Development of a human in vivo method to study the effect of ultraviolet radiation and sunscreens in melanocytic nevi

Dermatology

Volumn 217, Issue 2, 2008, Pages 124-136

  Carrera, Cristina ^a,f   Puig, Susana ^a,d   Llambrich, Alex ^a   Palou, Josep ^a,b   Lecha, Mario ^c   Massi, Daniela ^e   Malvehy, Josep ^a,d  

^a Melanoma Unit   (Spain)

^b Dermatopathology Unit   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e UNIVERSITY OF FLORENCE   (Italy)

^f INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Dermoscopy; Immunohistochemistry; Malignant melanoma; Melanocytes; Nevus; Photochemoprevention; Photoprotection; Sun exposure; Sunscreens; Ultraviolet radiation

Indexed keywords

AVOBENZONE; OCTOCRYLENE; SUNSCREEN; TITANIUM DIOXIDE;

ADULT; ARTICLE; CASE REPORT; CELL ACTIVATION; CELL PROLIFERATION; CHEMOPROPHYLAXIS; EPILUMINESCENCE MICROSCOPY; ERYTHEMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MALE; MELANOCYTE; MELANOCYTIC NEVUS; PRIORITY JOURNAL; RADIATION INJURY; RADIATION PROTECTION; RISK FACTOR; SKIN PROTECTION; ULTRAVIOLET B RADIATION; VALIDATION PROCESS;

BIOPSY, NEEDLE; DERMOSCOPY; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; NEVUS, PIGMENTED; RADIATION DOSAGE; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SKIN; SKIN NEOPLASMS; SKIN PIGMENTATION; SUNSCREENING AGENTS; ULTRAVIOLET RAYS;

EID: 49649107710     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000134612     Document Type: Article

References (40)

