A framework to investigate drug release variability arising from hypromellose viscosity specifications in controlled release matrix tablets

Journal of Pharmaceutical Sciences

Volumn 97, Issue 6, 2008, Pages 2277-2285

  Mitchell, Shawn A ^a   Balwinski, Karen M ^a  

^a DOW CHEMICAL COMPANY   (United States)

Author keywords

Controlled release; HPMC; Hypromellose; Matrix system; Molecular weight; Viscosity

Indexed keywords

HYDROCHLOROTHIAZIDE; HYDROXYPROPYLMETHYLCELLULOSE; PENTOXIFYLLINE; THEOPHYLLINE; DRUG; DRUG CARRIER; DRUG DERIVATIVE; LACTOSE; METHYLCELLULOSE;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG FORMULATION; MATRIX TABLET; MOLECULAR WEIGHT; PARTICLE SIZE; PREDICTION; VISCOSITY; CHEMICAL MODEL; CHEMISTRY; DELAYED RELEASE FORMULATION; KINETICS; METHODOLOGY; PHARMACEUTICS; SOLUBILITY; TABLET;

CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; HYDROCHLOROTHIAZIDE; KINETICS; LACTOSE; METHYLCELLULOSE; MODELS, CHEMICAL; MOLECULAR WEIGHT; PENTOXIFYLLINE; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL; THEOPHYLLINE; VISCOSITY;

EID: 49249127258     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21145     Document Type: Article

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