Northern ring conformation of methanocarba-adenosine 5′-triphosphate required for activation of P2X receptors

Drug Development Research

Volumn 61, Issue 4, 2004, Pages 227-232

  Dunn, Philip M ^a   Kim, Hak Sung ^b   Jacobson, Kenneth A ^c   Burnstock, Geoffrey ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b Wonkwang University   (South Korea)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

ATP; P2X receptors; Structure activity relationship

Indexed keywords

4 (6 AMINO 9H PURIN 9 YL) 1 (TRIPHOSPHORYLOXYMETHYL)BICYCLO[3.1.0]HEXANE 2,3 DIOL; 5 (6 AMINO 9H PURIN 9 YL) 1 (TRIPHOSPHORYLOXYMETHYL)BICYCLO[3.1.0]HEXANE 2,3 DIOL; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; MRS 2312; MRS 2340; PURINE P2X RECEPTOR; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2Y RECEPTOR; RECOMBINANT RECEPTOR; RIBOSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; DRUG BINDING SITE; DRUG CONFORMATION; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; MAMMAL CELL; MEMBRANE CURRENT; NEWBORN; NONHUMAN; PATCH CLAMP; RAT; RECEPTOR UPREGULATION; SPINAL GANGLION;

EID: 4944254839     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10381     Document Type: Article

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