1. Bataille V: Genetic epidemiology of melanoma. Eur J Cancer 2003;39:1341-1347.
2. Bataille V, Winnett A, Sasieni P, Newton Bishop JA, Cuzick J: Exposure to the sun and sunbeds and the risk of cutaneous melanoma in the UK: a case-control study. Eur J Cancer 2004;40:429-435.
3. Rigel DS, Friedman RJ, Kopf AW: The incidence of malignant melanoma in the United States: issues as we approach the 21st century. J Am Acad Dermatol 1999;34:839-847.
4. Gilchrest B, Eller MS, Geller AC, Yaar M: The pathogenesis of melanoma induced by ultraviolet radiation. N Engl J Med 1999;340:1341-1348.
5. Naldi L, Imberti GL, Parazzini F, Gallus S, La Vecchia C: Pigmentary traits, modalities of sun reaction, history of sunburns, and melanocytic nevi as risk factors for cutaneous malignant melanoma in the Italian population. Cancer 2000;88:2703-2710.
6. Menzies S, Khalil M, Crotty K, Bonin A: The augmentation of melanocytic nevi in guinea pigs by solar-simulated light: an animal model for human melanocytic nevi. Cancer Res 1998;58:5361-5366.
7. Dulon M, Weichenthal M, Blettner M, Breitbart M, Hetzer M, Greinert R, et al: Sun exposure and number of nevi in 5- to 6-year-old European children. J Clin Epidemiol 2002;55:1075-1081.
8. Wachsmuth RC, Turner F, Barrett JH, Gaut R, Randerson-Moor JA, Bishop DT, Newton Bishop JA: The effect of sun exposure in determining nevus density in UK adolescent twins. J Invest Dermatol 2005;124:56-62.
9. Menzies SW, Greenoak GE, Abeywardana CM, Crotty KA, O'Neill ME: UV light from 290 to 325 nm, but not broad-band UVA or visible light augments the formation of melanocytic nevi in a guinea-pig model for human nevi. J Invest Dermatol 2004;123:354-360.
10. Ley RD: Animal models of ultraviolet (UVR)-induced cutaneous melanoma. Front Biosci 2002;1:1531-1534.
11. Wang SQ, Setlow R, Berwick M, Polsky D, Marghood AA, Kopf AW, Bart RS: Ultraviolet A and melanoma: a review. J Am Acad Dermatol 2001;44:837-846.
12. McHugh PJ, Spanswick VJ, Hartley JA: Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance. Lancet Oncol 2001;8:483-490.
13. Landi MT, et al: DNA repair, dysplastic nevi, and sunlight sensitivity in the development of cutaneous malignant melanoma. J Natl Cancer Inst 2002;94:94-101.
14. Hussein MR, Haemel AK, Wood GS: Apoptosis and melanoma: molecular mechanisms. J Pathol 2003;199:275-288.
15. Bykov VJ, Marcusson JA, Hemminki K: Ultraviolet B-induced DNA damage in human skin and its modulation by a sunscreen. Cancer Res 1998;58:2961-2964.
16. Dennis LK, Beane Freeman LE, Van Beek MJ: Sunscreen use and the risk for melanoma: a quantitative review. Ann Intern Med 2003;139:966-978.
17. Bauer J, Buttner P, Wiecker TS, Luther H, Garbe C: Effect of sunscreen and clothing on the number of melanocytic nevi in 1,812 German children attending day care. Am J Epidemiol 2005;161:620-627.
18. Harrison SL, Buettner PG, Maclennan R: The North Queensland 'Sun-Safe Clothing' study: design and baseline results of a randomized trial to determine the effectiveness of sun-protective clothing in preventing melanocytic nevi. Am J Epidemiol 2005;161:536-545.
19. Puig S, Ruiz A, Castel T, Volpini V, Malvehy J, Cardellach F, Lynch M, Mascaro JM, Estivill X: Inherited susceptibility to several cancers but absence of linkage between dysplastic nevus syndrome and CDKN2A in a melanoma family with a mutation in the CDKN2A (p16INK4A) gene. Hum Genet 1997;101:359-364.
20. Ruiz A, Puig S, Malvehy J, Lazaro C, Lynch M, Gimenez-Arnau AM, Puig L, Sanchez-Conejo J, Estivill X, Castel T: CDKN2A mutations in Spanish cutaneous malignant melanoma families and patients with multiple melanomas and other neoplasia. J Med Genet 1999;36:490-494.
21. Rizos H, Puig S, Badenas C, Malvehy J, Darmanian AP, Jiménez L, Milà M, Kefford RF: A melanoma-associated germline mutation in exon 1β inactivates p14ARF. Oncogene 2001;20:5543-5547.
22. Puig S, Malvehy J, Badenas C, Ruiz A, Jimenez D, Cuellar F, Azon A, Gonzalez U, Castel T, Campoy A, Herrero J, Marti R, Brunet-Vidal J, Mila M: Role of the CDKN2A locus in patients with multiple primary melanomas. J Clin Oncol 2005;23:3043-3051.
23. Serre I, Cano JP, Picol MC, Meynadier J, Meunier L: Immunosuppression induced by acute solar-simulated ultraviolet exposure in humans: prevention by a sunscreen with a sun protection factor of 15 and high UVA protection. J Am Acad Dermatol 1997;37:187-194.
24. Schiller M, Brzoska T, Böhm M, Metze D, et al: Solar-simulated ultraviolet radiation-induced upregulation of the melanocortin-1 receptor, proopiomelanocortin, and alpha-melanocyte-stimulating hormone in human epidermis in vivo. J Invest Dermatol 2004;122:468-476.
25. Holman CDJ, Heenan PJ, Caruso V, et al: Seasonal variation in the junctional component of pigmented naevi. Int J Cancer 1983;31:213-215.
26. Armstrong BK, Heenan PJ, Caruso V, et al: Seasonal variation in pigmented nevi. Int J Cancer 1984;34:441-442.
27. Larsen TE, Mogensen SB, Holme I: Seasonal variations of pigmented naevi: intercorrelations of clinical and histological variables with special reference to seasonal variation. Acta Derm Venereol 1990;70:115-120.
28. Pawlowski A, Pawlowski MD, Lea PJ: Effects of UV radiation on the ultrastructure of human common pigmented naevi and lentigines. Acta Derm Venereol 1991;71:113-117.
29. Tronnier M, Smolle J, Wolff HH: Ultraviolet irradiation induces acute changes in melanocytic nevi. J Invest Dermatol 1995;104:475-478.
30. Tronnier M, Wolff HH: UV-irradiated melanocytic naevi simulating melanoma in situ. Am J Dermatopathol 1995;17:1-6.
31. Stanganelli I, Rafanelli S, Bucchi L: Seasonal prevalence of digital epiluminescence microscopy patterns in acquired melanocytic nevi. J Am Acad Dermatol 1996;34:460-464.
32. Stanganelli I, Bauer P, Bucchi L, et al: Critical effects of intense sun exposure on the expression of epiluminescence microscopy features of acquired melanocytic nevi. Arch Dermatol 1997;133:979-982.
33. Hofmann-Wellenhof R, Wolf P, Smolle J, et al: Influence of UV-B therapy on dermoscopic features of acquired melanocytic nevi. J Am Acad Dermatol 1997;387:559-563.
34. Hofmann-Wellenhof R, Soyer P, Wolf IH, et al: Ultraviolet radiation of melanocytic nevi. Arch Dermatol 1998;134:845-850.
35. Tronnier M, Alexander M, Wolff HH: Adhesion molecule expression in normal skin and melanocytic lesions: role of UV-irradiation and architectural characteristics in nevi. J Cutan Pathol 1997;24:278-285.
36. Böni R, Matt D, Burg G. Tronnier M, Vortmeyer A, Zhuang Z: Ultraviolet-induced acute histological changes in irradiated nevi are not associated with allelic loss. Arch Dermatol 1998;134:853-856.
37. Rudolph P, et al: Enhanced expression of Ki-67, topoisomerase IIa, PCN, p53 and p21 reflecting proliferation and repair activity in UV-irradiated melanocytic nevi. Hum Pathol 1998;29:1480-1487.
38. Tronnier M, Alexander M, Neitmann M, Brinckmann J, Wolff HH: Morphological changes in melanocytic nevi induced by exogenous factors. Hautarzt 2000;51:561-566.
39. Krengel S, Alexander M, Brinckmann J, Tronnier M: MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light. J Cutan Pathol 2002;29:390-396.
40. Zalaudek I, Argenziano G, Di Stefani A, et al: Dermoscopy in general dermatology. Dermatology 2006;212:7-18.