Donor HLA-C genotype has a profound impact on the clinical outcome following liver transplantation

American Journal of Transplantation

Volumn 8, Issue 9, 2008, Pages 1931-1941

  Hanvesakul, R ^a   Spencer, N ^c   Cook, M ^a   Gunson, B ^c   Hathaway, M ^d   Brown, R ^e   Nightingale, P ^b   Cockwell, P ^a,c   Hubscher, S G ^a,c   Adams, D H ^c   Moss, P ^c,f   Briggs, D ^d  

^a UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d NHS BLOOD AND TRANSPLANT   (United Kingdom)

^e BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^f Research Institute   (United Kingdom)

Author keywords

Chronic rejection; Graft cirrhosis; Graft survival; HLA C1 genotype; HLA C2 genotype; KIR; Liver transplantation; NK cells; Patient survival

Indexed keywords

HLA C ANTIGEN; IMMUNOGLOBULIN RECEPTOR; KILLER IMMUNOGLOBULIN LIKE RECEPTOR;

ADULT; ALLELE; ALLOGRAFT; ARTICLE; CHRONIC GRAFT REJECTION; COHORT ANALYSIS; CONFIDENCE INTERVAL; FEMALE; GENOTYPE; GRAFT FAILURE; HAZARD RATIO; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER CIRRHOSIS; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; ORGAN DONOR; PRIORITY JOURNAL; PROTEIN INTERACTION; STATISTICAL SIGNIFICANCE; SURVIVAL TIME; TREATMENT OUTCOME;

ADULT; ALLELES; COHORT STUDIES; FEMALE; FIBROSIS; FOLLOW-UP STUDIES; GENOTYPE; GRAFT REJECTION; GRAFT SURVIVAL; GREAT BRITAIN; HETEROZYGOTE; HISTOCOMPATIBILITY TESTING; HLA-C ANTIGENS; HOMOZYGOTE; HUMANS; INCIDENCE; KAPLAN-MEIERS ESTIMATE; KILLER CELLS, NATURAL; LIVER TRANSPLANTATION; MALE; MULTIVARIATE ANALYSIS; RECEPTORS, KIR; SURVIVAL ANALYSIS; TIME FACTORS; TISSUE DONORS; TREATMENT OUTCOME;

EID: 49649128828     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02341.x     Document Type: Article

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