The effect of post-translational modifications on the hemorrhagic activity of snake venom metalloproteinases

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 138, Issue 1, 2004, Pages 23-32

  Garcia L T ^a   Parreiras E Silva, L T ^a   Ramos, O H P ^a   Carmona, A K ^b   Bersanetti, P A ^b   Selistre De Araujo, H S ^a  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

ACLH; Bothrops; Glycosylation; Hemorrhage; Jararhagin; Metalloproteinase; metalloproteinase; MP; Post translational modification; rCDJARA; recombinant snake venom metalloproteinase; rsvMP; Snake venom; snake venom metalloproteinase; svMP

Indexed keywords

BATROXOBIN; ENZYME PRECURSOR; FIBRINOGEN; FIBRONECTIN; METALLOPROTEINASE; SNAKE VENOM; ZINC;

ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BLEEDING; CATALYSIS; CONTROLLED STUDY; DEGLYCOSYLATION; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN PURIFICATION; SKIN; SNAKE;

AGKISTRODON; AGKISTRODON CONTORTRIX; AGKISTRODON CONTORTRIX LATICINCTUS; BOTHROPS; BOTHROPS JARARACA; SERPENTES;

EID: 4143110311     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2004.04.004     Document Type: Article

References (42)

1. Anderson S.G., Ownby C.L. Characterization of proteinase H from Crotalus adamanteus venom: lack of citotoxity on rat aorta endothelial cells, thrombin-like activity and role glycosylation. Toxicon. 33:1995;261
2. Bjarnason J.B., Fox J.W. Hemorrhagic metalloproteinases from snake venom. Pharmacol.Ther. 62:1994;325-372
3. Bjarnason J.B., Fox J.W. Snake venom metalloendopeptidases: reprolysins. Methods Enzymol. 248:1995;345-368
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254
5. Bode W., Gomis-Rüth F.-X., Stöcker W. Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the "metzincins" FEBS Lett. 331:1993;134-140
6. Chagas J.R., Juliano L., Prado E.S. Intramolecularly quenched fluorogenic tetrapeptide substrates for tissue and plasma kallikreins. Anal. Biochem.volume-nr>192. 1990;419-425
7. Chang C., Werb Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol. 11:2001;S37-S43
8. Chung C.M.C., Ponnudurai G., Kataoka M., Shimizu S., Tan H.N. Structural studies on a major hemorrhagin (rhodostoxin) from the venom of Calloselasma rhodostoma (Malayan pit viper). Arch. Biochem. Biophys. 325:1996;199-208
9. Elbein A.D. Glycosidase inhibitors: inhibitors of N-linked oligosaccharide processing. FASEB J. 5:1991;3055-3063
10. Guan A.L., Retzios A.D., Henderson G.N., Markland F.S. Jr. Purification and characterization of a fibrinolytic enzyme from venom of the southern copperhead snake Agkistrodon contortrix contortrix. Arch. Biochem. Biophys. 289:1991;197-207
11. Hart G.W. Glycosylation. Curr. Opin. Cell Biol. 4:1992;1017-1023
12. Hite L.A., Jia L.G., Bjarnason J.B., Fox J.W. cDNA sequences for four snake venom metalloproteinases: structure, classification, and their relationship to mammalian reproductive proteins. Arch. Biochem. Biophys. 308:1994;182-191
13. Hooper N.M. Families of zinc metalloproteases. FEBS Lett. 354:1994;1-6
14. Jeon O.H., Kim D.S. Molecular cloning and functional characterization of a snake venom metaloprotease. Eur. J. Biochem. 263:1999;256-263
15. Johnson E.K., Ownby C.L. Isolation of a hemorrhagic toxin from the venom of Agkistrodon contortrix laticinctus (Broad-banded copperhead) and pathogenesis of the hemorrhage induced by the toxin in mice. Int. J. Biochem. 25:1993;267-278
16. Kamiguti A.S., Theakston R.G.D., Desmond H.P., Hutton R.A. Systemic haemorrhage in rats induced by a haemorrhagic fraction from Bothrops jararaca venom. Toxicon. 29:1991;1097-1105
17. 1 integrin (gpIa/Iia) by jararhagin, a haemorrhagic metalloproteinase from Bothrops jararaca venom. Br. J. Haematol. 89:1995;8
18. Kamiguti A.S., Hay C.R.M., Zuzel M. Cleavage of von Willebrand factor by jararhagin, a haemorrhagic metalloproteinase from Bothrops jararaca venom. Toxicon. 33:1995;260
19. Kishimoto M., Takahashi T. Molecular cloning of HR1A and HR1B, high molecular hemorrhagic factors from Trimeresurus flavoviridis venom. Toxicon. 40:2002;1369-1375
20. Kornfeld R., Kornfeld S. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 54:1985;631-664
21. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685
