The role of omnipause neurons: why glycine?

Progress in Brain Research

Volumn 171, Issue , 2008, Pages 115-121

  Optican, Lance M ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

brainstem; burst neurons; glycine; saccades

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; GLUTAMIC ACID; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER;

AROUSAL; BRAIN FUNCTION; BRAIN STEM; CELL FUNCTION; HEAD MOVEMENT; NERVE CELL; NEUROTRANSMISSION; OMNIDIRECTIONAL PAUSE NEURON; PRIORITY JOURNAL; REVIEW; SACCADIC EYE MOVEMENT;

EID: 49349103304     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(08)00615-8     Document Type: Chapter

References (22)

1. Busettini C., and Mays L.E. Pontine omnipause activity during conjugate and disconjugate eye movements in macaques. J. Neurophysiol. 90 (2003) 3838-3853
2. Buttner-Ennever J.A., Cohen B., Pause M., and Fries W. Raphe nucleus of the pons containing omnipause neurons of the oculomotor system in the monkey, and its homologue in man. J. Comp. Neurol. 267 (1988) 307-321
3. Cohen B., and Henn V. Unit activity in the pontine reticular formation associated with eye movements. Brain Res. 46 (1972) 403-410
4. Dumoulin A., Triller A., and Dieudonne S. IPSC kinetics at identified GABAergic and mixed GABAergic and glycinergic synapses onto cerebellar Golgi cells. J. Neurosci. 21 (2001) 6045-6057
5. Evinger C., Kaneko C.R., and Fuchs A.F. Activity of omnipause neurons in alert cats during saccadic eye movements and visual stimuli. J. Neurophysiol. 47 (1982) 827-844
6. Furuya N., and Markham C.H. Direct inhibitory synaptic linkage of pause neurons with burst inhibitory neurons. Brain Res. 245 (1982) 139-143
7. Harty T.P., and Manis P.B. Kinetic analysis of glycine receptor currents in ventral cochlear nucleus. J. Neurophysiol. 79 (1998) 1891-1901
8. Henn V., Baloh R.W., and Hepp K. The sleep-wake transition in the oculomotor system. Exp. Brain Res. 54 (1984) 166-176
9. Horn A.K., Buttner-Ennever J.A., Wahle P., and Reichenberger I. Neurotransmitter profile of saccadic omnipause neurons in nucleus raphe interpositus. J. Neurosci. 14 (1994) 2032-2046
10. Johnson J.W., and Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325 (1987) 529-531
11. Kaneko C.R. Effect of ibotenic acid lesions of the omnipause neurons on saccadic eye movements in rhesus macaques. J. Neurophysiol. 75 (1996) 2229-2242
12. Keller E.L. Participation of medial pontine reticular formation in eye movement generation in monkey. J. Neurophysiol. 37 (1974) 316-332
13. Langer T.P., and Kaneko C.R. Brainstem afferents to the oculomotor omnipause neurons in monkey. J. Comp. Neurol. 295 (1990) 413-427
14. Luschei E.S., and Fuchs A.F. Activity of brain stem neurons during eye movements of alert monkeys. J. Neurophysiol. 35 (1972) 445-461
15. Missal M., and Keller E.L. Common inhibitory mechanism for saccades and smooth-pursuit eye movements. J. Neurophysiol. 88 (2002) 1880-1892
16. Miura K., and Optican L.M. Membrane channel properties of premotor excitatory burst neurons may underlie saccade slowing after lesions of omnipause neurons. J. Comp. Neurosci. 20 (2006) 25-41
17. Nakao S., Curthoys I.S., and Markham C.H. Direct inhibitory projection of pause neurons to nystagmus-related pontomedullary reticular burst neurons in the cat. Exp. Brain Res. 40 (1980) 283-293
18. Rossi D.J., and Hamann M. Spillover-mediated transmission at inhibitory synapses promoted by high affinity alpha6 subunit GABA(A) receptors and glomerular geometry. Neuron 20 (1998) 783-795
19. Soetedjo R., Kaneko C.R., and Fuchs A.F. Evidence that the superior colliculus participates in the feedback control of saccadic eye movements. J. Neurophysiol. 87 (2002) 679-695
20. Spencer R.F., Wenthold R.J., and Baker R. Evidence for glycine as an inhibitory neurotransmitter of vestibular, reticular, and prepositus hypoglossi neurons that project to the cat abducens nucleus. J. Neurosci. 9 (1989) 2718-2736
21. Strassman A., Evinger C., McCrea R.A., Baker R.G., and Highstein S.M. Anatomy and physiology of intracellularly labelled omnipause neurons in the cat and squirrel monkey. Exp. Brain Res. 67 (1987) 436-440
22. Yoshida K., Iwamoto Y., Chimoto S., and Shimazu H. Saccade-related inhibitory input to pontine omnipause neurons: an intracellular study in alert cats. J. Neurophysiol. 82 (1999) 1198-1208