Bystander help within a polyepitope DNA vaccine improves immune responses to influenza antigens

Scandinavian Journal of Immunology

Volumn 60, Issue 4, 2004, Pages 363-371

  Baird, M ^a   Wilson, R ^a   Young, L ^a   Williman, J ^a   Young, S ^a   Wilson, M ^a   Slobbe, L ^a   Lockhart, E ^a   Buchan, G ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; CYTOKINE; DNA VACCINE; EPITOPE; INFLUENZA VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; PLASMID DNA; POLYEPITOPE VACCINE; RECOMBINANT ANTIGEN; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VIRUS HEMAGGLUTININ;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA; INFLUENZA VACCINATION; INFLUENZA VIRUS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; VACCINATION; VIRUS INFECTION;

ANIMALS; BASE SEQUENCE; BIOLISTICS; CHICKENS; CYTOCHROMES C; CYTOTOXICITY, IMMUNOLOGIC; DNA, RECOMBINANT; EPITOPES; FEMALE; H-2 ANTIGENS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; INFLUENZA VACCINES; INTERLEUKIN-5; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MOTHS; OVALBUMIN; PLASMIDS; RECOMBINANT PROTEINS; T-LYMPHOCYTE SUBSETS; VACCINES, DNA;

EID: 4944255571     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0300-9475.2004.01487.x     Document Type: Article

References (30)

1. Ada G, Ramshaw I. DNA vaccination. Expert Opin Emerg Drugs 2003;8:27-35.
2. Smith SG. The polyepitope approach to DNA vaccination. Curr Opin Mol Ther 1999;1:10-5.
3. Duraiswamy J, Sherritt M, Thomson S et al. Therapeutic LMP1 polyepitope vaccine for EBV-associated Hodgkin disease and nasopharyngeal carcinoma. Blood 2003;101:3150-6.
4. McConkey SJ, Recce WH, Moorthy VS et al. Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nat Med 2003;9:729-35.
5. Perkins DL, Berriz G, Kamradt T, Smith JA, Gefter ML. Immunodominance: intramolecular competition between T cell epitopes. J Immunol 1991;146:2137-44.
6. Wang Y, Smith JA, Kamradt T, Gefter ML, Perkins DL. Silencing of immunodominant epitopes by contiguous sequences in complex synthetic peptides. Cell Immunol 1992;143:284-97.
7. Velders MP, Weijzen S, Eiben GL et al. Defined flanking spacers and enhanced proteolysis is essential for eradication of established tumors by an epitope string DNA vaccine. J Immunol 2001;166:5366-73.
8. An LL, Whitton JL. A multivalent minigene vaccine, containing B-cell, cytotoxic T-lymphocyte, and Th epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen. J Virol 1997;71:2292-302.
9. Thomson SA, Sherritt MA, Medveczky J et al. Delivery of multiple CDS cytotoxic T cell epitopes by DNA vaccination. J Immunol 1998;160:1717-23.
10. Rooney JF, Wohlenberg C, Cremer KJ, Moss B, Notkins AL, Carbone FR. Immunization with a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: long-term protection and effect of revaccination. J Virol 1988;62:1530-4.
11. Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. T cell receptor antagonist peptides induce positive selection. Cell 1994;76:17-27.
12. McReynolds L, O'Malley BW, Nisbet AD et al. Sequence of chicken ovalbumin mRNA. Nature 1978;273:723-8.
13. Air GM. Sequence relationships among the hemagglutinin genes of 12 subtypes of influenza A virus. Proc Natl Acad Sci USA 1981;78:7639-43.
14. Winter G, Fields S, Brownlee GG. Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype. Nature 1981;292:72-5.
15. Chan SK, Margoliash E. Properties and primary structure of the cytochrome c from the flight muscles of the moth, Samia cynthia. J Biol Chem 1966;241:335-48.
16. Swanson MS, Zieminn SM, Miller DD, Garber EA, Margoliash E. Developmental expression of nuclear genes that encode mitochondrial proteins: insect cytochromes c. Proc Natl Acad Sci USA 1985;82:1964-8.
17. Reff ME, Carner K, Chambers KS et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 1994;83:435-45.
18. Wales J, Baird M, Davies N, Buchan G. Fusion of interleukin-2 to subunit antigens increase their antigenicity in vitro due to an interleukin-2 receptor beta-mediated antigen uptake mechanism. Scand J Immunol 2003;58:367-73.
19. Faulkner L, Buchan G, Slobbe L et al. Influenza hemagglutinin peptides fused to interferon gamma and encapsulated in liposomes protects mice against influenza infection. Vaccine 2003;21:932-9.
20. Andersen PS, Geisler C, Buus S, Mariuzza RA, Karjalainen K. Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens. J Biol Chem 2001;276:33452-7.
21. Ritchie DS, Hermans IF, Lumsden JM et al. Dendritic cell elimination as an assay of cytotoxic T lymphocyte activity in vivo. J Immunol Methods 2000;246:109-17.
22. Yellen-Shaw AJ, Eisenlohr LC. Regulation of class I-restricted epitope processing by local or distal flanking sequence. J Immunol 1997;158:1727-33.
23. Shastri N, Serwold T, Gonzalez F. Presentation of endogenous peptide/MHC class I complexes is profoundly influenced by specific C-terminal flanking residues. J Immunol 1995;155:4339-46.
24. + cytotoxic T cells: implications for vaccine design. Proc Nad Acad Sci USA 1995;92:5845-9.
25. Suhrbier A. Multi-epitope DNA vaccines. Immunol Cell Biol 1997;75:402-8. [Review].
26. Coles RM, Mueller SN, Heath WR, Carbone FR, Brooks AG. Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1. J Immunol 2002;168:834-8.
27. Renz H, Bradley K, Larsen GL, McCall C, Gelfand EW. Comparison of the allergenicity of ovalbumin and ovalbumin peptide 323-339. Differential expansion of V beta-expressing T cell populations. J Immunol 1993;151:7206-13.
28. An LL, Rodriguez F, Harkins S, Zhang J, Whitton JL. Quantitative and qualitative analyses of the immune responses induced by a multivalent minigene DNA vaccine. Vaccine 2000;18:2132-41.
29. Weiss R, Scheiblhofer S, Freund J, Ferreira F, Livey I, Thalhamer J. Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines. Vaccine 2002;20:3148-54.
30. Bembridge GP, Rodriguez N, Garcia-Beato R, Nicolson C, Melero JA, Taylor G. Respiratory syncytial virus infection of gene gun vaccinated mice induces Th2-driven pulmonary eosinophilia even in the absence of sensitisation to the fusion (F) or attachment (G) protein. Vaccine 2000;19:1038-46.