22. Li Q., Colberg T.R., Ownby C.L. Purification and characterization of two high molecular weight hemorrhagic toxins from Crotalus viridis viridis using monoclonal antibodies. Toxicon. 31:1993;711-722
23. Markland F.S. Snake venoms and the hemostatic system. Toxicon. 36:1998;1749-1800
24. Miyata T., Takeya H., Ozeki Y., Arakawa M., Tokunaga F., Iwanaga S., Satoh T.O. Primary structure of haemorrhagic protein, HR2a, isolated from the venom of Trimeresurus flavoviridis. J. Biochem. 105:1989;847-853
25. Paine M.J.I., Desmond H.P., Theakston R.D.G., Crampton J.M. Purification, cloning, and molecular characterization of a high molecular weight haemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. J. Biol. Chem. 267:1992;22869-22876
26. Perkins S.J., Willians A.F., Rademacher T.W., Dwek R.A. The thy-l glycoprotein: a three-dimensional model. Trends Biochem. Sci. 13:1988;302-303
27. Ramos O.H.P., Carmona A.K., Selistre-de-Araujo H.S. Expression, refolding, and in vitro activation of a recombinant snake venom pro-metalloprotease. Protein Expr. Purif. 28:2003;34-41
28. Rucavado A., Lomonte B., Ovadia M., Gutiérrez J.M. Local tissue damage induced by BaP1, a metalloproteinase isolated from Bothrops asper (Terciopelo) snake venom. Exp. Mol. Pathol. 63:1995;186-199
29. Sanchez E.F., Diniz C.R., Richardson M. The complete amino acid sequence of the haemorrhagic factor LHFII, a metalloproteinase isolated from the venom of the bushmaster snake (Lachesis muta muta). FEBS Lett. 282:1991;178-182
30. Selistre-de-Araujo H.S., Ownby C.L. Molecular cloning and sequence analysis of cDNAs for metalloproteinases from broad-banded copperhead. Agkistrodon contortrix laticinctus. Arch. Biochem. Biophys. 320:1995;141-148
31. Selistre-de-Araújo H.S., Souza E.L., Beltramini L.M., Ownby C.L., Souza D.H.F. Expression, refolding and activity of a recombinant non-hemorrhagic snake venom metalloprotease. Protein Expr. Purif. 19:2000;41-47
32. Takeuchi M., Kobata A. Structures and functional roles of the sugar chains of human erythropoietins. Glycobiology. 1:1991;337-346
33. Takeya H., Arakawa M., Miyata T., Iwanaga S., Omori-Satoh T. Primary structure of H2-proteinase, a non-haemorrhagic metalloproteinase, isolated from venom of the Habu snake, Trimeresurus flavoviridis. J. Biochem. 106:1989;151-157
34. Takeya H., Oda K., Miyata T., Omori-Satoh T., Iwanaga S. The complete amino acid sequence of the high molecular mass haemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis. J. Biol. Chem. 265:1990;16068-16073
35. Tan N.H., Ponnudurai G., Chung C.M. Proteolytic specifity of rhodostoxin, the major hemorrhagin of Calloselasma rhodostoma (Malayan pit viper) venom. Toxicon. 35:1997;979-984
36. Terada S., Hori J., Fujimura S., Kimoto E. Purification and amino acid sequence of brevilysin L6, a non-hemorrhagic metalloproteinase from Agkistrodon halys brevicaudus venom. J. Biochem. 125:1999;64-69
37. Trummal K., Vija H., Subbi J., Sligur J. MALDI-TOF mass spectrometry analysis of substrate specificity of lebetase, a direct-acting fibrinolytic metalloproteinase from Vipera lebetina snake venom. Bichimica et Biophysica Acta (BBA)-Prot. Struct. Mol. Enz. 1476:2000;331-336
38. Veiga S.S., Chammas R., Cella N., Brentani R.R. Glycosylation of β-1 integrins in B 16-F10 mouse melanoma cells as determinant of differential binding and acquisition of biological activity. Int. J. Cancer. 61:1995;420-424
39. Veiga S.S., Gremski W., Santos V.L., Feitosa L., Mangili O.C., Nader H.B., Dietrich C.P., Brentani R.R. Oligosaccharide residues of Loxosceles intermédia (brown spider) venom proteins: dependence on glycosylation for dermonecrotic activity. Toxicon. 37:1999;587-607
40. Willis T.W., Tu A.T. Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from Western diamondback rattlesnake venom. Biochemistry. 27:1988;4769-4777
41. Wormald M.R., Dwek R.A. Glycoproteins: glycan presentation and protein-fold stability. Structure. 7:1999;R155-R160
42. You W.K., Seo H.J., Chung K.H., Kim D.S. A novel metalloprotease from Gloydius halys venom induces endothelial cell apoptosis through its protease and disintegrin-like domains. J. Biochem. 134:2003;739-749