-
1
-
-
0025217267
-
Ranolazine (RS-43285): A preliminary study of a new anti-anginal agent with selective effect on ischaemic myocardium
-
Jain D., Dasgupta P., Hughes LO, Lahiri A., Raftery EB Ranolazine (RS-43285): a preliminary study of a new anti-anginal agent with selective effect on ischaemic myocardium. Eur J Clin Pharmacol. 1990 ; 38: 111-114.
-
(1990)
Eur J Clin Pharmacol
, vol.38
, pp. 111-114
-
-
Jain, D.1
Dasgupta, P.2
Hughes, L.O.3
Lahiri, A.4
Raftery, E.B.5
-
2
-
-
0028016058
-
Double-blind efficacy and safety study of a novel anti-ischemic agent, ranolazine, versus placebo in patients with chronic stable angina
-
Thadani U., Ezekowitz M., Fenney L., Chiang Y. -K; for the Ranolazine Group. Double-blind efficacy and safety study of a novel anti-ischemic agent, ranolazine, versus placebo in patients with chronic stable angina. Circulation. 1994 ; 90: 726-734.
-
(1994)
Circulation
, vol.90
, pp. 726-734
-
-
Thadani, U.1
Ezekowitz, M.2
Fenney, L.3
Chiang, Y.4
The Ranolazine Group, F.5
-
3
-
-
12844280008
-
Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris
-
Rousseau MF, Pouleur H., Cocco G., Wolff AA Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris. Am J Cardiol. 2005 ; 95: 311-316.
-
(2005)
Am J Cardiol
, vol.95
, pp. 311-316
-
-
Rousseau, M.F.1
Pouleur, H.2
Cocco, G.3
Aa, W.4
-
4
-
-
0032983310
-
A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents
-
Pepine CJ, Wolffe AA ; for the Ranolazine Group. A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional antianginal agents. Am J Cardiol. 1999 ; 84: 46-50.
-
(1999)
Am J Cardiol
, vol.84
, pp. 46-50
-
-
Pepine, C.J.1
Aa, W.2
Group, R.3
-
5
-
-
11144356285
-
Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina
-
Chaitman BR, Skettino SL, Parker JO, et al.; for the MARISA Investigators. Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina. J Am Coll Cardiol. 2004 ; 43: 1375-1382.
-
(2004)
J Am Coll Cardiol
, vol.43
, pp. 1375-1382
-
-
Chaitman, B.R.1
Skettino, S.L.2
Parker, J.O.3
Investigators, M.4
-
6
-
-
0348129532
-
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. a randomized controlled trial
-
Chaitman BR, Pepine CJ, Parker JO, et al. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. A randomized controlled trial. JAMA. 2004 ; 291: 309-316.
-
(2004)
JAMA
, vol.291
, pp. 309-316
-
-
Chaitman, B.R.1
Pepine, C.J.2
Parker, J.O.3
-
7
-
-
33751214195
-
Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts
-
Fraser H., Belardinelli L., Wang L., Light PE, McVeigh JJ, Clanachan AS Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts. J Mol Cell Cardiol. 2006 ; 41: 1031-1038.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 1031-1038
-
-
Fraser, H.1
Belardinelli, L.2
Wang, L.3
Light, P.E.4
McVeigh, J.J.5
Clanachan, A.S.6
-
8
-
-
31644438932
-
The mechanism of ranolazine action to reduce ischemia-induced diastolic dysfunction
-
Belardinelli L., Shryock JC, Fraser H. The mechanism of ranolazine action to reduce ischemia-induced diastolic dysfunction. Eur Heart J. 2006 ; 8 (Suppl A). A10 - A13.
-
(2006)
Eur Heart J.
, vol.8
, Issue.SUPPL. A
-
-
Belardinelli, L.1
Shryock, J.C.2
Fraser, H.3
-
9
-
-
33947431938
-
A comparison between ranolazine and cvt-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion
-
Wang P., Fraser H., Lloyd SG, McVeigh JJ, Belardinelli L., Chatham JC A comparison between ranolazine and cvt-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion. J Pharmacol Exp Ther. 2007 ; 321: 213-220.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 213-220
-
-
Wang, P.1
Fraser, H.2
Lloyd, S.G.3
McVeigh, J.J.4
Belardinelli, L.5
Chatham, J.C.6
-
10
-
-
0028358143
-
Microvascular compression during myocardial ischemia: Mechanistic basis for no-reflow phenomenon
-
Manciet LH, Poole DC, McDonagh PF, Copeland JG, Mathieu-Costello O. Microvascular compression during myocardial ischemia: mechanistic basis for no-reflow phenomenon. Am J Physiol. 1994 ; 266: H1541 - H1550.
-
(1994)
Am J Physiol
, vol.266
-
-
Manciet, L.H.1
Poole, D.C.2
McDonagh, P.F.3
Copeland, J.G.4
Mathieu-Costello, O.5
-
11
-
-
0016315064
-
The "no-reflow" phenomenon following temporary coronary artery occlusion in the dog
-
Kloner RA, Ganote CE, Jennings RB The "no-reflow" phenomenon following temporary coronary artery occlusion in the dog. Clin Invest. 1974 ; 54: 1496-1508.
-
(1974)
Clin Invest.
