Bone morphogenetic protein 4 signaling regulates development of the anterior visceral endoderm in the mouse embryo

Development Growth and Differentiation

Volumn 50, Issue 7, 2008, Pages 615-621

  Soares, Miguel L ^a,b   Torres Padilla, Maria Elena ^a,c   Zernicka Goetz, Magdalena ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Anterior visceral endoderm; Anterior posterior axis; Bmp4; Cerberus like; Electroporation; Mouse embryo; RNA interference

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; DOUBLE STRANDED RNA;

ARTICLE; BMP4 GENE; CER1 GENE; CONTROLLED STUDY; ECTODERM; ELECTROPORATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; ENDODERM; GENE; GENE EXPRESSION; MARKER GENE; MOUSE; NIDATION; NONHUMAN; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELLS, CULTURED; EMBRYO, MAMMALIAN; ENDODERM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PREGNANCY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VISCERA;

EID: 49349116339     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/j.1440-169X.2008.01059.x     Document Type: Article

References (25)

1. Beddington, R. S. P. Robertson, E. J. 1998. Anterior patterning in mouse. Trends Gen. 7, 277 284.
2. Beddington, R. S. P. Robertson, E. J. 1999. Axis development and early asymmetry in mammals. Cell 96, 195 209.
3. Calegari, F., Haubensak, W., Yang, D., Huttner, W. B. Buchholz, F. 2002. Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. Proc. Natl Acad. Sci. USA 99, 14 236 14 240.
4. Coucouvanis, E. Martin, G. R. 1999. BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. Development 126, 535 546.
5. Dunn, N. R., Winnier, G. E., Hargett, L. K., Schrick, J. J., Fogo, A. B. Hogan, B. L. 1997. Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4. Dev. Biol. 188, 235 247.
6. Hogan, B. L. 1996. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 10, 1580 1594.
7. Hogan, B. L., Beddington, R., Costantini, F. Lacy, E. 1994. Manipulating the Mouse Embryo, 2nd edn, p. 475. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA.
8. Jones, E. A., Crotty, D., Kulesa, P. M. et al. 2002. Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture. Genesis 34, 228 235.
9. Lawson, K. A., Dunn, N. R., Roelen, B. A. et al. 1999. Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev. 13, 424 436.
10. Mellitzer, G., Hallonet, M., Chen, L. Ang, S. L. 2002. Spatial and temporal 'knock down' of gene expression by electroporation of double-stranded RNA and morpholinos into early postimplantation mouse embryos. Mech. Dev. 118, 57 63.
11. Mesnard, D., Filipe, M., Belo, J. A. Zernicka-Goetz, M. 2004. The anterior-posterior axis emerges respecting the morphology of the mouse embryo that changes and aligns with the uterus before gastrulation. Curr. Biol. 14, 184 196.
12. Perea-Gomez, A., Meilhac, S. M., Piotrowska-Nitsche, K., Gray, D., Collignon, J. Zernicka-Goetz, M. 2007. Regionalization of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder. BMC Dev. Biol. 7, 96.
13. Plusa, B., Frankenberg, S., Chalmers, A. et al. 2005. Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo. J. Cell Sci. 118, 505 515.
14. Richardson, L., Torres-Padilla, M. E. Zernicka-Goetz, M. 2006. Regionalised signalling within the extraembryonic ectoderm regulates anterior visceral endoderm positioning in the mouse embryo. Mech Dev 123, 288 296.
15. Rivera-Pérez, J. A., Mager, J. Magnuson, T. 2003. Dynamic morphogenetic events characterize the mouse visceral endoderm. Dev. Biol. 261, 470 487.
16. Rodriguez, T. A., Srinivas, S., Clements, M. P., Smith, J. C. Beddington, R. S. 2005. Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm. Development 132, 2513 2520.
17. Soares, M. L., Haraguchi, S., Torres-Padilla, M. E. et al. 2005. Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi. BMC Dev. Biol. 5, 28.
18. Srinivas, S., Rodriguez, T., Clements, M., Smith, J. C. Beddington, R. S. 2004. Active cell migration drives the unilateral movements of the anterior visceral endoderm. Development 131, 1157 1164.
19. Svoboda, P., Stein, P., Hayashi, H. Schultz, R. M. 2000. Selective reduction of dormant maternal mRNAs in mouse oocytes by RNAi. Development 127, 4147 4156.
20. Thomas, P. Beddington, R. 1996. Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr. Biol. 6, 1487 1496.
21. Thomas, P. Q., Brown, A. Beddington, R. S. 1998. Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors. Development 125, 85 94.
22. Torres-Padilla, M. E., Richardson, L., Kolasinska, P., Meilhac, S. M., Luetke-Eversloh, M. V. Zernicka-Goetz, M. 2007. The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation. Dev. Biol. 309, 97 112.
23. Wianny, F. Zernicka-Goetz, M. 2000. Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell Biol. 2, 70 75.
24. Wilkinson, D. G., Bhatt, S. Herrmann, B. G. 1990. Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 343, 657 659.
25. Winnier, G., Blessing, M., Labosky, P. A. Hogan, B. L. 1995. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105 2116.