Persistence of tolerance to the anaesthetic effect of allopregnanolone in male rats

European Journal of Pharmacology

Volumn 592, Issue 1-3, 2008, Pages 73-80

  Türkmen, Şahruh ^a,b   Wahlström, Göran ^c   Bäckström, Torbjörn ^b   Johansson, Inga Maj ^b  

^a Sundsvall County Hospital   (Sweden)

^b UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

Allopregnanolone tolerance; Burst suppression threshold; GABAA receptor (Gamma aminobutyric acid A); In situ hybridisation; Neurosteroid

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; MESSENGER RNA; RECEPTOR SUBUNIT; UC 1009; UNCLASSIFIED DRUG;

ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG TOLERANCE; ELECTROENCEPHALOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN SITU HYBRIDIZATION; INFUSION PUMP; MALE; NEUROPHARMACOLOGY; NEUROTRANSMISSION; NONHUMAN; OPTIMAL DRUG DOSE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ADIPOSE TISSUE; ANALYSIS OF VARIANCE; ANESTHETICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ELECTROENCEPHALOGRAPHY; IN SITU HYBRIDIZATION; MALE; OLIGONUCLEOTIDES, ANTISENSE; PREGNANOLONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RNA, MESSENGER;

EID: 49749104236     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.07.001     Document Type: Article

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