, vol.54
, pp. 1496-1508
-
-
Kloner, R.A.1
Ganote, C.E.2
Jennings, R.B.3
-
12
-
-
33745266444
-
Improved left ventricular function and reduced necrosis after myocardial ischemia/reperfusion in rabbits treated with ranolazine, an inhibitor of the late sodium channel
-
Hale SL, Leeka JA, Kloner RA Improved left ventricular function and reduced necrosis after myocardial ischemia/reperfusion in rabbits treated with ranolazine, an inhibitor of the late sodium channel. J Pharmacol Exp Ther. 2006 ; 318: 418-423.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 418-423
-
-
Hale, S.L.1
Leeka, J.A.2
Kloner, R.A.3
-
13
-
-
0037663875
-
-
Bethesda, MD: National Institutes of Health;
-
Rasband WS Image J. Bethesda, MD: National Institutes of Health ; 1997-2007. http://rsb.info.nih.gov/ij/
-
(1997)
Image J
-
-
Rasband, W.S.1
-
14
-
-
0033603309
-
Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury
-
Imahashi K., Kusuoka H., Hashimoto K., Yoshioka J., Yamaguchi H., Nishimura T. Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury. Circ Res. 1999 ; 84: 1401-1406.
-
(1999)
Circ Res
, vol.84
, pp. 1401-1406
-
-
Imahashi, K.1
Kusuoka, H.2
Hashimoto, K.3
Yoshioka, J.4
Yamaguchi, H.5
Nishimura, T.6
-
15
-
-
0033603311
-
Sodium regulation during ischemia versus reperfusion and its role in injury
-
Murphy E., Cross H., Steenbergen C. Sodium regulation during ischemia versus reperfusion and its role in injury. Circ Res. 1999 ; 84: 1469-1470.
-
(1999)
Circ Res
, vol.84
, pp. 1469-1470
-
-
Murphy, E.1
Cross, H.2
Steenbergen, C.3
-
16
-
-
33745392178
-
Late sodium current in the pathophysiology of cardiovascular disease: Consequences of sodium-calcium overload
-
Noble D., Noble PJ Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload. Heart. 2006 ; 92: iv1 - iv5.
-
(2006)
Heart
, vol.92
-
-
Noble, D.1
Noble, P.J.2
-
17
-
-
0026666057
-
Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine
-
Undrovinas A., Fleidervish, Makielski JC Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine. Circ Res. 1992 ; 71: 1231-1241.
-
(1992)
Circ Res.
, vol.71
, pp. 1231-1241
-
-
Undrovinas, A.1
Fleidervish2
Makielski, J.C.3
-
18
-
-
0028325970
-
Palmitoyl carnitine modifies sodium currents and induces transient inward current in ventricular myocytes
-
Wu J., Corr PB Palmitoyl carnitine modifies sodium currents and induces transient inward current in ventricular myocytes. Am J Physiol. 1994 ; 266: H1034 - H1046
-
(1994)
Am J Physiol
, vol.266
-
-
Wu, J.1
Corr, P.B.2
-
19
-
-
0030957101
-
Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes
-
Ward CA, Giles WR Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes. J Physiol. 1997 ; 500 (Pt 3). 631-642.
-
(1997)
J Physiol
, vol.500
, Issue.3
, pp. 631-642
-
-
Ward, C.A.1
Giles, W.R.2
-
20
-
-
0024848058
-
Progressive impairment of regional myocardial perfusion after initial restoration of postischemic blood flow
-
Ambrosio G., Weisman HF, Mannisi JA, et al. Progressive impairment of regional myocardial perfusion after initial restoration of postischemic blood flow. Circulation. 1989 ; 80: 1846-1861.
-
(1989)
Circulation
, vol.80
, pp. 1846-1861
-
-
Ambrosio, G.1
Weisman, H.F.2
Mannisi, J.A.3
-
21
-
-
0036085066
-
Relationship between no reflow and infarct size as influenced by the duration of ischemia and reperfusion
-
Reffelmann T., Hale SL, Li G., et al. Relationship between no reflow and infarct size as influenced by the duration of ischemia and reperfusion. Am J Physiol. 2001 ; 282: H766 - H772.
-
(2001)
Am J Physiol
, vol.282
-
-
Reffelmann, T.1
Hale, S.L.2
Li, G.3
-
22
-
-
0025134189
-
Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion
-
Allely MC, Alps BJ Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion. Br J Pharmacol. 1990 ; 99: 5-6.
-
(1990)
Br J Pharmacol
, vol.99
, pp. 5-6
-
-
Allely, M.C.1
Alps, B.J.2
-
23
-
-
0035917675
-
Ranolazine, a partial fatty acid oxidation inhibitor, reduced myocardial infarct size and cardiac troponin T release in the rat
-
Zacharowski K., Blackburn B., Thiemermann C. Ranolazine, a partial fatty acid oxidation inhibitor, reduced myocardial infarct size and cardiac troponin T release in the rat. Eur J Pharmacol. 2001 ; 418: 105-110.
-
(2001)
Eur J Pharmacol
, vol.418
, pp. 105-110
-
-
Zacharowski, K.1
Blackburn, B.2
Thiemermann, C.3
-
24
-
-
0028657558
-
Effect of ranolazine on infarct size in a canine model of regional myocardial ischemia/reperfusion
-
Black SC, Gralinski MR, McCormack JG, Driscoll EM, Lucchesi BR Effect of ranolazine on infarct size in a canine model of regional myocardial ischemia/reperfusion. J Cardiovasc Pharmacol. 1994 ; 24: 921-928.
-
(1994)
J Cardiovasc Pharmacol
, vol.24
, pp. 921-928
-
-
Black, S.C.1
Gralinski, M.R.2
McCormack, J.G.3
Driscoll, E.M.4
Lucchesi, B.R.5
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