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For representative examples of capsular assemblies made with coordinative covalent bonds, see: a
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For an example of a hydrophobically driven self-assembled capsule, see: c
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Although the studies reported here were performed using 1 M KCl, titration experiments of mAGcat with KCl show the presence of 31% hexadecamer even with 0.6 mM KCl Figure S17
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Although the studies reported here were performed using 1 M KCl, titration experiments of mAGcat with KCl show the presence of 31% hexadecamer even with 0.6 mM KCl (Figure S17).
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Studies with 5′-GMP have also shown that it self-assembles with low fidelity in aqueous KCl solutions but only at very high concentrations (0.15-1.0 M), giving a mixture of columnar aggregates of indefinite length (stacks of <24-87 tetrads): (a) Fisk, C. L.; Becker, E. D.; Miles, H. T.; Pinnavaia, T. J. J. Am. Chem. Soc. 1982, 104, 3307-3314.
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Studies with 5′-GMP have also shown that it self-assembles with low fidelity in aqueous KCl solutions but only at very high concentrations (0.15-1.0 M), giving a mixture of columnar aggregates of indefinite length (stacks of <24-87 tetrads): (a) Fisk, C. L.; Becker, E. D.; Miles, H. T.; Pinnavaia, T. J. J. Am. Chem. Soc. 1982, 104, 3307-3314.
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From the CD results, it can be inferred that the helical twist between the planar tetrads is very similar for the hexadecamers of mAGcat and mAGi due to the relative stereochemical arrangements of the subunits. For further information, see: Paramasivan, S.; Rujan, I.; Bolton, P. H. Methods 2007, 43, 324-331.
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From the CD results, it can be inferred that the helical twist between the planar tetrads is very similar for the hexadecamers of mAGcat and mAGi due to the relative stereochemical arrangements of the subunits. For further information, see: Paramasivan, S.; Rujan, I.; Bolton, P. H. Methods 2007, 43, 324-331.
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Minimizations were performed using: AMBER* MacroModel, Version 9.5, Maestro 8.0.315; Schrödinger, LLC: New York, 2007, representing water as a continuum solvent
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Minimizations were performed using: AMBER* (MacroModel), Version 9.5, Maestro 8.0.315; Schrödinger, LLC: New York, 2007, representing water as a continuum solvent.
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These thermodynamic parameters are similar to those determined from the calorimetric measurements obtained for DNA aptamers capable of forming G-quadruplexes. See: (a) Olsen, C. M, Gmeiner, W. H, Marky, L. A. J. Phys. Chem. B 2006, 110, 6962-6969
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These thermodynamic parameters are similar to those determined from the calorimetric measurements obtained for DNA aptamers capable of forming G-quadruplexes. See: (a) Olsen, C. M.; Gmeiner, W. H.; Marky, L. A. J. Phys. Chem. B 2006, 110, 6962-6969.
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