Probiotic prophylaxis in patients with predicted severe acute pancreatitis: A randomised, double-blind, placebo-controlled trial;Probioticaprofylaxe bij voorspeld ernstige acute pancreatitis; gerandomiseerde, dubbelblinde, placebogecontroleerde trial en informed-consentprocedure

Nederlands Tijdschrift voor Geneeskunde

Volumn 152, Issue 28, 2008, Pages 1593-1594

  Besselink, M G H ^a   Van Santvoort, H C ^a   Buskens, E ^a   Boermeester, M A ^a   Akkermans, L M A ^a   Gooszen, H G ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROBIOTIC AGENT;

ACUTE PANCREATITIS; CLINICAL TRIAL; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; FALSE POSITIVE RESULT; HUMAN; INCIDENCE; LETTER; MORTALITY; RANDOMIZED CONTROLLED TRIAL; TREATMENT INDICATION; TREATMENT RESPONSE;

EID: 49149119544     PISSN: 00282162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (9)

1. Vandenbroucke JP. Dwalingen in de methodologie. XIV. Het voortijdig beëindigen van een gerandomiseerde trial. Ned Tijdschr Geneeskd. 1999;143:1305-8.
2. Banks PA, Freeman ML. Practice guidelines in acute pancreatitis. Am J Gastroenterol. 2006;101:2379-400.
3. Isenmann R, Rünzi M, Kron M, Kahl S, Kraus D, Jung N, et al. Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial. Gastroenterology. 2004;126:997-1004.
4. Oláh A, Belágyi T, Issekutz A, Gamal ME, Bengmark S. Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis. Br J Surg. 2002;89:1103-7.
5. Oláh A, Belágyi T, Pótó L, Romics jr L, Bengmark S. Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double blind study. Hepatogastroenterology. 2007;54:590-4.
6. Besselink MG, Timmerman HM, Buskens E, Nieuwenhuijs VB, Akkermans LM, Gooszen HG. Probiotic prophylaxis in patients with predicted severe acute pancreatitis (PROPATRIA): design and rationale of a double-blind, placebo-controlled randomised multicenter trial [ISRCTN38327949]. Dutch Acute Pancreatitis Study Group. BMC Surg. 2004;4:12.
7. Besselink MG, Santvoort HC van, Buskens E, Boermeester MA, Goor H van, Timmerman HM, et al. Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet. 2008;371:651-9.
8. DAMOCLES Study Group, NHS Health Technology Assessment Programme. A proposed charter for clinical trial data monitoring committees: helping them to do their job well. Lancet. 2005;365:711-22.
9. Grant AM, Altman DG, Babiker AB, Campbell MK, Clemens FJ, Darbyshire JH, et al. Issues in data monitoring and interim analysis of trials. Health Technol Assess. 2005;9:1-238, iii-iv.