IGF1 is a modifier of disease risk in hereditary non-polyposis colorectal cancer

International Journal of Cancer

Volumn 123, Issue 6, 2008, Pages 1339-1343

  Reeves, Stuart G ^a   Rich, Dominique ^a   Meldrum, Cliff J ^b   Colyvas, Kim ^a   Kurzawski, Grzegorz ^c   Suchy, Janina ^c   Lubinski, Jan ^c   Scott, Rodney J ^a,b  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b JOHN HUNTER HOSPITAL   (Australia)

^c International Hereditary Cancer Center   (Poland)

Author keywords

Disease expression; HNPCC; IGF1 polymorphisms

Indexed keywords

DNA; SOMATOMEDIN BINDING PROTEIN 1;

ADOLESCENT; ADULT; AGED; ARTICLE; AUSTRALIA; COLORECTAL CANCER; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; DNA REPAIR; DNA SEQUENCE; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; HETEROZYGOSITY; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MISMATCH REPAIR; POLAND; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROPORTIONAL HAZARDS MODEL; REGRESSION ANALYSIS; STRUCTURAL GENE; SURVIVAL RATE; TANDEM REPEAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGE OF ONSET; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; KAPLAN-MEIERS ESTIMATE; MALE; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RISK FACTORS; SEX FACTORS;

EID: 49749090157     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23668     Document Type: Article

References (21)

1. De La Chapelle A. Genetic predisposition to colorectal cancer. Nat Rev Cancer 2003;4:769-80.
2. DeFrancisco J, Grady WM. Diagnosis and management of hereditary non-polyposis colon cancer. Gastrointest Endosc 2003;58:390-408.
3. Scott RJ, McPhillips M, Meldrum CJ, Fitzgerald PE, Adams K, Spigelman A, du Sart D, Tucker K, Kirk J. Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative families. Am J Hum Genet 2001;68:118-27.
4. De La Chapelle A. The incidence of Lynch syndrome. Fam Cancer 2005;4:233-7.
5. Talseth BA, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott RJ. Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53. Int J Cancer 2006;118:2479-84.
6. Jones JS, Chi X, Gu X, Lynch PM, Amos CI, Frazier ML. p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Clin Cancer Res 2004;10: 5845-9.
7. Zecevic M, Amos CI, Gu X, Campos IM, Jones JS, Lynch PM, Rodriguez-Bigas MA, Frazier ML. IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer. J Natl Cancer Inst 2006;98:139-43.
8. Reeves S, Meldrum C, Scott RJ. Re: IGF1 gene polymorphisms and risk for hereditary nonpolyposis colorectal cancer. J Natl Cancer Inst 2006;98:1664-5.
9. LeRoith D, Werner H, Beitner-Johnson D, Roberts CT. Molecular and cellular aspects of the insulin-like growth factor 1 receptor. Endocr Rev 1995;16:143-55.
10. Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr 2001;131:109S-120S.
11. Pollak MN, Schemhammer ES, Hankinson SE. Insulin-like growth factors and neoplasia. Nat Rev Cancer 2004;4:505-18.
12. Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilkinson P, Hennekens CH, Pollak M. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 1998;279:563-6.
13. Kaaks R. Nutrition, energy balance and colon cancer risk: the role of insulin and insulin like growth factor-I. IARC Sci Publ 2002;156:289-93.
14. Sandhu MS, Dunger DB, Giovannucci EL. Insulin, insulin-like growth factor-I (IGF-I). IGF binding proteins, their biologic interactions, and colorectal cancer. J Natl Cancer Inst 2002;94:972-80.
15. Rotwein P, Pollock KM, Didier DK, Krivi GG. Organization and sequence of the human insulin-like growth factor I gene. J Biol Chem 1986;261:4828-32.
16. Rosen CJ, Kurland ES, Vereault D, Adler RA, Rackoff PJ, Craig WY, Witte S, Rogers J, Bilezikian JP. Association between serum insulin growth factor-I (IGF-I) and a simple sequence repeat in IGF-I gene: implications for genetic studies of bone mineral density. J Clin Endocrinol Metab 1998;83:2286-90.
17. Tae HJ, Luo X, Kim KH. Roles of CCAAT/enhancer-binding protein and its binding site on repression and derepression of acetyl-CoA carboxylase gene. J Biol Chem 1994;269:10475-84.
18. Gebhardt F, Zanker KS, Brandt B. Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1. J Biol Chem 1999;274:13176-80.
19. Jemstrom H, Chu W, Vesprini D, Tao Y, Majeed N, Deal C, Pollak M, Narod SA. Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: implications for premenopausal breast cancer risk. Mol Genet Metab 2001;72:144-54.
20. Slattery ML, Samowitz W, Curtin K, Ma KN, Hoffman M, Caan B, Neuhausen S. Associations among IRS1, IRS2, IGF1, and, IGFBP3 genetic polymorphisms and colorectal cancer. Cancer Epidemiol Biomarkers Prev 2004;13:1206-14.
21. Wagner M, Hemminki K, Israelsson E, Grzybowska E, Soderberg M, Pamula J, Pekala W, Zientek H, Mielzynska D, Siwinska E, Försti A. Polymorphisms in the IGF1 and IGFBP3 promoter and the risk of breast cancer. Breast Cancer Res Treat 2005;92:133-40.