Potent antioxidative and antigenotoxic activity in aqueous extract of Japanese rice bran - Association with peroxidase activity

Phytotherapy Research

Volumn 18, Issue 8, 2004, Pages 628-633

  Higashi Okai, Kiyoka ^a   Kanbara, Keiko ^a   Amano, Kanako ^a   Hagiwara, Akiko ^a   Sugita, Chie ^a   Matsumoto, Norie ^a   Okai, Yasuji ^b  

^a Hiroshima Jogakuin University   (Japan)

^b Osaka Kun ei Women's College   (Japan)

Author keywords

Antigenotoxitic activity; Antioxidant; Peroxidase; Rice bran

Indexed keywords

3 AMINO 1,4 DIMETHYL 5H PYRIDO[4,3 B]INDOLE; ACETONE; ALPHA TOCOTRIENOL; ALUMINUM CHLORIDE; ANTIOXIDANT; GAMMA ORYZANOL; HORSERADISH PEROXIDASE; HYDROPEROXIDE; LINOLEIC ACID; METHANOL; ORYZA SATIVA JAPONICA EXTRACT; OXYGEN RADICAL; PEROXIDASE; PLANT EXTRACT; TOCOPHEROL; UNCLASSIFIED DRUG;

ARTICLE; CANCER; CARDIOVASCULAR DISEASE; CHEMICAL ANALYSIS; CHRONIC DISEASE; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; EXTRACTION; GENE EXPRESSION; LIPID PEROXIDATION; MOLECULAR WEIGHT; NONHUMAN; ORYZA SATIVA JAPONICA; RICE BRAN; SALMONELLA TYPHIMURIUM; SUPERNATANT;

ANTIMUTAGENIC AGENTS; ANTIOXIDANTS; BACTERIAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, BACTERIAL; HORSERADISH PEROXIDASE; HUMANS; ORYZA SATIVA; PHYTOTHERAPY; PLANT EXTRACTS; SALMONELLA TYPHIMURIUM; SOS RESPONSE (GENETICS);

ARMORACIA RUSTICANA; JAPONICA; ORYZA SATIVA; ORYZA SATIVA (JAPONICA CULTIVAR-GROUP); SALMONELLA TYPHIMURIUM;

EID: 4944225006     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1576     Document Type: Article

References (18)

1. Ames BN, Shigenaga MK, Hagen TM. 1993. Oxidants, antioxidants, and the generative diseases of aging. Proc Natl Acad Sci USA 90: 7915-7922.
2. Asakawa T, Matsushita S. 1980. A colorimetric microdetermination of peroxide values utilizing alminum chloride as the catalyst. Lipids 15: 965-967.
3. Bradford MM. 1976. A rapid and sensitive method for the quantitation of micro-gram quantities of protein utilizing protein-dye binding. Anal Biochem 72: 248-254.
4. Halliwell B. 1997. Antioxidants and human diseases: a general introduction Nutr Review 55: 44-52.
5. Inoue Y, Ichiryu T, Yoshikawa K, et al. 1990. Induction of glutathione peroxidase by linoleic acid hydroperoxide in Hansenula mrakii. Agric Biol Chem 54: 3289-3293.
6. Kaneko T, Baba N, Matsuo M. 1994. Phospholipid hydroperoxides are significantly less toxic to cultured endothelial cells than fatty acid hydroperoxides Life Sci 55: 1443-1449.
7. Lyttle CR, DeSombre, ER. 1977. Uterine peroxidase as a marker for estrogen action. Proc Natl Acad Sci USA 74: 3162-3166.
8. Nunoshiba T, Ohtsuka A, Minamisako T, Nishioka H. 1984. Correlation between inactivating capacity of human saliva on mutagenecity of carcinogens and its peroxidase activity. Sci Engin Rev Doshisha Univ 25: 137-144.
9. Nicolosi RJ, Rogers EA, Hudson, JK. Orthoefer FT. 1994. Rice bran oil and its health benefits. In Rice Science and Technology, Marshall WE, Wadsworth JI (eds). Dekker: New York.
10. Okai Y, Higashi-Okai K, Nakamura S. 1993. Identification of heterogenous antimutagenic activities in the extract of edible brown seaweeds, Laminaria japonica (Makonbu) and Undaria pinnantifida (Wakame) by the umu gene expression system in Salmonella typhimurium (TA 1535/pSK 1002). Mutation Res 303: 63-70.
11. Qureshi AA, Mo H, Packer L. Peterson DM. 2000. Isolation and Identification of novel tocotrienols from rice bran with hypocholesterolemic, antioxidant, and antitumor properties. J Agric Food Chem 48: 3130-3140.
12. Saunders RM. 1990. The properties of rice bran as a food stuff. Cer Foods Worlds 35: 632-636.
13. Sheetharamaiah GS, Chabdrasekhara N. 1988. Hypocholesterolemic activity of oryzanol in rats. Nutr Rep Int 38: 927-935.
14. Shibuya N. 1984. Phenolic acids and their carbohydrate esters in rice endosperm cell walls. Phytochem 23: 2233-2237.
15. Steinmetz KA, Potter JD. 1996. Vegetables, fruit and cancer prevention J Amer Diet Assoc 96: 1072-1039.
16. Yamada M, Tsuda M, Nagao M, et al. 1979. Degradation of mutagens from pyrolysates of tryptophan, glutamic acid and globulin by myeloperoxidase. Biochem Biophys Res Commun 90: 769-776.
17. Yagi K. 1994. Lipid peroxides in hepatic, gastrointestinal and pancreatic diseases in Free Radicals in Diagnostic Medicine, Armstrong D. (ed.). Prenum Press: New York; 165-169.
18. Zielinski H, Kozlowska H. 2000. Antioxidant activity and total phenolics in selected cereal grains and their different morphological fractions. J Agric Food Chem 48: 2008-2016.