Effect of nortriptyline on intracellular Ca2+ handling and proliferation in human osteosarcoma cells

Basic and Clinical Pharmacology and Toxicology

Volumn 95, Issue 3, 2004, Pages 124-130

  Hsu, Shu Shong ^a   Huang, Chun Jen ^b,c   Chen, Jin Shyr ^a   Cheng, He Hsiung ^a   Chang, Hong Tai ^a   Jiann, Bang Ping ^a   Lin, Ko Long ^a   Wang, Jue Long ^a   Ho, Chin Man ^a   Jan, Chung Ren ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b TIAN SHENG MEMORIAL HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ANTIDEPRESSANT AGENT; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; ENDOPLASMIC RETICULUM ADENOSINE TRIPHOSPHATASE (CALCIUM); FURA 2; NORTRIPTYLINE; PHOSPHOLIPASE C; TETRAZOLIUM; THAPSIGARGIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL PROLIFERATION; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG EFFECT; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PRIORITY JOURNAL;

ANTIDEPRESSIVE AGENTS, TRICYCLIC; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; FLUORESCENT DYES; FURA-2; HUMANS; NORTRIPTYLINE; OSTEOSARCOMA; PROTEIN KINASE C; THAPSIGARGIN;

EID: 4944222707     PISSN: 17427835     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2004.950304.x     Document Type: Article

References (32)

1. Barry, E. L.: Expression of mRNAs for the alpha 1 subunit of voltage-gated calcium channels in human osteoblast-like cell lines and in normal human osteoblasts. Calcif. Tissue Int. 2000, 66, 145-150.
2. Berridge, M. J.: Elementary and global aspects of calcium signaling. J. Physiol. 1997, 499, 291-306.
3. 2+ signals. J. Cell. Sci. 2001, 114, 2213-2222.
4. Brini, M. & E. Carafoli: Calcium signalling: a historical account, recent developments and future perspectives. Cell. Mol. Life Sci. 2000, 57, 354-370.
5. Couture, L., R. Elie & P. A. Lavoie: Effect of antidepressants on ATP-dependent calcium uptake by neuronal endoplasmic reticulum. Can. J. Physiol. Pharmacol. 2001, 79, 946-952.
6. Franssen, E. J., P. W. Kunst, P. M. Bet, R. J. Strack van Schijndel, A. C. van Loenen & A. J. Wilhelm: Toxicokinetics of nortriptyline and amitriptyline: two case reports. Ther. Drug Monit. 2003, 25, 248-251.
7. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 1985, 260, 3440-3450.
8. Gu, Y., M. R. Preston, A. J. el Haj, J. Hamid, G. W. Zamponi, J. Howl, S. J. Publicover: Osteoblasts derived from load-bearing bones of the rat express both L- and T-like voltage-operated calcium channels and mRNA for alpha 1C, alpha 1D and alpha 1G subunits. Pflügers Arch. 1999, 438, 553-560.
9. Hughes, J. R., L. F. Stead & T. Lancaster: Antidepressants for smoking cessation. Cochrane Database Syst. Rev. 2003, 2, CD000031.
10. 2+ increase in human osteosarcoma cells. Pharmacology 2002, 66, 120-127.
11. 2+-activated nonselective cation channel mediating cell membrane depolarization. Cell 2002, 109, 397-407.
12. 2+ entry in MG63 human osteosarcoma cells. Biochem. Pharmacol. 2001, 61, 1537-1541.
13. 2+ movement in human osteosarcoma cells. Pharmacology & Toxicology 2002, 91, 34-39.
14. McFadzean, I. & A. Gibson: The developing relationship between receptor-operated and store-operated calcium channels in smooth muscle. Brit. J. Pharmacol. 2002, 135, 1-13.
15. Merritt, J. E., R. Jocob & T. J. Hallam: Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils. J. Biol. Chem. 1989, 264, 1522-1527.
16. Mitchell, D.B. & D. Acosta: Evaluation of the cytotoxicity of tricyclic antidepressants in primary cultures of rat hepatocytes. J. Toxicol. Environ. Health 1981, 7, 83-92.
17. Punay, N. C. & J. R. Couch: Antidepressants in the treatment of migraine headache. Curr. Pain Headache Rep. 2003, 7, 51-54.
18. Putney, J. W. Jr.: A model for receptor-regulated calcium entry. Cell Calcium 1986, 7, 1-12.
19. Rezzonico, R., C. Cayatte, I. Bourget-Ponzio, G. Romey, N. Belhacene, A. Loubat, S. Rocchi, E. Van Obberghen, J. A. Girault, B. Rossi & H. Scnmid-Antomarchi. Focal adhesion kinase pp!25FAK interacts with the large conductance calcium-activated hSlo potassium channel in human osteoblasts: potential role in mechanotransduction. J. Bone Miner. Res. 2003, 18, 1863-1871.
20. Rizzuto, R., P. Pinton, D. Ferrari, M. Chami, G. Szabadkai, P. J. Magalhaes, F. Di Virgilio & T. Pozzan: Calcium and apoptosis: facts and hypotheses. Oncogene 2003, 22, 8619-8627.
21. Shabnam, G. N., C. Th, D. Kho, R. H. & C. Ce: Therapies for depression in Parkinson's disease. Cochrane Database Syst. Rev. 2003, 3, CD003465.
22. Shin, J. G., J. Y Park, M. J. Kim, J. H. Shon, Y R. Yoon, I. J. Cha, S. S. Lee, S. W. Oh, S. W. Kim & D. A. Flockhart: Inhibitory effects of tricyclic antidepressants (TCAs) on human cytochrome P450 enzymes in vitro: mechanism of drug interaction between TCAs and phenytoin. Drug Metab. Dispos. 2002, 30, 1102-1107.
23. 2+ pump. J. Bioenerg. Biomembr. 2000, 32, 133-142.
24. Strumper, D., M. E. Durieux, M. W. Hollmann, B. Troster, C. G. den Bakker & M. A. Marcus: Effects of antidepressants on function and viability of human neutrophils. Anesthesiology 2003, 98, 1356-1362.
25. Terstappen, G. C., G. Pula, C. Carignani, M. X. Chen & R. Roncarati: Pharmacological characterisation of the human small conductance calcium-activated potassium channel hSK3 reveals sensitivity to tricyclic antidepressants and antipsychotic phenothiazines. Neuropharmacology 2001, 40, 772-783.
26. 2+-ATPase. Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 2466-2470.
27. Thompson, A. K., S. P. Mostafapour, L. C. Denlinger, J. E. Bleasdale & S. K. Fisher: The aminosteroid U73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. J. Biol. Chem. 1991, 266, 23856-23862.
28. Wahlström, A., L. Lenhammar, B. Ask & A. Rane: Tricyclic antidepressants inhibit opioid receptor binding in human brain and hepatic morphine glucuronidation. Pharmacology & Toxicology 1994, 75, 23-27.
29. 2+ mobilization in MG63 human osteosarcoma cells. Harm. Res. 2001, 55, 265-270.
30. Winek C. L., E. M. Morris & W. W. Wahba: The use of bone marrow in the study of postmortem redistribution of nortriptyline. J. Anal. Toxicol. 1993, 17, 93-98.
31. Yasuhara, H., C. A. Dujovne & I. Ueda: Relationship between surface activity and toxicity to Chang liver cultures of tricyclic antidepressants. Pharmacology 1979, 18, 95-102.
32. Zhou, Y., Z. S. Zhou & Z. Q. Zhao: PKC regulates capsaicin-induced currents of dorsal root ganglion neurons in rats. Neuropharmacology 2001, 41, 601-608.