Immunization with cDNA of a novel P-III type metalloproteinase from the rattlesnake Crotalus durissus durissus elicits antibodies which neutralize 69% of the hemorrhage induced by the whole venom

Toxicon

Volumn 52, Issue 2, 2008, Pages 302-308

  Azofeifa Cordero, Gabriela ^a   Arce Estrada, Viviana ^a   Flores Díaz, Marietta ^a   Alape Girón, Alberto ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

DNA immunization; Gene Gun; Therapeutic antivenom

Indexed keywords

COMPLEMENTARY DNA; GOLD; METALLOPROTEINASE; PLASMID DNA; SNAKE VENOM; TUNGSTEN; VENOM ANTISERUM; ZINC;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; BLEEDING; CONTROLLED STUDY; CROTALUS DURISSUS DURISSUS; DNA IMMUNIZATION; DNA SEQUENCE; ENVENOMATION; GENE GUN; MICROPARTICLE ENZYME IMMUNOASSAY; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; SNAKE;

AMINO ACID SEQUENCE; ANIMALS; ANTIVENINS; BASE SEQUENCE; CROTALID VENOMS; DNA, COMPLEMENTARY; HEMORRHAGE; METALLOPROTEASES; MICE; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; SEQUENCE ANALYSIS, DNA; SKIN;

CROTALUS DURISSUS DURISSUS; MURINAE; MUS; VIPERIDAE;

EID: 49449083279     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.05.023     Document Type: Article

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