-
1
-
-
0019388174
-
Mechanisms of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: Evidence for the involvement of S-nitrosothiols as active intermediates
-
Ignarro LJ, Lipton H, Edwards JC, Baricos WH, Hyman AL, Kadowitz PJ, Gruetter CA (1981) Mechanisms of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: Evidence for the involvement of S-nitrosothiols as active intermediates. J Pharmacol Exp Ther 218:739-749
-
(1981)
J Pharmacol Exp Ther
, vol.218
, pp. 739-749
-
-
Ignarro, L.J.1
Lipton, H.2
Edwards, J.C.3
Baricos, W.H.4
Hyman, A.L.5
Kadowitz, P.J.6
Gruetter, C.A.7
-
2
-
-
0025784834
-
Endogenous nitric oxide: Physiology, pathology and clinical relevance
-
Moncada S, Higgs EA (1991) Endogenous nitric oxide: Physiology, pathology and clinical relevance. Eur J Clin Invest 21:361-374
-
(1991)
Eur J Clin Invest
, vol.21
, pp. 361-374
-
-
Moncada, S.1
Higgs, E.A.2
-
3
-
-
0029797623
-
Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs
-
Iversen HK, Olesen J (1996) Headache induced by a nitric oxide donor (nitroglycerin) responds to sumatriptan. A human model for development of migraine drugs. Cephalalgia 16:412-418
-
(1996)
Cephalalgia
, vol.16
, pp. 412-418
-
-
Iversen, H.K.1
Olesen, J.2
-
4
-
-
0026604873
-
Dose-dependent headache response and dilatation of limb and extracranial arteries after three doses of 5-isosorbide-mononitrate
-
Iversen HK, Nielsen TH, Garre K, Tfelt-Hansen P, Olesen J (1992) Dose-dependent headache response and dilatation of limb and extracranial arteries after three doses of 5-isosorbide-mononitrate. Eur J Clin Pharmacol 42:31-35
-
(1992)
Eur J Clin Pharmacol
, vol.42
, pp. 31-35
-
-
Iversen, H.K.1
Nielsen, T.H.2
Garre, K.3
Tfelt-Hansen, P.4
Olesen, J.5
-
5
-
-
0028360745
-
Nitric oxide is a key molecule in migraine and other vascular headaches
-
Olesen J, Thomsen LL, Iversen HK (1994) Nitric oxide is a key molecule in migraine and other vascular headaches. Trends Pharmacol Sci 15:149-153
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 149-153
-
-
Olesen, J.1
Thomsen, L.L.2
Iversen, H.K.3
-
6
-
-
0023932439
-
Quality of life on angina therapy: A randomized controlled trial of transdermal glyceryl trinitrate against placebo
-
Fletcher A, McLoone P, Bulpitt C (1988) Quality of life on angina therapy: A randomized controlled trial of transdermal glyceryl trinitrate against placebo. Lancet 2(8601):4-8
-
(1988)
Lancet
, vol.2
, Issue.8601
, pp. 4-8
-
-
Fletcher, A.1
McLoone, P.2
Bulpitt, C.3
-
7
-
-
0034454657
-
Headache characteristics during the development of tolerance to nitrites. Pathophysiological implications
-
Christiansen I, Iversen HK, Olesen J (2002) Headache characteristics during the development of tolerance to nitrites. Pathophysiological implications. Cephalalgia 20:437-444
-
(2002)
Cephalalgia
, vol.20
, pp. 437-444
-
-
Christiansen, I.1
Iversen, H.K.2
Olesen, J.3
-
8
-
-
0020394689
-
Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries
-
Aaslid R, Markwalder TM, Nomes H (1982) Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57:769-774
-
(1982)
J Neurosurg
, vol.57
