Conditioned flavor avoidance as a measure of withdrawal in rats chronically exposed to a caffeine solution

Physiology and Behavior

Volumn 95, Issue 1-2, 2008, Pages 245-251

  Dreumont Boudreau, Sarah E ^a   Dingle, Rachel N ^a   Alcolado, Gillian M ^a   LoLordo, Vincent M ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Caffeine; Conditioned flavor avoidance; Dependence; Rats; Withdrawal

Indexed keywords

CAFFEINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVOIDANCE BEHAVIOR; CONDITIONING; CONTROLLED STUDY; FLAVOR; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TASTE PREFERENCE; TRAINING;

EID: 49349103489     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2008.06.008     Document Type: Article

References (25)

1. Daly J.W., and Fredholm B.B. Caffeine-an atypical drug of dependence. Drug Alcohol Depend 51 (1998) 199-206
2. Fredholm B.B., Battig K., Holmen J., Nehlig A., and Zvartau E.E. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 51 (1999) 83-133
3. Nehlig A., and Boyet S. Dose-response study of caffeine effects on cerebral functional activity with a specific focus on dependence. Brain Res 858 (2000) 71-77
4. Holtzman S.G. Complete, reversible, drug-specific tolerance to stimulation of locomotor activity by caffeine. Life Sci 33 (1983) 779-787
5. Finn I.B., and Holtzman S.G. Tolerance to caffeine-induced stimulation of locomotor activity in rats. J Pharmacol Exp Ther 238 (1985) 542-546
6. File S.E., Baldwin H.A., Johnston A.L., and Wilks L.J. Behavioral effects of acute and chronic administration of caffeine in the rat. Pharmacol Biochem Behav 30 (1988) 809-815
7. Gasior M.J., Jaszyna M., Peters J., and Goldberg S.R. Changes in the ambulatory activity and discriminative stimulus effects of psychostimulant drugs in rats chronically exposed to caffeine: effect of caffeine dose. J Pharmacol Exp Ther 295 (2000) 1101-1111
8. Meliska C.J., Landrum R.E., and Landrum T.A. Tolerance and sensitization to chronic and subchronic oral caffeine: effects on wheelrunning in rats. Pharmacol Biochem Behav 35 (1990) 477-479
9. Vitiello M.V., and Woods S.C. Evidence for withdrawal from caffeine by rats. Pharmacol Biochem Behav 6 (1977) 553-555
10. Fedorchak P.M., Mesita J., Plater S.A., and Brougham K. Caffeine-reinforced conditioned flavor preferences in rats. Behav Neurosci 116 (2002) 334-346
11. Myers K.P., and Izbicki E.V. Reinforcing and aversive effects of caffeine measured by flavor preference conditioning in caffeine-naïve and caffeine-acclimated rats. Physiol Behav 88 (2006) 585-596
12. Domjan M. Determinants of the enhancement of flavored-water intake by prior exposure. J Exp Psychol Anim Behav Processes 2 (1976) 17-27
13. Dingle R.N., Dreumont-Boudreau S.E., and LoLordo V.M. Caffeine dependence in rats: effects of exposure duration and concentration. Physiol Behav 95 (2008) 252-257 10.1016/j.physbeh.2008.06.007
14. Solomon R.L., and Corbit J.D. The opponent-process theory of motivation. I. Temporal dynamics of affect. Psychol Rev 81 (1974) 119-145
15. Dreumont-Boudreau S.E., and LoLordo V.M. The role of caffeine exposure and dependence in conditioned flavor avoidance. Talk presented at the Annual Associative Learning Symposium, Gregynog, Wales (April 2007)
16. Parker L., Failor A., and Weidman K. Conditioned preferences in the rat with an unnatural need state: Morphine withdrawal. J Comp Physiol Psychol 82 (1973) 294-300
17. Rogers P.J., Richardson N.J., and Elliman N.A. Overnight caffeine abstinence and negative reinforcement of preference for caffeine-containing drinks. Psychopharmacology 120 (1995) 457-462
18. Yeomans M.R., Spetch H., and Rogers P.J. Conditioned flavour preference negatively reinforced by caffeine in human volunteers. Psychopharmacology 137 (1998) 401-409
19. Tinley E.M., Durlach P.J., and Yeomans M.R. How habitual caffeine consumption and dose influence flavour preference conditioning with caffeine. Physiol Behav 82 (2004) 317-324
20. Yeomans M.R., Durlach P.J., and Tinley E.M. Flavour liking and preference conditioned by caffeine in humans. Q J Exp Psychol 58B (2005) 47-58
21. Mobini S., Elliman T.D., and Yeomans M.R. Changes in the pleasantness of caffeine-associated flavours consumed at home. J Food Qual Pref 16 (2005) 659-666
22. Chambers L., Mobini S., and Yeomans M.R. Caffeine deprivation state modulates expression of acquired liking for caffeine-paired flavours. Q J Exp Psychol 60 (2007) 1356-1366
23. Grill H.J., and Norgren R. The taste reactivity test: I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Res 143 (1978) 263-279
24. Schwartz G.J., and Grill H.J. Relationships between taste reactivity and intake in the neurologically intact rat. Chem Senses 9 (1984) 249-272
25. Berridge K.C. Modulation of taste affect by hunger, caloric satiety, and sensory specific satiety in the rat. Appetite 16 (1991) 103-120