Debromoaplysiatoxin in Lyngbya-dominated mats on manatees (Trichechus manatus latirostris) in the Florida King's Bay ecosystem

Toxicon

Volumn 52, Issue 2, 2008, Pages 385-388

  Harr, Kendal E ^a   Szabo, Nancy J ^b   Cichra, Mary ^b   Phlips, Edward J ^b  

^a FVP Consultants Inc   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Debromoaplysiatoxin; Dermatitis; Florida; Lyngbya; Manatee

Indexed keywords

DEBROMOAPLYSIATOXIN; LYNGBYATOXIN A;

AQUATIC ENVIRONMENT; ARTICLE; CYANOBACTERIUM; LAKE; LYNGBYA; NONHUMAN; PRIORITY JOURNAL; PYODERMA GANGRENOSUM; RIVER; TRICHECHUS MANATUS; UNITED STATES;

ANIMALS; CARCINOGENS; CYANOBACTERIA; DERMATITIS; ECOSYSTEM; LYNGBYA TOXINS; SEAWEED; SKIN ULCER; TRICHECHUS MANATUS; WATER POLLUTANTS, CHEMICAL;

LYNGBYA; TRICHECHIDAE; TRICHECHUS MANATUS LATIROSTRIS;

EID: 49449089105     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.05.016     Document Type: Article

References (27)

1. Berry J.P., Gantar M., Gawley R.E., Wang M., and Rein K.S. Pharmacology and toxicology of phayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida Everglades. Comp. Biochem. Physiol C. Toxicol. Pharmacol. 139 (2004) 231-238
2. Bledsoe E.L., Harr K.E., Cichra M.F., Phlips E.J., Bonde R.K., and Lowe M. A comparison of algal mat communities associated with free-ranging and captive Florida manatees (Trichechus manatus latirostris). Mar. Mamm. Sci. 22 4 (2006) 997-1003
3. Bossart G.D., Ewing R.Y., Lowe M., Sweat M., Decker S.J., Walsh C.J., Ghim S.J., and Jenson A.B. Viral papillomatosis in Florida manatees (Trichechus manatus latirostris). Exp. Mol. Pathol. 72 (2002) 37-48
4. Capper A., Tibbetts I.R., O'Neil J.M., and Shaw G.R. The fate of Lyngbya majuscula toxins in three potential consumers. J. Chem. Ecol. 31 (2005) 1595-1606
5. Cardellina J.H., Marner F.J., and Moore R.E. Seaweed dermatitis: structure of lyngbyatoxin A. Science 204 (1979) 193-195
6. Carmichael W.W., Evans W.R., Yin Q.Q., Bell P., and Moczydlowski E. Evidence for paralytic shellfish poisons in the freshwater cyanobacterium Lyngbya wollei (Farlow ex Gomont) comb. nov. Appl. Environ. Microbiol. 63 (1997) 3104-3110
7. Dubose C., Langeland K., and Phlips E.J. Problem freshwater algae and their control in Florida. Aquatics 19 (1997) 4-13
8. Fujiki H., Sugimura T., and Moore R.E. New classes of environmental tumor promoters: indole alkaloids and polyacetates. Environ. Health Perspect. 50 (1983) 85-90
9. Fujiki H., Tanaka Y., Miyake R., Kikkawa U., Nishizuka Y., and Sugimura T. Activation of calcium-activated, phospholipid-dependent protein kinase (protein kinase C) by new classes of tumor promoters: teleocidin and debromoaplysiatoxin. Biochem. Biophys. Res. Commun. 120 2 (1984) 339-343
10. Fujiki J., Ikegami K., Hakii H., Suganuma M., Yamaizumi Z., Yamazato K., Moore R.E., and Sugimua T. A blue-green alga from Okinawa contains aplysiatoxins, the third class of tumor promoters. Jpn. J. Cancer Res. 76 (1985) 257-259
11. Hallegraeff G.M. A review of harmful algal blooms and their apparent global rise. Phycologia 32 (1993) 79-99
12. Ito E., and Nagai H. Morphological observations of diarrhea in mice caused by aplysiatoxin, the causative agent of the red alga Gracilaria coronopifolia poisoning in Hawaii. Toxicon 36 (1998) 1913-1920
13. Komárek J., Kling H., and Komárková J. Filamentous cyanobacteria. In: Wehr J.D., and Sheath R.G. (Eds). Freshwater Algae of North America (2003), Academic Press, New York 117-196
14. Langtimm C.A., and Beck C.A. Lower survival probabilities for adult Florida manatees in years with intense coastal storms. Ecol. Appl. 13 1 (2003) 257-268
15. Mataraza L.K., Terrell J.B., Munson A.B., and Canfield E. Changes in submersed macrophytes in relation to tidal storm surges. J. Aquat. Plant Manag. 37 (1999) 3-12
16. Mynderse J.S., and Moore R.E. Antileukemia activity in the Oscillatoriaceae: isolation of debromoaplysiatoxin from Lyngbya. Science 196 (1977) 538-540
17. Nagai H., Yasumoto T., and Hokama Y. Aplysiatoxin and debromoaplysiatoxin as the causative agents of red alga Gracilaria coronopifolia poisoning in Hawaii. Toxicon 37 (1996) 753-761
18. Onodera H., Satake M., Oshima Y., Yasumoto T., and Carmichael W.W. New saxitoxin analogues from the freshwater filamentous cyanobacterium Lyngbya wollei. Nat. Toxins 5 (1997) 146-151
19. Osborne N.J., Webb P.M., and Shaw G.R. The toxins of Lyngbya majuscula and their human and ecological health effects. Environ. Int. 27 (2001) 381-392
20. Phlips E.J. The state of toxic freshwater algae in Florida. Aquatics 24 (2002) 8-19
21. Phlips E.J., Hansen P., and Velardi T. Effects of the herbicide diquat on the growth of phytoplankton. Bull. Environ. Contam. Toxicol. 49 (1992) 750-756
22. Quinlan E.L., Phlips E.J., Donnelly K.A., Jett C.H., Sleszynski P., and Keller S. Primary producer biomass and nutrient loading in Silver Springs, Florida, USA. Aquat. Bot. 88 (2008) 247-255
23. Rodgers, J.H., Johnson, B.M., 2007. Crystal River Lyngbya Risk and Management Assessment. Annual Progress Report to the Florida Department of Environmental Protection.
24. Shimizu Y. Microalgal metabolites. Curr. Opin. Microbiol. 6 (2003) 236-243
25. Solomon A.E., and Stoughton R.B. Dermatitis from purified sea algae toxin (debromoaplysiatoxin). Arch. Dermatol. 114 9 (1978) 1333-1335
26. Teneva I., Asparuhova D., Dzhambazov B., Mladenov R., and Schirmer K. The freshwater cyanobacterium Lyngbya aerugineo-coerulea produces compounds toxic to mice and to mammalian and fish cells. Environ. Toxicol. 18 (2003) 9-20
27. Yasumoto T. Fish poisoning due to toxins of microalgal origins in the Pacific. Toxicon 36 (1998) 1515-1518