메뉴 건너뛰기




Volumn 36, Issue 4, 2008, Pages 637-639

The reversal of epigenetic silencing of the EBV genome is regulated by viral bZIP protein

Author keywords

Basic leucine zipper (bZIP); DNA binding; Epigenetics; Methylation; Transcription factor; Virus

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN ALPHA; CYSTEINE; IMMEDIATE EARLY PROTEIN BZLF1; SERINE; TRANSCRIPTION FACTOR AP 1; VIRUS DNA;

EID: 49349094196     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0360637     Document Type: Article
Times cited : (12)

References (32)
  • 1
    • 4944266319 scopus 로고    scopus 로고
    • Epstein-Barr virus: 40 years on
    • Young, L.S. and Rickinson, A.B. (2004) Epstein-Barr virus: 40 years on. Nat. Rev. Cancer 4, 757-768
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 757-768
    • Young, L.S.1    Rickinson, A.B.2
  • 3
    • 0042467687 scopus 로고    scopus 로고
    • Epstein-Barr virus and oncogenesis: From latent genes to tumours
    • Young, L.S. and Murray, P.G. (2003) Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene 22, 5108-5121
    • (2003) Oncogene , vol.22 , pp. 5108-5121
    • Young, L.S.1    Murray, P.G.2
  • 4
    • 85012499638 scopus 로고    scopus 로고
    • Epstein-Barr virus infection: Basis of malignancy and potential for therapy
    • Murray, P.G. and Young, L.S. (2001) Epstein-Barr virus infection: basis of malignancy and potential for therapy. Expert Rev. Mol. Med. 2001, 1-20
    • (2001) Expert Rev. Mol. Med , vol.2001 , pp. 1-20
    • Murray, P.G.1    Young, L.S.2
  • 5
    • 0033610075 scopus 로고    scopus 로고
    • A model for persistent infection with Epstein-Barr virus: The stealth virus of human B cells
    • Thorley-Lawson, D.A. and Babcock, G.J. (1999) A model for persistent infection with Epstein-Barr virus: the stealth virus of human B cells. Life Sci. 65, 1433-1453
    • (1999) Life Sci , vol.65 , pp. 1433-1453
    • Thorley-Lawson, D.A.1    Babcock, G.J.2
  • 6
    • 33748098027 scopus 로고    scopus 로고
    • Epigenotypes of latent herpesvirus genomes
    • Minarovits, J. (2006) Epigenotypes of latent herpesvirus genomes. Curr. Top. Microbiol. Immunol. 310, 61-80
    • (2006) Curr. Top. Microbiol. Immunol , vol.310 , pp. 61-80
    • Minarovits, J.1
  • 7
    • 24744445405 scopus 로고    scopus 로고
    • Epigenetic regulation of lymphoid specific gene sets
    • Gyory, I. and Minarovits, J. (2005) Epigenetic regulation of lymphoid specific gene sets. Biochem. Cell Biol. 83, 286-295
    • (2005) Biochem. Cell Biol , vol.83 , pp. 286-295
    • Gyory, I.1    Minarovits, J.2
  • 8
    • 24344465856 scopus 로고    scopus 로고
    • Epigenetic changes in virus-associated human cancers
    • Li, H.P., Leu, Y.W. and Chang, Y.S. (2005) Epigenetic changes in virus-associated human cancers. Cell Res. 15, 262-271
    • (2005) Cell Res , vol.15 , pp. 262-271
    • Li, H.P.1    Leu, Y.W.2    Chang, Y.S.3
  • 9
    • 0642276399 scopus 로고    scopus 로고
    • Host celldependent expression of latent Epstein-Barr virus genomes: Regulation by DNA methylation
    • Li, H. and Minarovits, J. (2003) Host celldependent expression of latent Epstein-Barr virus genomes: regulation by DNA methylation. Adv. Cancer Res. 89, 133-156
    • (2003) Adv. Cancer Res , vol.89 , pp. 133-156
    • Li, H.1    Minarovits, J.2
  • 10
    • 0142247170 scopus 로고    scopus 로고
    • Stealth technology: How Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection
    • Tao, Q. and Robertson, K.D. (2003) Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection. Clin. Immunol. 109, 53-63
    • (2003) Clin. Immunol , vol.109 , pp. 53-63
    • Tao, Q.1    Robertson, K.D.2
  • 11
    • 0036433743 scopus 로고    scopus 로고
    • Genetic and epigenetic changes in nasopharyngeal carcinoma
    • Lo, K.W. and Huang, D.P. (2002) Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin. Cancer Biol. 12, 451-462
    • (2002) Semin. Cancer Biol , vol.12 , pp. 451-462
    • Lo, K.W.1    Huang, D.P.2
  • 12
    • 0036392058 scopus 로고    scopus 로고
    • Role of genetic and epigenetic changes in Burkitt lymphoma
    • Lindstrom, M.S. and Wiman, K.G. (2002) Role of genetic and epigenetic changes in Burkitt lymphoma. Semin. Cancer Biol. 12, 381-387
