Role for primary cilia in the regulation of mouse ovarian function

Developmental Dynamics

Volumn 237, Issue 8, 2008, Pages 2053-2060

  Johnson, Ellen T ^a   Nicola, Teodora ^a,b   Roarty, Kevin ^a   Yoder, Bradley K ^a   Haycraft, Courtney J ^a,c   Serra, Rosa ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Estrogen; Ift88 polaris Tg737; Intraflagellar transport; Mammary gland; Prx1 Cre

Indexed keywords

CRE RECOMBINASE; ESTRADIOL; ESTROGEN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESTRUS CYCLE; EUKARYOTIC FLAGELLUM; GENE DELETION; GRANULOSA CELL; MAMMARY GLAND; MOUSE; NONHUMAN; ORGANOGENESIS; OVARY FUNCTION; OVULATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOLOGICAL TRANSPORT; CILIA; ESTRADIOL; ESTROGENS; ESTROUS CYCLE; FEMALE; GRANULOSA CELLS; HOMEODOMAIN PROTEINS; INTEGRASES; MAMMARY GLANDS, ANIMAL; MICE; MICE, MUTANT STRAINS; OVULATION; PHENOTYPE; TUMOR SUPPRESSOR PROTEINS;

MUS;

EID: 49449117174     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21612     Document Type: Article

References (36)

1. Alvarez J, Sohn P, Zeng X, Doetschman T, Robbins DJ, Serra R. 2002. TGFbeta2 mediates the effects of hedgehog on hypertrophic differentiation and PTHrP expression. Development 129:1913-1924.
2. Britt KL, Findlay JK. 2002. Estrogen actions in ovary revisited. J Endocrinol 175:269-276.
3. Couse JF, Korach KS. 1999. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 20:358-417.
4. Davenport JR, Yoder BK. 2005. An incredible decade for the primary cilium: a look at a once-forgotten organelle. Am J Physiol Renal Physiol 289:F1159-F1169.
5. Feng Y, Manka D, Wagner KU, Khan SA. 2007. Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proc Natl Acad Sci U S A 104:14718-14723.
6. Fisher CR, Graves KH, Parlow AF, Simpson ER. 1998. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the Cyp19 gene. Proc Natl Acad Sci U S A 95:6965-6970.
7. Goldman JM, Murr AS, Cooper RL. 2007. The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. Birth Defects Res B Dev Reprod Toxicol 80:84-97.
8. Hatsell SJ, Cowin P. 2006. Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development 133:3661-3670.
9. Hatsell S, Frost AR. 2007. Hedgehog signaling in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 12:163-173.
10. Haycraft CJ, Zhang Q, Song B, Jackson WS, Detloff PJ, Serra R, Yoder BK. 2007. Intraflagellar transport is essential for endochondral bone formation. Development 134:307-316.
11. Herman B, Albertini DF. 1983. Microtubule regulation of cell surface receptor topography during granulosa cell differentiation. Differentiation 25:56-63.
12. Hogan B, Beddington R, Constantini F, Lacy E. 1994. Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
13. Howlin J, McBryan J, Martin F. 2006. Pubertal mammary gland development: insights from mouse models. J Mammary Gland Biol Neoplasia 11:283-297.
14. Imagawa W, Yang J, Guzman R, Satybrata N. 1994. Control of mammary gland development. In: Knobil E, Neil JD, editors. The physiology of reproduction. 2nd ed. New York: Raven Press, Ltd. p 1033-1063.
15. Korach KS, Couse JF, Curtis SW, Washburn TF, Lindzey J, Kimbro KS, Eddy EM, Migliaccio S, Snedeker SM, Lubahn DB, Schomberg DW, Smith EP. 1996. Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes. Recent Prog Horm Res 51:159-186.
16. Lewis MT, Ross S, Strickland PA, Sugnet CW, Jimenez E, Hui C, Daniel CW. 2001. The Gli2 transcription factor is required for normal mouse mammary gland development. Dev Biol 238:133-144.
17. Logan M, Martin JF, Nagy A, Lobe C, Olson EN, Tabin CJ. 2002. Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 33:77-80.
18. Mallepell S, Krust A, Chambon P, Brisken C. 2006. Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proc Natl Acad Sci U S A 103:2196-2201.
19. Mueller SO, Clark JA, Myers PH, Korach KS. 2002. Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha. Endocrinology 143:2357-2365.
20. Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, Woychik RP. 2000. The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination. Development 127:2347-2355.
21. Nickerson SC. 1989. Cilia on bovine mammary epithelium: ultrastructural observations. Cell Tissue Res 255:675-677.
22. Parmar H, Cunha GR. 2004. Epithelialstromal interactions in the mouse and human mammary gland in vivo. Endocr Relat Cancer 11:437-458.
23. Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, Witman GB, Cole DG. 2000. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 151:709-18.
24. Rosenfeld CS, Murray AA, Simmer G, Hufford MG, Smith MF, Spears N, Lubahn DB. 2000. Gonadotropinb induction of ovulation and corpus luteum formation in young estrogen receptor-alpha knockout mice. Biol Reprod 62:599-605.
25. Russell MC, Cowan RG, Harman RM, Walker AL, Quirk SM. 2007. The hedgehog signaling pathway in the mouse ovary. Biol Reprod 77:226-236.
26. Satir P, Christensen ST. 2007. Overview of structure and function of mammalian cilia. Annu Rev Physiol 69:377-400.
27. Serra R. 2008. The role of intraflagellar transport and primary cilia in skeletal development. Anat Rec (in press).
28. Silberstein GB. 2001. Tumour-stromal interactions. Role of the stroma in mammary development. Breast Cancer Res 3:218-223.
29. Song B, Haycraft CJ, Seo HS, Yoder BK, Serra R. 2007. Development of the postnatal growth plate requires intraflagellar transport proteins. Dev Biol 305:202-216,
30. Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
31. Teilmann SC, Christensen ST. 2005. Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs. Cell Biol Int 29:340-346.
32. Teilmann SC, Byskov AG, Pedersen PA, Wheatley DN, Pazour GJ, Christensen ST. 2005. Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs. Mol Reprod Dev 71:444-452.
33. Teilmann SC, Clement CA, Thorup J, Byskov AG, Christensen ST. 2006. Expression and localization of the progesterone receptor in mouse and human reproductive organs. J Endocrinol 191: 525-535.
34. Toda K, Takeda K, Okada T, Akira S, Saibara T, Kaname T, Yamamura K, Onishi S, Shizuta Y. 2001. Targeted disruption of aromatase P450 gene (Cyp19) in mice and their ovarian and uterine response to 17β-oestradiol. J Endocrinol 170:99-111.
35. Yamazaki K, Eyden BP. 1995. Ultrastructural and immunohistochemical observations on intralobular fibroblasts of human breast, with observations on the CD34 antigen. J Submicrosc Cytol Pathol 27:309-323.
36. Yoder BK, Tousson A, Millican L, Wu JH, Bugg CE, Jr., Schafer JA, Balkovetz DF. 2002. Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium. Am J Physiol Renal Physiol 282:F541-F552.