Airway basement membrane perimeter distensibility and airway smooth muscle area in asthma

Journal of Applied Physiology

Volumn 104, Issue 6, 2008, Pages 1703-1708

  James, Alan L ^a,b   Green, Francis H ^c   Abramson, Michael J ^d   Bai, Tony R ^e   Dolhnikoff, Marisa ^f   Mauad, Thais ^f   McKay, Karen O ^g   Elliot, John G ^a  

^a PATHWEST LABORATORY MEDICINE   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF CALGARY   (Canada)

^d MONASH UNIVERSITY   (Australia)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f University Medical School   (Brazil)

^g CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

Author keywords

Lung inflation

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ASTHMA; BASEMENT MEMBRANE; BREATHING MUSCLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; LUNG INFLATION; LUNG PARENCHYMA; MALE; MUSCLE STRETCHING; PRIORITY JOURNAL; SMOOTH MUSCLE; THICKNESS; AGED; AUSTRALIA; BRAZIL; CANADA; CASE CONTROL STUDY; CHILD; CLINICAL TRIAL; LUNG; LUNG COMPLIANCE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; NEW ZEALAND; PATHOLOGY; PATHOPHYSIOLOGY;

ADOLESCENT; ADULT; AGED; ASTHMA; AUSTRALIA; BASEMENT MEMBRANE; BRAZIL; BRITISH COLUMBIA; CASE-CONTROL STUDIES; CHILD; FEMALE; HUMANS; LUNG; LUNG COMPLIANCE; MALE; MIDDLE AGED; MUSCLE, SMOOTH; NEW ZEALAND;

EID: 49649099264     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00169.2008     Document Type: Article

References (35)

