chem 401(1):11-13
34. Kuczmarski RJ, Carroll MD, Flegal KM, Troiano RP (1997) Varying body mass index cutoff points to describe overweight prevalence among U.S. adults: NHANES III (1988-1994). Obes Res 5(6):542-548
35. Lahoz C, Schaefer EJ, Cupples LA, Wilson PW, Levy D, Osgood D, Parpos S, Pedro-Botet J, Daly JA, Ordovas JM (2001) Apolipoprotein E genotype and cardiovascular disease in the framingham heart study. Atherosclerosis 154(3):529-537
36. Lee E, Welty TK, Fabsitz R, Cowan LD, Le N, Oopik AJ, Cucchiara AJ, Savage PJ, Howard BV (1990) The Strong Heart Study: A study of cardiovascular disease in American Indians: Design and methods. Am J Epidemiol 132(6):1141-1155
37. Lee ET, Welty TK, Fabsitz R, Cowan LD, Ngoc-Anh LE, Oopik AJ, Cucchiara AJ, Savage PJ, Howard BV (1990) The Strong Heart Study. A study of cardiovascular disease in American Indians: Design and methods. Am J. Epidemiol 132:1141-1155
38. Lee RD, Nieman DC (1996) Nutritional assessment, Mosby
39. Lewis GF, Rader DJ (2005) New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ Res 96(12):1221-1232
40. Liese AD, Gilliard T, Schulz M, D'Agostino RB Jr, Wolever TM (2007) Carbohydrate nutrition, glycaemic load, and plasma lipids: The insulin resistance atherosclerosis study. Eur Heart J 28(1):80-87
41. Lorgeril D (1997) The "diet-heart" hypothesis in secondary prevention of coronary heart disease. Eur Heart J 18:13-18
42. Ma Y, Li Y, Chiriboga DE, Olendzki BC, Hebert JR, Li W, Leung K, Hafner AR, Ockene IS (2006) Association between carbohydrate intake and serum lipids. J Am Coll Nutr 25(2):155-163
43. Mahley RW, Innerarity TL, Rall SC Jr, Weisgraber KH (1984) Plasma lipoproteins: Apolipoprotein structure and function. J Lipid Res 25(12):1277-1294
44. Mahley RW, Pepin J, Palaoglu KE, Malloy MJ, Kane JP, Bersot TP (2000) Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype. J Lipid Res 41(8):1290-1301
45. Mann J, Skeaff M, and Truswell S (2001) Dietary fats and prevention of cardiovascular disease. Conclusion may have been underplayed. Bmj 323(7319):1000-1001; author reply 1001-1002
46. Mitchell BD, Gonzalez Villalpando C, Arredondo Perez B, Garcia MS, Valdez R, Stern MP (1995) Myocardial infarction and cardiovascular risk factors in Mexico City and San Antonio. Texas. Arterioscler Thromb Vasc Biol 15(6):721-725
47. Mittendorfer B (2005) Sexual dimorphism in human lipid metabolism. J Nutr 135(4):681-686
48. Moll PP (1993) Genetics of atherosclerosis: Some strategies for studies of apolipoprotein E. J Hum Biol 5:451-460
49. Mooradian AD, Haas MJ, Wong NC (2006) The effect of select nutrients on serum high-density lipoprotein cholesterol and apolipoprotein A-I levels. Endocr Rev 27(1):2-16
50. Mosher M (2002) Genetic architecture of plasma lipids in Siberian Buryat, In: Department of Anthropology, University of Kansas, Lawrence, KS, pp 174
51. Mosher MJ, Martin LJ, Cupples LA, Yang Q, Dyer TD, Williams JT, North KE (2005) Genotype-by-sex interaction in the regulation of high-density lipoprotein: The framingham heart study. Hum Biol 77(6):773-793
52. Nelson MR, Kardia SL, Ferrell RE, Sing CF (1999) Influence of apolipoprotein E genotype variation on the means, variances, and correlations of plasma lipids and apolipoproteins in children. Ann Hum Genet 63(Pt 4):311-328
53. NIH (1992) Triglyceride, high density lipoprotein, and coronary heart disease 10(2):1-28
54. North KE, Göring HH, Cole SA, Diego VP, Almasy L, Laston S, Cantu T, Howard BV, Lee ET, Best LG, Fabsitz RR, MacCleur JW (2006) Linkage analysis of LDL cholesterol in American Indian populations: The Strong Heart Family Study. J Lipid Res 47:59-66
55. North KE, Howard BV, Welty TK, Best LG, Lee ET, Yeh JL, Fabsitz RR, Roman MJ, MacCluer JW (2003) Genetic and environmental contributions to cardiovascular disease risk in American Indians: The strong heart family study. Am J Epidemiol 157(4):303-314
56. Ordovas JM (2004a) The quest for cardiovascular health in the genomic era: Nutrigenetics and plasma lipoproteins. Proc Nutr Soc 63(1):145-152
57. Ordovas JM, Mooser V (2002) The APOE locus and the pharmacogenetics of lipid response. Curr Opin Lipidol 13(2):113-117