, pp. 769-774
-
-
Aaslid, R.1
Markwalder, T.M.2
Nomes, H.3
-
9
-
-
0027768938
-
Experimental and biological variation of three-dimensional transcranial Doppler measurements
-
Thomsen LL, Iversen HK (1993) Experimental and biological variation of three-dimensional transcranial Doppler measurements. J Appl Physiol 75:2805-2810
-
(1993)
J Appl Physiol
, vol.75
, pp. 2805-2810
-
-
Thomsen, L.L.1
Iversen, H.K.2
-
10
-
-
0027740215
-
Small arteries can be accurately studied in-vivo, using high frequency ultrasound
-
Nielsen TH, Iversen HK, Tfelt-Hansen P, Olesen J (1993) Small arteries can be accurately studied in-vivo, using high frequency ultrasound. Ultrasound Med Biol 19:717-725
-
(1993)
Ultrasound Med Biol
, vol.19
, pp. 717-725
-
-
Nielsen, T.H.1
Iversen, H.K.2
Tfelt-Hansen, P.3
Olesen, J.4
-
11
-
-
0025677260
-
Determination of the luminal diameter of the radial artery in man by high frequency ultrasound: A methodological study
-
Nielsen TH, Iversen HK, Tfelt-Hansen P (1990) Determination of the luminal diameter of the radial artery in man by high frequency ultrasound: A methodological study. Ultrasound Med Biol 16:789-791
-
(1990)
Ultrasound Med Biol
, vol.16
, pp. 789-791
-
-
Nielsen, T.H.1
Iversen, H.K.2
Tfelt-Hansen, P.3
-
13
-
-
26244465889
-
Explaining the phenomenon of nitrate tolerance
-
Münzel T, Daiber A, Mülsch A (2005) Explaining the phenomenon of nitrate tolerance. Circ Res 97:618-628
-
(2005)
Circ Res
, vol.97
, pp. 618-628
-
-
Münzel, T.1
Daiber, A.2
Mülsch, A.3
-
14
-
-
0019819716
-
Isosorbide 5-mononitrate pharmacokinetics in humans
-
Taylor T, Chasseaud LF, Major R, Doyle E, Darragh A (1981) Isosorbide 5-mononitrate pharmacokinetics in humans. Biopharm Drug Dispos 2:255-263
-
(1981)
Biopharm Drug Dispos
, vol.2
, pp. 255-263
-
-
Taylor, T.1
Chasseaud, L.F.2
Major, R.3
Doyle, E.4
Darragh, A.5
-
15
-
-
0021165009
-
Isosorbide 5-mononitrate kinetics
-
Major RM, Taylor T, Chasseaud LF, Darragh A, Lambe RF (1984) Isosorbide 5-mononitrate kinetics. Clin Pharmacol Ther 35:653-659
-
(1984)
Clin Pharmacol Ther
, vol.35
, pp. 653-659
-
-
Major, R.M.1
Taylor, T.2
Chasseaud, L.F.3
Darragh, A.4
Lambe, R.F.5
-
16
-
-
0025344305
-
Relationship between pharmacokinetics and hemodynamic tolerance to isosorbide-5-mononitrate
-
Wagner F, Siefert F, Trenk D, Jänchen E (1990) Relationship between pharmacokinetics and hemodynamic tolerance to isosorbide-5-mononitrate. Eur J Clin Pharmacol 38(Suppl 1):S53-S59
-
(1990)
Eur J Clin Pharmacol
, vol.38
, Issue.SUPPL. 1
-
-
Wagner, F.1
Siefert, F.2
Trenk, D.3
Jänchen, E.4
-
17
-
-
0024815241
-
Effect of nitroglycerin on cerebral circulation measured by transcranial Doppler and SPECT
-
Dahl A, Russell D, Nyberg-Hansen R, Rootwell K (1989) Effect of nitroglycerin on cerebral circulation measured by transcranial Doppler and SPECT. Stroke 20:173-176
-
(1989)
Stroke
, vol.20
, pp. 173-176
-
-
Dahl, A.1
Russell, D.2
Nyberg-Hansen, R.3
Rootwell, K.4
-
19
-
-
0034283154
-
The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man
-
