Exercise training enhances in vivo tuberculosis purified protein derivative response in the elderly

Journal of Applied Physiology

Volumn 104, Issue 6, 2008, Pages 1690-1696

  Okutsu, Mitsuharu ^a   Yoshida, Yuko ^b   Zhang, Xiumin ^c   Tamagawa, Akira ^c   Ohkubo, Takayoshi ^d   Tsuji, Ichiro ^c   Nagatomi, Ryoichi ^c  

^a WASEDA UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

Delayed type hypersensitivity; Immunoglobulin G4; T helper 1 cells

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G4; TUBERCULIN;

AGED; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; EXERCISE; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; IN VIVO STUDY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SKIN MANIFESTATION; TH1 CELL; TH2 CELL; TUBERCULIN TEST; AGE; AGING; BLOOD; IMMUNOLOGY; INNATE IMMUNITY; LEUKOCYTE COUNT; MIDDLE AGED; PHYSIOLOGY; TIME;

AGE FACTORS; AGED; AGING; EXERCISE; FEMALE; HUMANS; IMMUNITY, NATURAL; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; LEUKOCYTE COUNT; MALE; MIDDLE AGED; TH1 CELLS; TH2 CELLS; TIME FACTORS; TUBERCULIN; TUBERCULIN TEST;

EID: 49649122313     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01044.2007     Document Type: Article

References (31)

1. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 392: 245-252, 1998.
2. Bonifacio E, Scirpoli M, Kredel K, Fuchtenbusch M, Ziegler AG. Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation. J Immunol 163: 525-532, 1999.
3. Boucher N, Dufeu-Duchesne T, Vicaut E, Farge D, Effros RB, Schachter F. CD28 expression in T cell aging and human longevity. Exp Gerontol 33: 267-282, 1998.
4. Cher DJ, Mosmann TR. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. J Immunol 138: 3688-3694, 1987.
5. Chin APMJ, de Jong N, Pallast EG, Kloek GC, Schouten EG, Kok FJ. Immunity in frail elderly: a randomized controlled trial of exercise and enriched foods. Med Sci Sports Exerc 32: 2005-2011, 2000.
6. Costanzo ES, Lutgendorf SK, Kohut ML, Nisly N, Rozeboom K, Spooner S, Benda J, McElhaney JE. Mood and cytokine response to influenza virus in older adults. J Gerontol A Biol Sci Med Sci 59: 1328-1333, 2004.
7. Ernst DN, Weigle O, Hobbs MV. Aging and lymphokine gene expression by T cell subsets. Nutr Rev 53: S18-S25; discussion S25-S26, 1995.
8. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 170: 2081-2095, 1989.
9. Flynn JL, Chan J. Immunology of tuberculosis. Annu Rev Immunol 19: 93-129, 2001.
10. Fong TA, Mosmann TR. The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones. J Immunol 143: 2887-2893, 1989.
11. Fujita K, Nagatomi R, Hozawa A, Ohkubo T, Sato K, Anzai Y, Sauvaget C, Watanabe Y, Tamagawa A, Tsuji I. Effects of exercise training on physical activity in older people: a randomized controlled trial. J Epidemiol 13: 120-126, 2003.
12. Ho CS, Lopez JA, Vuckovic S, Pyke CM, Hockey RL, Hart DN. Surgical and physical stress increases circulating blood dendritic cell counts independently of monocyte counts. Blood 98: 140-145, 2001.
13. Kaufmann SH. How can immunology contribute to the control of tuberculosis? Nat Rev Immunol 1: 20-30, 2001.
14. Keylock KT, Lowder T, Leifheit KA, Cook M, Mariani RA, Ross K, Kim K, Chapman-Novakofski K, McAuley E, Woods JA. Higher antibody, but not cell-mediated, responses to vaccination in high physically fit elderly. J Appl Physiol 102: 1090-1098, 2007.
15. Kohut ML, Cooper MM, Nickolaus MS, Russell DR, Cunnick JE. Exercise and psychosocial factors modulate immunity to influenza vaccine in elderly individuals. J Gerontol A Biol Sci Med Sci 57: M557-M562, 2002.
16. Lancaster GI, Halson SL, Khan Q, Drysdale P, Wallace F, Jeukendrup AE, Drayson MT, Gleeson M. Effects of acute exhaustive exercise and chronic exercise training on type 1 and type 2 T lymphocytes. Exerc Immunol Rev 10: 91-106, 2004.
17. Lundgren M, Persson U, Larsson P, Magnusson C, Smith CI, Hammarstrom L, Severinson E. Interleukin 4 induces synthesis of IgE and IgG4 in human B cells. Eur J Immunol 19: 1311-1315, 1989.
18. Ministry of Health, Labor and Welfare. Comprehensive. evaluation of tuberculosis. Ministry of Health, Labor and Welfare Database [Online], 2004, Tokyo, Japan. http://www.mhlw.go.jp/wp/seisaku/jigyou/04sougou/1-5-1html.
19. Mosmann T, Cherwinski HR, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136: 2348-2357, 1986.
20. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more [see comments]. Immunol Today 17: 138-146, 1996.
21. Nakayama K, Monma M, Fukushima T, Ohrui T, Sasaki H. Tuberculin responses and risk of pneumonia in immobile elderly patients. Thorax 55: 867-869, 2000.
22. Ng WY, Thai AC, Lui KF, Yeo PP, Cheah JS. Systemic levels of cytokines and GAD-specific autoantibodies isotypes in Chinese IDDM patients. Diabetes Res Clin Pract 43: 127-135, 1999.
23. Punnonen J, Aversa G, Cocks BG, McKenzie AN, Menon S, Zurawski G, de Waal Malefyt R, de Vries JE. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 90: 3730-3734, 1993.
24. Rentenaar RJ, Gamadia LE, van DerHoek N, van Diepen FN, Boom R, Weel JF, Wertheim-van Dillen PM, van Lier RA, ten Berge IJ. Development of virus-specific CD4(+) T cells during primary cytomegalovirus infection J Clin Invest 105: 541-548, 2000.
25. Skapenko A, Leipe J, Niesner U, Devriendt K, Beetz R, Radbruch A, Kalden JR, Lipsky PE, Schulze-Koops H. GATA-3 in human T cell helper type 2 development. J Exp Med 199: 423-428, 2004.
26. Smith TP, Kennedy SL, Fleshner M. Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men. J Appl Physiol 97: 491-498, 2004.
27. Sousa AO, Henry S, Maroja FM, Lee FK, Brum L, Singh M, Lagrange PH, Aucouturier P. IgG subclass distribution of antibody responses to protein and polysaccharide mycobacterial antigens in leprosy and tuberculosis patients. Clin Exp Immunol 111: 48-55, 1998.
28. Steensberg A, Toft AD, Bruunsgaard H, Sandmand M, Halkjaer-Kristensen J, Pedersen BK. Strenuous exercise decreases the percentage of type 1 T cells in the circulation. J Appl Physiol 91: 1708-1712, 2001.
29. Tsuji I, Tamagawa A, Nagatomi R, Irie N, Ohkubo T, Saito M, Fujita K, Ogawa K, Sauvaget C, Anzai Y, Hozawa A, Watanabe Y, Sato A, Ohmori H, Hisamichi S. Randomized controlled trial of exercise training for older people (Sendai Silver Center Trial; SSCT): study design and primary outcome. J Epidemiol 10: 55-64, 2000.
30. Widhe M, Ekerfelt C, Forsberg P, Bergstrom S, Ernerudh J. IgG subclasses in Lyme borreliosis: a study of specific IgG subclass distribution in an interferon-gamma-predominated disease. Scand J Immunol 47: 575-581, 1998.
31. Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89: 587-596, 1997.