Expression of Kv1.2 in microglia and its putative roles in modulating production of proinflammatory cytokines and reactive oxygen species

Journal of Neurochemistry

Volumn 106, Issue 5, 2008, Pages 2093-2105

  Li, Fan ^a,b   Lu, Jia ^c   Wu, Chun Yun ^a   Kaur, Charanjit ^b   Sivakumar, Viswanathan ^b   Sun, Jun ^a   Li, Shuqing ^a   Ling, Eng Ang ^b  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c DSO NATIONAL LABORATORIES   (Singapore)

Author keywords

Amoeboid microglial cells; Developing brain; Potassium channels; Proinflammatory cytokines; Reactive oxygen species

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOKINE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; POTASSIUM; POTASSIUM CHANNEL KV1.2; REACTIVE OXYGEN METABOLITE; TITYUS TOXIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; EXPERIMENTAL RAT; FLOW CYTOMETRY; HYPOXIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; MICROGLIA; MOUSE; NONHUMAN; PERINATAL PERIOD; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; CELL LINE; CELL MOVEMENT; CELLS, CULTURED; CYTOKINES; ENCEPHALITIS; GLIOSIS; HYPOXIA, BRAIN; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; KV1.2 POTASSIUM CHANNEL; MICE; MICROGLIA; OXIDATIVE STRESS; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 49549110735     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05559.x     Document Type: Article

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