White RP, Deane C, Hindley C, Bloomfield PM, Cunningham VJ, Vallance P et al (2000) The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man. J Neurol Sci 178:23-28
-
(2000)
J Neurol Sci
, vol.178
, pp. 23-28
-
-
White, R.P.1
Deane, C.2
Hindley, C.3
Bloomfield, P.M.4
Cunningham, V.J.5
Vallance, P.6
-
20
-
-
0036835063
-
Brain blood flow in the nitroglycerin (GTN) model of migraine: Measurement using positron emision tomography and transcranial Doppler
-
Bednarczyk EM, Wack DS, Kassab MY, Burch K, Trinidad K, Haka M, Gona J (2002) Brain blood flow in the nitroglycerin (GTN) model of migraine: measurement using positron emision tomography and transcranial Doppler. Cephalalgia 22:749-757
-
(2002)
Cephalalgia
, vol.22
, pp. 749-757
-
-
Bednarczyk, E.M.1
Wack, D.S.2
Kassab, M.Y.3
Burch, K.4
Trinidad, K.5
Haka, M.6
Gona, J.7
-
21
-
-
0025765727
-
Migraine pain associated with middle cerebral artery dilatation: Reversal by sumatriptan
-
Friberg L, Olesen J, Iversen HK, Sperling B (1991) Migraine pain associated with middle cerebral artery dilatation: Reversal by sumatriptan. Lancet 338:13-17
-
(1991)
Lancet
, vol.338
, pp. 13-17
-
-
Friberg, L.1
Olesen, J.2
Iversen, H.K.3
Sperling, B.4
-
22
-
-
0027732009
-
Arterial supersensitivity to nitric oxide (nitroglycerin) in migraine sufferers
-
Thomsen LL, Iversen HK, Brinck TA, Olesen J (1993) Arterial supersensitivity to nitric oxide (nitroglycerin) in migraine sufferers. Cephalalgia 13:395-399
-
(1993)
Cephalalgia
, vol.13
, pp. 395-399
-
-
Thomsen, L.L.1
Iversen, H.K.2
Brinck, T.A.3
Olesen, J.4
-
23
-
-
0029977893
-
Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model
-
Schmetterer L, Woltz M, Krejcy K, Graselli U, Findl O, Eichler HG, Singer EA (1996) Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model. Clin Pharmacol Ther 60:199-205
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 199-205
-
-
Schmetterer, L.1
Woltz, M.2
Krejcy, K.3
Graselli, U.4
Findl, O.5
Eichler, H.G.6
Singer, E.A.7
-
24
-
-
0034846916
-
Differential effects of pentaerythritol tetranitrate and nitroglycerin on the delopment of tolerance and evidence: A human in vivo study
-
Jurt U, Gori T, Ravandi A, Babaei S, Zeman P, Parker JD (2001) Differential effects of pentaerythritol tetranitrate and nitroglycerin on the delopment of tolerance and evidence: A human in vivo study. J Am Coll Cardiol 38:854-859
-
(2001)
J Am Coll Cardiol
, vol.38
, pp. 854-859
-
-
Jurt, U.1
Gori, T.2
Ravandi, A.3
Babaei, S.4
Zeman, P.5
Parker, J.D.6
-
25
-
-
0027402588
-
Lack of tolerance of headache and radial artery diameter during a 7 hour intravenous infusion of nitroglycerin
-
Iversen HK, Nielsen TH, Tfelt-Hansen P, Olesen J (1993) Lack of tolerance of headache and radial artery diameter during a 7 hour intravenous infusion of nitroglycerin. Eur J Clin Pharmacol 44:47-50
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 47-50
-
-
Iversen, H.K.1
Nielsen, T.H.2
Tfelt-Hansen, P.3
Olesen, J.4
-
26
-
-
0028157603
-
Altered peripheral vasodilatory profile of nitroglycerin during long-term infusion of N-acetylcystein
-
