Harnessing the power of bacteria to protect the gut

New England Journal of Medicine

Volumn 359, Issue 7, 2008, Pages 756-

  Abreu, Maria T ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; GASTROINTESTINAL AGENT; TOLL LIKE RECEPTOR 5 AGONIST;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CELL PROLIFERATION; DRUG MECHANISM; HUMAN; INTESTINE INJURY; IONIZING RADIATION; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE ABSORPTION; STEM CELL;

ANIMALS; APOPTOSIS; FLAGELLIN; INTESTINE, SMALL; LIPOPOLYSACCHARIDES; MACACA MULATTA; MICE; RADIATION INJURIES, EXPERIMENTAL; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; RECOMBINANT PROTEINS; TOLL-LIKE RECEPTOR 5; WHOLE-BODY IRRADIATION;

EID: 49449107666     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr0804223     Document Type: Article

References (6)

1. Burdelya LG, Krivokrysenko VI, Tallant TC, et al. An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 2008;320:226-30.
2. Abrams GD, Bauer H, Sprinz H. Influence of the normal flora on mucosal morphology and cellular renewal in the ileum: a comparison of germ-free and conventional mice. Lab Invest 1963;12:355-64.
3. Fukata M, Chen A, Klepper A, et al. Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine. Gastroenterology 2006;131:862-77.
4. Kaiser GC, Yan F, Polk DB. Conversion of TNF alpha from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase. Exp Cell Res 1999;249:349-58.
5. Riehl T, Cohn S, Tessner T, Schloemann S, Stenson WF. Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism. Gastroenterology 2000;118:1106-16.
6. Chen R, Alvero AB, Silasi DA, Steffensen KD, Mor G. Cancers take their Toll - the function and regulation of Toll-like receptors in cancer cells. Oncogene 2008;27:225-33.