58. Ordovas JM, Corella D (2004b) Genes, diet and plasma lipids: The evidence from observational studies, In: Ordovas A. P. S. a. J. M (ed) Nutrigenetics and Nutrigenomics, Karger, Basel, pp 41-76
59. Parks EJ, Krauss RM, Christiansen MP, Neese RA, Hellerstein MK (1999) Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance. J Clin Invest 104(8):1087-1096
60. Rader DJ (2006) Molecular regulation of HDL metabolism and function: implications for novel therapies. J Clin Invest 116(12):3090-3100
61. Rashid S, Patterson BW, Lewis GF (2006) Thematic review series: patient-oriented research. What have we learned about HDL metabolism from kinetics studies in humans? J Lipid Res 47(8):1631-1642
62. Ravnskov U (2002) A hypothesis out-of-date: The diet-heart idea. J Clin Epidemiol 55(11):1057-1063
63. Reilly M, Rader DJ (2006) Apolipoprotein E and coronary disease: A puzzling paradox. PLoS Med 3(6):e258
64. Reilly SL, Ferrell RE, Kottke BA, Kamboh MI, Sing CF (1991) The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on means and variances. Am J Hum Genet 49(6):1155-1166
65. Reilly SL, Kottke BA, Sing CF (1990) The effects of generation and gender on the joint distributions of lipid and apolipoprotein phenotypes in the population at large. J Clin Epidemiol 43(9):921-940
66. Ribalta J, Halkes CJ, Salazar J, Masana L, Cabezas MC (2005) Additive effects of the PPARgamma, APOE, and FABP-2 genes in increasing daylong triglycerides of normolipidemic women to concentrations comparable to those in men. Clin Chem 51(5):864-871
67. Schakel SF, Sievert YA, Buzzard IM (1988) Sources of data for developing and maintaining a nutrient database. J Am Diet Assoc 88(10):1268-1271
68. Schlierf G, Arab L, Oster P (1983) Influence of diet on high-density lipoproteins. Am J Cardiol 52(4):17B-19B
69. Schulz LO, Bennett PH, Ravussin E, Kidd JR, Kidd KK, Esparza J, Valencia ME (2006) Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U.S. Diabetes Care 29(8):1866-1871
70. Sing C, Davignon J (1985) Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am J Hum Genet 37(2):268-285
71. Sobel E, Papp JC, Lange K (2002) Detection and integration of genotyping errors in statistical genetics. Am J Hum Genet 70(2):496-508
72. Starc TJ, Shea S, Cohn LC, Mosca L, Gersony WM, Deckelbaum RJ (1998) Greater dietary intake of simple carbohydrate is associated with lower concentrations of high-density-lipoprotein cholesterol in hypercholesterolemic children. Am J Clin Nutr 67(6):1147-1154
73. Stengard JH, Clark AG, Weiss KM, Kardia S, Nickerson DA, Salomaa V, Ehnholm C, Boerwinkle E, Sing CF (2002) Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism. Am J Hum Genet 71(3):501-517
74. Stevens J, Gautman SP, Keil JE (1993) Body mass index and fat patterning as correlates of lipids and hypertension in an elderly, biracial population. J Gerontol 48(6):M249-M254
75. Sun L, Wilder K, McPeek MS (2002) Enhanced pedigree error detection. Hum Hered 54(2):99-110
76. Utermann G, Weisgraber KH, Weber W, Mahley RW (1984) Genetic polymorphism of apolipoprotein E: A variant form of apolipoprotein E2 distinguished by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J Lipid Res 25(4):378-382
77. Weinberg SL (2004) The diet-heart hypothesis: A critique. J Am Coll Cardiol 43(5):731-733
78. Willett WC (2002) Dietary fat plays a major role in obesity: No. Obes Rev 3:59-68
79. Woods SC, Gotoh K, Clegg DJ (2003) Gender differences in the control of energy homeostasis. Exp Biol Med (Maywood) 228(10):1175-1180
80. Yang EJ, Chung HK, Kim WY, Kerver JM, Song WO (2003) Carbohydrate intake is associated with diet quality and risk factors for cardiovascular disease in U.S. adults: NHANES III. J Am Coll Nutr 22(1):71-79
81. Yannakoulia M, Yiannakouris N, Bluher S, Matalas AL, Klimis-Zacas D, Mantzoros CS (2003) Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J Clin Endocrinol Metab 88(4):1730-1736
82. Zoico E, Di Francesco V, Mazzali G, Vettor R, Fantin F, Bissoli L, Guariento S, Bosello O, Zamboni M (2004) Adipocytokines, fat distribution, and insulin resistance in elderly men and women. J Gerontol A Biol Sci Med Sci 59(9):M935-M939