Boesgaard S, Iversen H, Wroblewski H, Poulsen HE, Frandsen H, Kastrup J, Aldershvile J (1994) Altered peripheral vasodilatory profile of nitroglycerin during long-term infusion of N-acetylcystein. J Am Coll Cardiol 23:163-169
-
(1994)
J Am Coll Cardiol
, vol.23
, pp. 163-169
-
-
Boesgaard, S.1
Iversen, H.2
Wroblewski, H.3
Poulsen, H.E.4
Frandsen, H.5
Kastrup, J.6
Aldershvile, J.7
-
27
-
-
0029056387
-
Absence of vascular tolerance in conductance vessels after 48 hours of intravenous nitroglycerin in patients with coronary artery disease
-
Jeserich M, Münzel T, Pape L, Fischer C, Drexler H, Just H (1995) Absence of vascular tolerance in conductance vessels after 48 hours of intravenous nitroglycerin in patients with coronary artery disease. J Am Coll Cardiol 26:50-56
-
(1995)
J Am Coll Cardiol
, vol.26
, pp. 50-56
-
-
Jeserich, M.1
Münzel, T.2
Pape, L.3
Fischer, C.4
Drexler, H.5
Just, H.6
-
28
-
-
0028318885
-
Tolerance to nitroglycerin in vascular smooth muscle cells: Recovery and cross-tolerance to sodium nitroprusside
-
Zhang LM, Castresana MR, Newman WH (1994) Tolerance to nitroglycerin in vascular smooth muscle cells: Recovery and cross-tolerance to sodium nitroprusside. Anesth Analg 78:1053-1059
-
(1994)
Anesth Analg
, vol.78
, pp. 1053-1059
-
-
Zhang, L.M.1
Castresana, M.R.2
Newman, W.H.3
-
29
-
-
0031023122
-
Response of cultured cerebral artery smooth muscle cells to the nitric oxide vasodilator, nitroglycerin and sodium nitroprusside
-
Tao H, Zhang LM, Castresana MR, Newman WH, Shillcutt SD (1997) Response of cultured cerebral artery smooth muscle cells to the nitric oxide vasodilator, nitroglycerin and sodium nitroprusside. J Neurosurg Anesth 1:58-64
-
(1997)
J Neurosurg Anesth
, vol.1
, pp. 58-64
-
-
Tao, H.1
Zhang, L.M.2
Castresana, M.R.3
Newman, W.H.4
Shillcutt, S.D.5
-
30
-
-
0025912301
-
Tolerance to organic nitrates: Evidence, mechanisms, clinical relevance and strategies for prevention
-
Elkayam U (1991) Tolerance to organic nitrates: Evidence, mechanisms, clinical relevance and strategies for prevention. Ann Int Med 114:667-677
-
(1991)
Ann Int Med
, vol.114
, pp. 667-677
-
-
Elkayam, U.1
-
31
-
-
0028799761
-
Evidence for enhanced vascular superoxide anion production in nitrate tolerance: A novel mechanism of tolerance and cross tolerance
-
Münzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG (1995) Evidence for enhanced vascular superoxide anion production in nitrate tolerance: A novel mechanism of tolerance and cross tolerance. J Clin Invest 95:187-194
-
(1995)
J Clin Invest
, vol.95
, pp. 187-194
-
-
Münzel, T.1
Sayegh, H.2
Freeman, B.A.3
Tarpey, M.M.4
Harrison, D.G.5
-
32
-
-
0029063158
-
Evidence for a role of endothelin-1 and protein kinase C in nitrate tolerance
-
Münzel T, Giaid A, Kurz S, Stewart D, Harrison D (1995) Evidence for a role of endothelin-1 and protein kinase C in nitrate tolerance. Proc Natl Acad Sci USA 92:5244-5248
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5244-5248
-
-
Münzel, T.1
Giaid, A.2
Kurz, S.3
Stewart, D.4
Harrison, D.5
-
33
-
-
34249746904
-
Increased superoxide production in nitrate tolerance is associated with NAD(P) H oxidase and aldehyde dehydrogenase 2 downregulation
