Determination of ginsenosides content in Korean ginseng seeds and roots by high performance liquid chromatography

Food Science and Biotechnology

Volumn 17, Issue 2, 2008, Pages 430-433

  Jiang, Ning Hu ^a   Lee, Jeung Hee ^a   Jung, Ah Shin ^a   Jae, Eul Choi ^a   Lee, Ki Teak ^a  

^a Chungnam National University   (South Korea)

Author keywords

Ginseng seed; Ginsenoside content; Quantification; Root

Indexed keywords

PANAX GINSENG;

EID: 49649107494     PISSN: 12267708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. 1 and its mechanism of action. Acta Pharmacol. Sin. 2: 143-149 (2005)
2. Vuksan V, Sung MK, Sievenpiper JL, Stavro PM, Jenkins AL, Di Buono M, Lee KS, Leiter LA, Nam KY, Arnason JT, Choi M, Naeem A. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: Results of a randomized, double-blind, placebo-controlled study of efficacy and safety. Nutr. Metab. Cardiovas. 21: 1-11 (2006)
3. Surh YJ, Na HK, Lee JY, Keum YS. Molecular mechanisms underlying anti-tumor promoting activities of heat- processed Panax ginseng C.A. Meyer. J. Korean Med. Sci. 16: 38-41 (2001)
4. Rai D, Bhatia G, Sen T, Palit G. Anti-stress effects of Ginkgo biloba and Panax ginseng: A comparative study. J. Pharmacol. Sci. 4: 458-464 (2003)
5. Wang BX, Cui JC, Liu AJ, Wu SK. Studies on the anti-fatigue effect of the saponins of stems and leaves of Panax ginseng (SSLG). J. Tradit. Chin. Med. 2: 89-94 (1983)
6. Yoon YJ, Kim NY, Rhee YK, Han MJ. Quality characteristics and biological activities of traditionally fermented ginseng wine. Food Sci. Biotechnol. 16: 198-204 (2007)
7. Chan TW, But PP, Cheng SW. Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS. Anal. Chem. 72: 1281-1287 (2000)
8. Li WK, Gu CG, Zhang HJ, Awang DVC, Fitzloff JF, Fong HHS, Van Breeman RB. Use of high performance liquid chromatography tandem mass spectrometry to distinguish Panax ginseng C.A. Meyer (Asian ginseng) and Panax quinquefolius. L. (North American ginseng). Anal. Chem. 72: 5417-5422 (2000)
9. 1 on lipopolysaccaride-induced microcirculatory disturbance in rat mesentery. Life Sci. 81: 509-518 (2007)
10. Tsang D, Yeung HW, Tso WW, Peck H. Ginseng saponins: Influence on neurotransmitter uptake in rat brain synaptosomes. Planta. Med. 3: 221-224 (1985)
11. 1 on central cholinergic metabolism. Pharmacology 42: 223-229 (1991)
12. Yang ZY, Sun HX, Ye YP. Ginsenoside Rd from Panax notoginseng is cytotoxic towards Hela cancer cells and induces apoptosis. Chem. Biodivers. 3: 187-197 (2006)
13. 2 on the proliferation of prostate cancer cells. Arch. Pharm. Res. 27: 429-435 (2004)
14. 1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells. J. Steriod Biochem. 84: 463-468 (2003)
15. 2 Synergistically enhances paclitaxel or mitoxantrone in prostate cancer models. J. Urology 5: 1926-1931 (2006)
16. Shi W, Wang YT, Li J, Zhang HQ, Ding L. Investigation of ginsenosides in different parts and ages of Panax ginseng. Food Chem. 102: 664-668 (2007)
17. Joong HK, Jacqueline MR, Bélanger, JR, Jocelyn P, Varoujan AY. Application of the microwave-assisted process (MAPTM) to the fast extraction of ginseng saponins. Food Res. Int. 36: 491-498 (2003)
18. Han ST, Shin CG, Yang BW, Hahm YT, Sohn UD, Im BO, Cho SH, Lee BY, Ko SK. Analysis of ginsenoside composition of woods-grown ginseng roots. Food Sci. Biotechnol. 16: 281-284 (2007)
19. Kim SO, Park CW, Moon SY, Lee HA, Kim BK, Lee DU, Lee JH, Park JY. Effects of high-hydrostatic pressure on ginsenoside concentrations in Korean red ginseng. Food Sci. Biotechnol. 16: 848-853 (2007)
20. Ando T, Tanaka O, Shibata S. Chemical studies on the oriental plant drugs (XXV). Comparative studies on the saponins and sapogenins of ginseng and related crude drugs. Syoyakuga. Zasshi 25: 28-32 (1971)
21. Joo HK, Cho KS. Studies on the extracting methods of ginseng extract and saponins in Panax ginseng. J. Ginseng Sci. 3: 40-53 (1979)
22. Kwak YS, Kim MJ, Kim EH, Kim YA. A rapid extraction of ginseng saponin components. Korean J. Food Sci. Technol. 29: 1327-1329 (1995)
23. Kim SJ, Murthy HN, Hahn EJ, Lee HL, Paek KY. Parameters affecting the extraction of ginsenosides from the adventitious roots of ginseng (Panax ginseng C.A. Meyer). Sep. Purif. Technol. 56: 401-406 (2007)
24. Wu JY, Lin LD, Chau FT. Ultrasound-assisted extraction of ginseng saponins from ginseng roots and cultured ginseng cells. Ultrason. Sonochem. 8: 347-352 (2001)
25. Fuzzati N, Gabetta B, Jayakar K, Pace R, Ramaschi G, Villa F. Determination of ginsenosides in Panax ginseng roots by liquid chromatography with evaporative light-scattering detection. J. Assoc. Off. Ana. Chem. Int. 83: 820-829 (2000)
26. Attele AS, Zhou YP, Xie JT, Wu JA. Antidiabetic effects of Panax ginseng seeds extract and the identification of an effective component. Diabetes 51: 1851-1858 (2002)