Efficacy and tolerance of metronidazole and miconazole nitrate in treatment of vaginitis

International Journal of Gynecology and Obstetrics

Volumn 102, Issue 3, 2008, Pages 287-292

  Peixoto, Fabio ^a   Camargos, Aroldo ^a   Duarte, Geraldo ^b   Linhares, Iara ^b   Bahamondes, Luis ^c   Petracco, Alvaro ^d  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

^d PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Bacterial vaginosis; Metronidazole; Miconazole; Trichomonal vaginitis; Vulvovaginal candidiasis

Indexed keywords

METRONIDAZOLE; MICONAZOLE NITRATE;

ADULT; ARTICLE; CANDIDA ALBICANS; DRUG EFFICACY; DRUG TOLERABILITY; DYSMENORRHEA; FEMALE; FUNGUS CULTURE; GARDNERELLA VAGINALIS; GYNECOLOGY; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MCNEMAR TEST; MICROBIOLOGY; MICROSCOPY; PRIORITY JOURNAL; UTERINE CERVIX CYTOLOGY; VAGINA DISCHARGE; VAGINA PESSARY; VAGINA SMEAR; VAGINAL BURNING SENSATION; VAGINITIS;

EID: 49349093183     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijgo.2008.04.014     Document Type: Article

References (26)

1. ACOG Committee on Practice Bulletins-Gynecology. ACOG Practice Bulletin. Clinical management guidelines for obstetrician-gynecologists, Number 72, May 2006: Vaginitis. Obstet Gynecol 107 5 (2006) 1195-1206
2. Kent H.L. Epidemiology of vaginitis. Am J Obstet Gynecol 165 4 (1991) 1168-1176
3. Giraldo P.C., Ribeiro-Filho A.D., Simões J.A., Gomes F.A.M., and Magalhães J. Vulvovaginites - Aspectos habitualmente não considerados. J Bras Ginecol 107 4 (1997) 89-93
4. Egan M.E., and Lipsky M.S. Diagnosis of vaginitis. Am Fam Physician 62 5 (2000) 1095-1104
5. Anderson M.R., Klink K., and Cohrssen A. Evaluation of vaginal complaints. JAMA 291 11 (2004) 1368-1379
6. Mitchell H. Vaginal discharge-causes, diagnosis, and treatment. BMJ 328 7451 (2004) 1306-1308
7. Sexually Transmitted Diseases Treatment Guidelines. Center for Disease Control and Prevention MMWR Recomm Rep 2002; 51 (RR06) (2002) 1-80. http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5106a1.htm http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5106a1.htm. Accessed May 29, 2006
8. Sobel J.D. What's new in bacterial vaginosis and trichomoniasis?. Infect Dis Clin North Am 19 2 (2005) 387-406
9. Soper D. Trichomoniasis: under control or undercontrolled?. Am J Obstet Gynecol 190 1 (2004) 281-290
10. Goldenberg R.L., Mwatha A., Read J.S., Adeniyi-Jones S., Sinkala M., Msmanga G., et al. The HPTN 024 Study: the efficacy of antibiotics to prevent chorioamnionitis and preterm birth. Am J Obstet Gynecol 194 3 (2006) 650-661
11. Schaaf V.M., Perez-Stable E.J., and Borchardt K. The limited value of symptoms and signs in the diagnosis of vaginal infections. Arch Intern Med 150 9 (1990) 1929-1933
12. Landers D.V., Wiesenfeld H.C., Heine R.P., Krohn M.A., and Hillier S.L. Predictive value of the clinical diagnosis of lower genital tract infection in women. Am J Obstet Gynecol 190 4 (2004) 1004-1010
13. Özyurt E., Toykuliyeva M.B., Danilyans I.L., Morton O., and Baktir G. Efficacy of 7-day treatment with metronidazole + miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections. Int J Gynecol Obstet 74 1 (2001) 35-43
14. Kükner S., Ergin T., Ciçek N., Ugur M., Yeşilyurt H., and Gökmen O. Treatment of vaginitis. Int J Gynecol Obstet 52 1 (1996) 43-47
15. Morton O. Neotran-a new double-active pessary for the treatment of vaginitis. J Int Med Res 21 1 (1993) 36-46
16. Upmalis D.H., Cone F.l., Lamia C.A., Reisman H., Rodriguez-Gomez G., Gilderman L., et al. Single-dose miconazole nitrate vaginal ovule in the treatment of vulvovaginal candidiasis: two single-blind, controlled studies versus miconazole nitrate 100 mg cream for 7 days. J Womens Health Gend Based Med 9 4 (2000) 421-429
17. Emele F.E., Fadahunsi A.A., Anyiwo C.E., and Ogunleye O. A comparative clinical evaluation of econazole nitrate, miconazole and nystatin in the treatment of vaginal candidiasis. West Afr J Med 19 1 (2000) 12-15
18. Brown D., Henzl M.R., and Kaufman R.H. Butoconazole nitrate 2% for vulvovaginal candidiasis. New, single dose vaginal cream formulation vs. seven-day treatment with miconazole nitrate. Gynazole 1 Study Group. J Reprod Med 44 11 (1999) 933-938
19. Owen M.K., and Clenney T.L. Management of vaginitis. Am Fam Physician 70 11 (2004) 2125-2132
20. Amsel R., Totten P.A., Spiegel C.A., Chen K.C., Eschenbach D., and Holmes K.K. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 74 1 (1983) 14-22
21. Joesoef M.R., Schmid G.P., and Hillier S.L. Bacterial vaginosis: a review of treatment options and potential clinical indications for therapy. Clin Infect Dis 28 Suppl 1 (1999) S57-S65
22. Wilson J. Managing recurrent bacterial vaginosis. Sex Transm Infect 80 1 (2004) 8-11
23. Hillier S.L. Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol 169 2 (1993) 455-459
24. Edwards L. The diagnosis and treatment of infectious vaginitis. Dermatol Ther 17 1 (2004) 102-110
25. Hanson J.M., McGregor J.A., Hillier S.L., Eschenbach D.A., Kreutner A.K., Galask R.P., et al. Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs. oral therapy. J Reprod Med 45 11 (2000) 889-896
26. Sobel J.D., Ferris D., Schwebke J., Nyirjesy P., Wiesenfeld H.C., Peipert J., et al. Suppressive antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosis. Am J Obstet Gynecol 194 5 (2006) 1283-1289