    • (2002) Semin. Cancer Biol , vol.12 , pp. 381-387
    • Lindstrom, M.S.1    Wiman, K.G.2
  • 13
    • 0034054838 scopus 로고    scopus 로고
    • The role of DNA methylation in modulating Epstein-Barr virus gene expression
    • Robertson, K.D. (2000) The role of DNA methylation in modulating Epstein-Barr virus gene expression. Curr. Top. Microbiol. Immunol. 249, 21-34
    • (2000) Curr. Top. Microbiol. Immunol , vol.249 , pp. 21-34
    • Robertson, K.D.1
  • 15
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • Klose, R.J. and Bird, A.P. (2006) Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31, 89-97
    • (2006) Trends Biochem. Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 16
    • 0024081657 scopus 로고
    • Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
    • Watt, F. and Molloy, P.L. (1988) Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev. 2, 1136-1143
    • (1988) Genes Dev , vol.2 , pp. 1136-1143
    • Watt, F.1    Molloy, P.L.2
  • 17
    • 33745506986 scopus 로고    scopus 로고
    • Unexpected structure of Epstein-Barr virus lytic cycle activator Zta
    • Sinclair, A.J. (2006) Unexpected structure of Epstein-Barr virus lytic cycle activator Zta. Trends Microbiol. 14, 289-291
    • (2006) Trends Microbiol , vol.14 , pp. 289-291
    • Sinclair, A.J.1
  • 18
    • 0043169617 scopus 로고    scopus 로고
    • bZIP proteins of human gammaherpesviruses
    • Sinclair, A.J. (2003) bZIP proteins of human gammaherpesviruses. J. Gen. Virol. 84, 1941-1949
    • (2003) J. Gen. Virol , vol.84 , pp. 1941-1949
    • Sinclair, A.J.1
  • 19
    • 0026901052 scopus 로고
    • Epstein-Barr virus transcription factors
    • Sinclair, A.J. and Farrell, P.J. (1992) Epstein-Barr virus transcription factors. Cell Growth Differ. 3, 557-563
    • (1992) Cell Growth Differ , vol.3 , pp. 557-563
    • Sinclair, A.J.1    Farrell, P.J.2
  • 20
    • 33645751236 scopus 로고    scopus 로고
    • Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein
    • Morand, P., Budayova-Spano, M., Perrissin, M., Muller, C.W. and Petosa, C. (2006) Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62, 210-214
    • (2006) Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun , vol.62 , pp. 210-214
    • Morand, P.1    Budayova-Spano, M.2    Perrissin, M.3    Muller, C.W.4    Petosa, C.5
  • 21
    • 32444448106 scopus 로고    scopus 로고
    • Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein
    • Petosa, C., Morand, P., Baudin, F., Moulin, M., Artero, J.B. and Muller, C.W. (2006) Structural basis of lytic cycle activation by the Epstein-Barr virus ZEBRA protein. Mol. Cell 21, 565-572
    • (2006) Mol. Cell , vol.21 , pp. 565-572
    • Petosa, C.1    Morand, P.2    Baudin, F.3    Moulin, M.4    Artero, J.B.5    Muller, C.W.6
  • 22
    • 34250889238 scopus 로고    scopus 로고
    • Atypical bZIP domain of viral transcription factor contributes to stability of dimer formation and transcriptional function
    • Schelcher, C., Al Mehairi, S., Verrall, E., Hope, Q., Flower, K., Bromley, B., Woolfson, D.N., West, M.J. and Sinclair, A.J. (2007) Atypical bZIP domain of viral transcription factor contributes to stability of dimer formation and transcriptional function. J. Virol. 81, 7149-7155
    • (2007) J. Virol , vol.81 , pp. 7149-7155
    • Schelcher, C.1    Al Mehairi, S.2    Verrall, E.3    Hope, Q.4    Flower, K.5    Bromley, B.6    Woolfson, D.N.7    West, M.J.8    Sinclair, A.J.9
  • 23
    • 0035038931 scopus 로고    scopus 로고
    • Biophysical analysis of natural variants of the multimerization region of Epstein-Barr virus lytic-switch protein BZLF1
    • Hicks, M.R., Balesaria, S., Medina-Palazon, C., Pandya, M.J., Woolfson, D.N. and Sinclair, A.J. (2001) Biophysical analysis of natural variants of the multimerization region of Epstein-Barr virus lytic-switch protein BZLF1. J. Virol. 75, 5381-5384
    • (2001) J. Virol , vol.75 , pp. 5381-5384
    • Hicks, M.R.1    Balesaria, S.2    Medina-Palazon, C.3    Pandya, M.J.4    Woolfson, D.N.5    Sinclair, A.J.6
  • 24
    • 0038420735 scopus 로고    scopus 로고
    • The zipper region of Epstein-Barr virus bZIP transcription factor Zta is necessary but not sufficient to direct DNA binding
