Administration of the calcineurin inhibitor cyclosporine modulates cocaine-induced locomotor activity in rats

Psychopharmacology

Volumn 200, Issue 1, 2008, Pages 129-139

  Addy, Nii A ^a   Bahi, Amine ^a   Taylor, Jane R ^a   Picciotto, Marina R ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Calcineurin; Cocaine; Locomotor activity; Nucleus accumbens; Sensitization; Synapsin

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; COCAINE; CYCLOSPORIN; CYCLOSPORIN A; DIMETHYL SULFOXIDE; DRUG VEHICLE; RAPAMYCIN; SODIUM CHLORIDE; SYNAPSIN I;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CHRONIC DRUG ADMINISTRATION; COCAINE DEPENDENCE; CONDITIONING; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG POTENTIATION; HABITUATION; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SENSITIZATION; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION;

ANIMALS; BEHAVIOR, ANIMAL; CALCINEURIN; COCAINE; CYCLOSPORINE; MALE; MOTOR ACTIVITY; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SYNAPSINS; TIME FACTORS;

EID: 49749105207     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-008-1189-5     Document Type: Article

References (52)

1. NA Addy EF Fornasiero TR Stevens JR Taylor MR Picciotto 2007 Role of calcineurin in nicotine-mediated locomotor sensitization J Neurosci 27 8571 8580
2. T Ahmed JU Frey 2005 Plasticity-specific phosphorylation of CaMKII, MAP-kinases and CREB during late-LTP in rat hippocampal slices in vitro Neuropharmacology 49 477 492
3. A Bahi F Boyer T Kafri J Dreyer 2004 CD81-induced behavioural changes during chronic cocaine administration: in vivo gene delivery with regulatable lentivirus Eur J Neurosci 19 1621 1633
4. M Bahler P Greengard 1987 Synapsin I bundles F-actin in a phosphorylation-dependent manner Nature 326 704 707
5. G Biala C Betancur I Mansuy B Giros 2005 The reinforcing effects of chronic D-amphetamine and morphine are impaired in a line of memory-deficient mice overexpressing calcineurin Eur J Neurosci 21 3089 3096
6. SL Borgland RC Malenka A Bonci 2004 Acute and chronic cocaine-induced potentiation of synaptic strength in the ventral tegmental area: electrophysiological and behavioral correlates in individual rats J Neurosci 24 7482 7490
7. CV Borlongan TB Freeman TA Scorcia KA Sherman WC Olanow DW Cahill PR Sanberg 1995 Cyclosporine-A increases spontaneous and dopamine agonist-induced locomotor behavior in normal rats Cell Transplant 4 65 73
8. DH Brunzell JR Chang B Schneider P Olausson JR Taylor MR Picciotto 2006 beta2 containing nicotinic acetylcholine receptors are involved in nicotine-induced increases in conditioned reinforcement but not progressive ratio responding for food in C57BL/6 mice. Psychopharmacology 184 328 338
9. S Cabib C Castellano V Cestari U Filibeck S Puglisi-Allegra 1991 D1 and D2 receptor antagonists differently affect cocaine-induced locomotor hyperactivity in the mouse Psychopharmacology (Berl) 105 335 339
10. WA Carlezon Jr J Thome VG Olson SB Lane-Ladd ES Brodkin N Hiroi RS Duman RL Neve EJ Nestler 1998 Regulation of cocaine reward by CREB Science 282 2272 2275
11. G Di Chiara A Imperato 1988 Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats Proc Natl Acad Sci USA 85 5274 5278
12. P Donatsch B Ryffel 1986 Pharmacokinetics of cyclosporine in toxicological studies Transplant Proc 18 71 76
13. J Dunn B Inderwies S Licata R Pierce 2005 Repeated administration of AMPA or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine Psychopharmacology 179 172 180
14. JD English JD Sweatt 1997 A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation J Biol Chem 272 19103 19106
15. A Ettenberg HO Pettit FE Bloom GF Koob 1982 Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems Psychopharmacology (Berl) 78 204 209
16. T Gerdjikov R Beninger 2005 Differential effects of calcineurin inhibition and protein kinase A activation on nucleus accumbens amphetamine-produced conditioned place preference in rats Eur J Neurosci 22 697 705
17. NE Goeders JE Smith 1983 Cortical dopaminergic involvement in cocaine reinforcement Science 221 773 775
18. P Greengard F Valtorta AJ Czernik F Benfenati 1993 Synaptic vesicle phosphoproteins and regulation of synaptic function Science 259 780 785
19. P Greengard P Allen A Nairn 1999 Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade Neuron 23 435 447
20. S Hilfiker F Benfenati F Doussau A Nairn A Czernik G Augustine P Greengard 2005 Structural domains involved in the regulation of transmitter release by synapsins J Neurosci 25 2658 2669
