Neuropathy and cognitive impairment following vaccination with the OspA protein of Borrelia burgdorferi

Journal of the Peripheral Nervous System

Volumn 9, Issue 3, 2004, Pages 165-167

  Latov, Norman ^a   Wu, Anita T ^a   Chin, Russell L ^a   Sander, Howard W ^a   Alaedini, Armin ^a   Brannagan III, Thomas H ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Borrelia burgdorferi; Cognitive impairment; Lyme disease; Neuropathy; OspA; Vaccination

Indexed keywords

ALUMINUM HYDROXIDE; BACTERIAL PROTEIN; IMMUNOGLOBULIN; LYME DISEASE VACCINE; OUTER SURFACE PROTEIN A; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOIMMUNITY; BORRELIA BURGDORFERI; CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY; CLINICAL ARTICLE; COGNITIVE DEFECT; FEMALE; HUMAN; LYME DISEASE; MALE; MOTOR NEUROPATHY; NEUROLOGIC DISEASE; NEUROPATHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SENSORY NEUROPATHY; VACCINATION; WHITE MATTER;

ADULT; ANTIGENS, SURFACE; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; BORRELIA BURGDORFERI; COGNITION DISORDERS; FEMALE; HUMANS; LIPOPROTEINS; MALE; MIDDLE AGED; PERIPHERAL NERVOUS SYSTEM DISEASES; POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING; VACCINATION;

EID: 4944220409     PISSN: 10859489     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1085-9489.2004.09306.x     Document Type: Article

References (23)

1. Bsibsi M, Ravid R, Gveric D, van Noort JM (2002). Broad expression of Toll-like receptors in the human central nervous system. J Neuropathol Exp Neurol 61:1013-1021.
2. Bulut Y, Faure E, Thomas L, Equils O, Arditi M (2001). Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. J Immunol 167:987-994.
3. Caudino EA, Coyle PK, Krupp LB (1997). Post-Lyme syndrome and chronic fatigue syndrome. Neuropsychiatric similarities and differences. Arch Neurol 54:1372-1376.
4. Donta ST (2001). Reactivation of Lyme disease following OspA vaccine. Int J Antimicrob Agents 17:5116-S117.
5. Duray PH (1989). Clinical pathologic correlations of Lyme disease. Rev Infect Dis 11:S1487-S1493.
6. Geier DA, Geier M (2002). Lyme vaccination safety. J Spirochetal Tick Borne Dis 8:15-22.
7. Halperin JJ (2003). Lyme disease and the peripheral nervous system. Muscle Nerve 28:133-143.
8. Kindstrand E, Nilsson BY, Hovmark A, Nennesmo I, Pirskanen R, Solders G, Ashbrink E (2000). Polyneuropathy in late Lyme borreliosis - a clinical, neurophysiological and morphological description. Acta Neurol Scand 101:47-52.
9. Krupp LB, Masur D, Schwartz J, Coyle PK, Langenbach LJ, Fernquist SK, Jandorf L, Halperin JJ (1991). Cognitive functioning in late Lyme borreliosis. Arch Neurol 48:1125-1129.
10. Lathrop SL, Ball R, Haber P, Mootrey GT, Braun MM, Shadomy SV, Ellenberg SS, Chen RT, Hays EB (2002). Adverse events reports following vaccination for Lyme disease: December 1998-July 2000. Vaccine 20:1603-1608.
11. Logigian EL (1997). Peripheral nervous system Lyme borreliosis. Semin Neurol 17:25-30.
12. Morgen K, Martin R, Stone RD, Grafman J, Kadom N, McFarland HF, Marques A (2001). FLAIR and magnetization transfer imaging of patients with post-treatment Lyme disease syndrome. Neurology 57:1980-1985.
13. Oey PL, Franssen H, Bernsen RA, Wokke JH (1991). Multifocal conduction block in a patient with Borrelia burgdorferi infection. Muscle Nerve 14:375-377.
14. Oliveira RB, Ochoa MT, Sieling PA, Rea TH, Rambukkana A, Sarno EN, Modlin RL (2003). Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy. Infect Immunol 71:1427-1433.
15. Poser CM (1982). Neurological complications of swine influenza vaccination. Acta Neurol Scand 66:413-431.
16. Ramesh G, Alvarez AL, Roberts ED, Dennis VA, Lasater BL, Alvarez X, Philipp MT (2003). Pathogenesis of Lyme Neuroborreliosis: Borrelia burgdorferi lipoproteins induce both proliferation and apoptosis in rhesus monkey astrocytes. Eur J Immunol 33:2539-2550.
17. Steere AC, Glickstein L (2004). Elucidation of Lyme arthritis. Nat Rev Immunol 4:143-152.
18. Steere AC, Sikand VK, Meurice F, Farenti DL, Fikrig E, Schoen RT, Nowakowski J, Schmid CH, Laukamp S, Buscarino C, Krause DS (1998). Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme disease prevention study group. N Engl J Med 339:209-215.
19. Steiner I (2003). Treating post Lyme disease: trying to solve one equation with too many unknowns. Neurology 60:1888-1889.
20. Tselis AC, Lisak RP (1998). Acute disseminated encephalomyelitis. In: Clinical Neuroimmunology, Ch 9. Antel J, Birnbaum G, Hartung H-P (Eds). Blackwell Science, Inc., Malden, pp 116-147.
21. Vital C, Vital A, Gbikpi-Benissan G, Longy-Boursier M, Climas M-T, Castaing Y, Canron M-H, Le Bras M, Petry K (2002). Postvaccinal inflammatory neuropathy: peripheral nerve biopsy in 3 cases. J Peripher Nerv Syst 7:163-167.
22. Wraith DC, Goldman M, Lambert PH (2003). Vaccination and autoimmune disease: what is the evidence? Lancet 362:1659-1666.
23. Zifko U, Wondrusch E, Machacek E, Grisold W (1995). Inflammatory demyelinating neuropathy in neuroborreliosis. Wien Med Wochenschr 145:188-190.