Chronic wound state exacerbated by oxidative stress in Pax6+/- aniridia-related keratopathy

Journal of Pathology

Volumn 215, Issue 4, 2008, Pages 421-430

  Ou, J ^a   Walczysko, P ^a   Kucerova, R ^a   Rajnicek, A M ^a   McCaig, C D ^a   Zhao, M ^b   Collinson, J M ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aniridia; Aniridic keratopathy; Cornea; Haploinsufficiency; Oxidative stress; Pax6; Pharmacology

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA ACTIN; BIOLOGICAL MARKER; CALCIUM; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; TRANSCRIPTION FACTOR PAX6; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIRIDIA; ARTICLE; CELL NUCLEUS; CHRONIC WOUND; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA OPACITY; DISEASE EXACERBATION; FIBROBLAST; HETEROZYGOSITY; KERATOPATHY; METAPLASIA; MOUSE; MYOFIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; OXIDATIVE STRESS; PAX6 GENE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEOMICS; SIGNAL TRANSDUCTION; WOUND HEALING;

ANIMALS; ANIRIDIA; CHRONIC DISEASE; CORNEAL DISEASES; EPITHELIUM, CORNEAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; EYE PROTEINS; GLUTATHIONE; HOMEODOMAIN PROTEINS; HYDROGEN PEROXIDE; MICE; MICE, INBRED CBA; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, SCANNING; MODELS, ANIMAL; OXIDATIVE STRESS; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 49449084501     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2371     Document Type: Article

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