21. M Hotte S Thuault KT Dineley HC Hemmings Jr AC Nairn TM Jay 2007 Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo Synapse 61 24 28
22. X Hu K Ford F White 2005 Repeated cocaine administration decreases calcineurin (PP2B) but enhances DARPP-32 modulation of sodium currents in rat nucleus accumbens neurons Neuropsychopharmacology 30 916 926
23. WB Huttner W Schiebler P Greengard P De Camilli 1983 Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation J Cell Biol 96 1374 1388
24. 2+ stimulation of CREB-dependent transcription and ERK nuclear translocation Neuron 21 869 883
25. SI Iwata GH Hewlett ST Ferrell L Kantor ME Gnegy 1997 Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine J Pharmacol Exp Ther 283 1445 1452
26. 2+-dependent glutamate release in isolated nerve terminals J Neurosci 21 7944 7953
27. PW Kalivas JE Alesdatter 1993 Involvement of N-methyl-d-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine J Pharmacol Exp Ther 267 486 495
28. PW Kalivas P Duffy 1995 D1 receptors modulate glutamate transmission in the ventral tegmental area J Neurosci 15 5379 5388
29. PW Kalivas P Duffy 1998 Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area J Neurochem 70 1497 1502
30. R Karler LD Calder IA Chaudhry SA Turkanis 1989 Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801 Life Sci 45 599 606
31. R Kincaid C Balaban M Billingsley 1987 Differential localization of calmodulin-dependent enzymes in rat brain: evidence for selective expression of cyclic nucleotide phosphodiesterase in specific neurons Proc Natl Acad Sci USA 84 1118 1122
32. GF Koob 1992 Neural mechanisms of drug reinforcement Ann NY Acad Sci 654 171 191
33. J Liu J Farmer W Lane J Friedman I Weissman S Schreiber 1991 Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes Cell 66 807 815
34. QS Liu L Pu MM Poo 2005 Repeated cocaine exposure in vivo facilitates LTP induction in midbrain dopamine neurons Nature 437 1027 1031
35. BJ Mattson JM Bossert DE Simmons N Nozaki D Nagarkar JD Kreuter BT Hope 2005 Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A J Neurochem 95 1481 1494
36. AC McCreary CA Marsden 1993 Cocaine-induced behaviour: dopamine D1 receptor antagonism by SCH 23390 prevents expression of conditioned sensitisation following repeated administration of cocaine Neuropharmacology 32 387 391
37. MJ Miserendino EJ Nestler 1995 Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens Brain Res 674 299 306
38. RA Nichols TJ Chilcote AJ Czernik P Greengard 1992 Synapsin I regulates glutamate release from rat brain synaptosomes J Neurochem 58 783 785
39. A Nishi JA Bibb S Matsuyama M Hamada H Higashi AC Nairn P Greengard 2002 Regulation of DARPP-32 dephosphorylation at PKA-and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A J Neurochem 81 832 841
40. MS Reid K Hsu Jr SP Berger 1997 Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine Synapse 27 95 105
41. ME Reith MY Li QS Yan 1997 Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers Psychopharmacology (Berl) 134 309 317
42. MC Ritz RJ Lamb SR Goldberg MJ Kuhar 1987 Cocaine receptors on dopamine transporters are related to self-administration of cocaine Science 237 1219 1223
43. MC Ritz RJ Lamb SR Goldberg MJ Kuhar 1988 Cocaine self-administration appears to be mediated by dopamine uptake inhibition Prog Neuropsychopharmacol Biol Psychiatry 12 233 239
44. ZA Rodd-Henricks DL McKinzie TK Li JM Murphy WJ McBride 2002 Cocaine is self-administered into the shell but not the core of the nucleus accumbens of Wistar rats J Pharmacol Exp Ther 303 1216 1226
45. D Saal Y Dong A Bonci R Malenka 2003 Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons Neuron 37 577 582
46. DW Self LM Genova BT Hope WJ Barnhart JJ Spencer EJ Nestler 1998 Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior J Neurosci 18 1848 1859
47. P Svenningsson AC Nairn P Greengard 2005 DARPP-32 mediates the actions of multiple drugs of abuse Aaps J 7 E353 E360
48. RZ Terwilliger D Beitner-Johnson KA Sevarino SM Crain EJ Nestler 1991 A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function Brain Res 548 100 110
49. MA Ungless JL Whistler RC Malenka A Bonci 2001 Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons Nature 411 583 587
50. BJ Venton AT Seipel PE Phillips WC Wetsel D Gitler P Greengard GJ Augustine RM Wightman 2006 Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool J Neurosci 26 3206 3209
51. D Winder J Sweatt 2001 Roles of serine/threonine phosphatases in hippocampal synaptic plasticity Nat Rev Neurosci 2 461 474
52. D Yu J Luo F Bu W Zhang Q Wei 2006 Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain IUBMB Life 58 429 433