1. Abramson MJ, Bailey MJ, Couper FJ, Driver JS, Drummer OH, Forbes AB, McNeil JJ, Walters EH. Are asthma medications and management related to deaths from asthma? Am J Respir Crit Care Med 163: 12-18, 2001.
2. Bai TR. Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus. Am Rev Respir Dis 143: 441-443, 1991.
3. Carroll ML, Carroll NG, James AL. Do bronchial biopsies represent mast cell density in airways? A stereological study. Eur Respir J 28: 612-621, 2006.
4. Carroll N, Carello S, Cooke C, James A. Airway structure and inflammatory cells in fatal attacks of asthma. Eur Respir J 9: 709-715, 1996.
5. Carroll N, Cooke C, James A. The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics. Eur Respir J 10: 292-300, 1997.
6. Carroll N, Elliot J, Morton A, James A. The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis 147: 405-410, 1993.
7. Dunnill MS, Massarella GR, Anderson JA. A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema. Thorax 24: 176-179, 1969.
8. Ebina M, Takahashi T, Chiba T, Motomiya M. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am Rev Respir Dis 148: 720-726, 1993.
9. Ebina M, Yaegashi H, Chiba R, Takahashi T, Motomiya M, Tanemura M. Hyperreactive site in the airway tree of asthmatic patients revealed by thickening of bronchial muscles. A morphometric study. Am Rev Respir Dis 141: 1327-1332, 1990.
10. Hessel PA, Mitchell I, Tough S, Green FH, Cockcroft D, Kepron W, Butt JC. Risk factors for death from asthma. Prairie Provinces Asthma Study Group. Ann Allergy Asthma Immunol 83: 362-368, 1999.
11. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, Pare PD. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350: 2645-2653, 2004.
12. Horsfield K, Cumming G. Morphology of the bronchial tree in man. J Appl Physiol 24: 373-383, 1968.
13. Horsfield K. Diameters, generations, and orders of branches in the bronchial tree. J Appl Physiol 68: 457-461, 1990.
14. Hossain S, Heard BE. Hyperplasia of bronchial muscle in chronic bronchitis. J Pathol 101: 171-184, 1970.
15. Huber HL, Koessler KK. The pathology of fatal asthma. Arch Intern Med 30: 689-760, 1922.
16. James AL, Hogg JC, Dunn LA, Pare PD. The use of the internal perimeter to compare airway size and to calculate smooth muscle shortening. Am Rev Respir Dis 138: 136-139, 1988.
17. James AL, Pare PD, Hogg JC. Effects of lung volume, bronchoconstriction, and cigarette smoke on morphometric airway dimensions. J Appl Physiol 64: 913-919, 1988.
18. James AL, Pare PD, Hogg JC. The mechanics of airway narrowing in asthma. Am Rev Respir Dis 139: 242-246, 1989.
19. James AL, Pare PD, Moreno RH, Hogg JC. Quantitative measurement of smooth muscle shortening in isolated pig trachea. J Appl Physiol 63: 1360-1365, 1987.
20. James AL. Relationship between airway wall thickness and airway hyperresponsiveness. In: Airway Wall Remodeling in Asthma, edited by Stewart AG. New York: CRC, 1997, p. 1-27.
21. Kraft M. The distal airways: are they important in asthma? Eur Respir J 14: 1403-1417, 1999.
22. Kuwano K, Bosken CH, Pare PD, Bai TR, Wiggs BR, Hogg JC. Small airways dimensions in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 148: 1220-1225, 1993.
23. Mauad T, Silva LF, Santos MA, Grinberg L, Bernardi FD, Martins MA, Saldiva PH, Dolhnikoff M. Abnormal alveolar attachments with decreased elastic fiber content in distal lung in fatal asthma. Am J Respir Crit Care Med 170: 857-862, 2004.
24. Mauad T, Xavier AC, Saldiva PH, Dolhnikoff M. Elastosis and fragmentation of fibers of the elastic system in fatal asthma. Am J Respir Crit Care Med 160: 968-975, 1999.
25. McKay KO, Hogg JC. The contribution of airway structure to early childhood asthma. Med J Aust 177, Suppl 6: S45-S47, 2002.
26. McParland BE, Pare PD, Johnson PR, Armour CL, Black JL. Airway basement membrane perimeter in human airways is not a constant; potential implications for airway remodeling in asthma. J Appl Physiol 97: 556-563, 2004.
27. Noble PB, Sharma A, McFawn PK, Mitchell HW. Elastic properties of the bronchial mucosa: epithelial unfolding and stretch in response to airway inflation. J Appl Physiol 99: 2061-2066, 2005.
28. Oliver MN, Fabry B, Marinkovic A, Mijailovich SM, Butler JP, Fredberg JJ. Airway hyperresponsiveness, remodeling, and smooth muscle mass: right answer, wrong reason? Am J Respir Cell Mol Biol 37: 264-272, 2007.
29. Saetta M, Di Stefano A, Rosina C, Thiene G, Fabbri LM. Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am Rev Respir Dis 143: 138-143, 1991.
30. Saetta M, Turato G, Baraldo S, Zanin A, Braccioni F, Mapp CE, Maestrelli P, Cavallesco G, Papi A, Fabbri LM. Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am J Respir Crit Care Med 161: 1016-1021, 2000.
31. Sobonya RE. Quantitative structural alterations in long-standing allergic asthma. Am Rev Respir Dis 130: 289-292, 1984.
32. Tiddens HA, Pare PD, Hogg JC, Hop WC, Lambert R, de Jongste JC. Cartilaginous airway dimensions and airflow obstruction in human lungs. Am J Respir Crit Care Med 152: 260-266, 1995.
33. Ward C, Johns DP, Bish R, Pais M, Reid DW, Ingram C, Feltis B, Walters EH. Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma. Am J Respir Crit Care Med 164: 1718-1721, 2001.
34. Weibel ER. Morphometry of the Human Lung. Berlin: Springer; 1963.
35. Wilson JW, Li X, Pain MC. The lack of distensibility of asthmatic airways. Am Rev Respir Dis 148: 806-809, 1993.