    • Hicks, M.R., Al-Mehairi, S.S. and Sinclair, AJ. (2003) The zipper region of Epstein-Barr virus bZIP transcription factor Zta is necessary but not sufficient to direct DNA binding. J. Virol. 77, 8173-8177
    • (2003) J. Virol , vol.77 , pp. 8173-8177
    • Hicks, M.R.1    Al-Mehairi, S.S.2    Sinclair, A.J.3
  • 25
    • 0026163624 scopus 로고
    • Pathways of activation of the Epstein-Barr virus productive cycle
    • Sinclair, A.J., Brimmell, M., Shanahan, F. and Farrell, P.J. (1991) Pathways of activation of the Epstein-Barr virus productive cycle, J. Virol. 65, 2237-2244
    • (1991) J. Virol , vol.65 , pp. 2237-2244
    • Sinclair, A.J.1    Brimmell, M.2    Shanahan, F.3    Farrell, P.J.4
  • 26
    • 0034660443 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic program is controlled by the co-operative functions of two tfansactivators
    • Feederle, R., Kost, M., Baumann, M., Janz, A., Drouet, E., Hammerschmidt, W. and Delecluse, H.J. (2000) The Epstein-Barr virus lytic program is controlled by the co-operative functions of two tfansactivators. EMBO J. 19, 3080-3039
    • (2000) EMBO J , vol.19 , pp. 3080-3039
    • Feederle, R.1    Kost, M.2    Baumann, M.3    Janz, A.4    Drouet, E.5    Hammerschmidt, W.6    Delecluse, H.J.7
  • 27
    • 33645751236 scopus 로고    scopus 로고
    • Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein
    • Morand, P., Budayova-Spano, M., Perrissin, M., Muller, C.W. and Petosa, C (2006) Expression, purification, crystallization and preliminary X-ray analysis of a C-terminal fragment of the Epstein-Barr virus ZEBRA protein. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62, 210-214
    • (2006) Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun , vol.62 , pp. 210-214
    • Morand, P.1    Budayova-Spano, M.2    Perrissin, M.3    Muller, C.W.4    Petosa, C.5
  • 28
    • 6944244957 scopus 로고    scopus 로고
    • The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome
    • Bhende, P.M., Seaman, W.T., Delecluse, H.J. and Kenney, S.C. (2004) The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome. Nat. Genet. 36, 1099-1104
    • (2004) Nat. Genet , vol.36 , pp. 1099-1104
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.J.3    Kenney, S.C.4
  • 29
    • 19944397140 scopus 로고    scopus 로고
    • BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186
    • Bhende, P.M., Seaman, W.T., Delecluse, H.J. and Kenney, S.C. (2005) BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. J. Virol. 79, 7338-7348
    • (2005) J. Virol , vol.79 , pp. 7338-7348
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.J.3    Kenney, S.C.4
  • 30
    • 27144531199 scopus 로고    scopus 로고
    • A redox-sensitive cysteine in Zta is required for Epstein-Barr virus lytic cycle DNA replication
    • Wang, P., Day, L., Dheekollu, J. and Lieberman, P.M. (2005) A redox-sensitive cysteine in Zta is required for Epstein-Barr virus lytic cycle DNA replication. J. Virol. 79, 13298-13309
    • (2005) J. Virol , vol.79 , pp. 13298-13309
    • Wang, P.1    Day, L.2    Dheekollu, J.3    Lieberman, P.M.4
  • 31
    • 42949174160 scopus 로고    scopus 로고
    • Karlsson, Q.H., Schelcher, C., Verrall, E., Petosa, C. and Sinclair, A.J. (2008) Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein. PLoS Pathog. 4, e1000005
    • Karlsson, Q.H., Schelcher, C., Verrall, E., Petosa, C. and Sinclair, A.J. (2008) Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein. PLoS Pathog. 4, e1000005
  • 32
    • 27144458370 scopus 로고    scopus 로고
    • Mutation of a single amino acid residue in the basic region of the Epstein-Barr virus (EBV) lytic cycle switch protein Zta (BZLF1) prevents reactivation of EBV from latency
    • Schelcher, C., Valencia, S., Delecluse, H.J., Hicks, M. and Sinclair, A.J. (2005) Mutation of a single amino acid residue in the basic region of the Epstein-Barr virus (EBV) lytic cycle switch protein Zta (BZLF1) prevents reactivation of EBV from latency. J. Virol. 79, 13822-13828
    • (2005) J. Virol , vol.79 , pp. 13822-13828
    • Schelcher, C.1    Valencia, S.2    Delecluse, H.J.3    Hicks, M.4    Sinclair, A.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.