-
Szöcs K, Lasseque B, Wenzel P, Wendt M, Daiber A, Oelze M, Meinertz T, Münzel T, Baldus S (2007) Increased superoxide production in nitrate tolerance is associated with NAD(P) H oxidase and aldehyde dehydrogenase 2 downregulation. J Mol Cell Cardiol 42:1111-1118
-
(2007)
J Mol Cell Cardiol
, vol.42
, pp. 1111-1118
-
-
Szöcs, K.1
Lasseque, B.2
Wenzel, P.3
Wendt, M.4
Daiber, A.5
Oelze, M.6
Meinertz, T.7
Münzel, T.8
Baldus, S.9
-
34
-
-
0025747926
-
Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin
-
Parker JD, Farrell B, Fenton T, Cohanim M, Parker JO (1991) Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin. Circulation 84:2336-2345
-
(1991)
Circulation
, vol.84
, pp. 2336-2345
-
-
Parker, J.D.1
Farrell, B.2
Fenton, T.3
Cohanim, M.4
Parker, J.O.5
-
35
-
-
34548027086
-
Decrease in endogenous CGRP release in nitroglycerin tolerance: Role of ALDH-2
-
Chen YR, Nie SD, Shan W, Jiang DJ, Shi RZ, Zhou Z et al (2007) Decrease in endogenous CGRP release in nitroglycerin tolerance: Role of ALDH-2. Eur J Pharmacol 571:44-50
-
(2007)
Eur J Pharmacol
, vol.571
, pp. 44-50
-
-
Chen, Y.R.1
Nie, S.D.2
Shan, W.3
Jiang, D.J.4
Shi, R.Z.5
Zhou, Z.6
-
36
-
-
9444221430
-
Oxidative stress and mitochondrial aldehyde dehydrogenase activity: A comparison of pentaerythritol with other organic nitrates
-
Daiber A, Oelze M, Coldeway M, Bachsmid M, Wenzel P, Sydow K et al (2004) Oxidative stress and mitochondrial aldehyde dehydrogenase activity: A comparison of pentaerythritol with other organic nitrates. Mol Pharmacol 66:1372-1382
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1372-1382
-
-
Daiber, A.1
Oelze, M.2
Coldeway, M.3
Bachsmid, M.4
Wenzel, P.5
Sydow, K.6
-
37
-
-
11144354818
-
Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance
-
Sydow K, Daiber A, Oelze M, Chen Z, August M, Wendt M et al (2004) Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. J Clin Invest 113:482-489
-
(2004)
J Clin Invest
, vol.113
, pp. 482-489
-
-
Sydow, K.1
Daiber, A.2
Oelze, M.3
Chen, Z.4
August, M.5
Wendt, M.6
-
38
-
-
36448970474
-
Oxidative inhibition of mitochondrial aldehyde dehydrogenase promotes nitroglycerin tolerance in human blood vessels
-
Hink U, Daiber A, Kayhan N, Trischler J, Kattz C, Oelze M et al (2007) Oxidative inhibition of mitochondrial aldehyde dehydrogenase promotes nitroglycerin tolerance in human blood vessels. J Am Coll Cardiol 50:2226-2232
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 2226-2232
-
-
Hink, U.1
Daiber, A.2
Kayhan, N.3
Trischler, J.4
Kattz, C.5
Oelze, M.6
-
39
-
-
33749617767
-
Magnetic resonance angiography of the human meningeal artery: Implications for migraine
-
Schoonman GG, Bakker D, Schmitz N, van der Geest RJ, van der Grond J, Ferrari MD, van Buchem MA (2006) Magnetic resonance angiography of the human meningeal artery: Implications for migraine. J Magn Reson Imaging 24:918-921
-
(2006)
J Magn Reson Imaging
, vol.24
, pp. 918-921
-
-
Schoonman, G.G.1
Bakker, D.2
Schmitz, N.3
van der Geest, R.J.4
van der Grond, J.5
Ferrari, M.D.6
van Buchem, M.A.7
-
40
-
-
0037224354
-
Migraine can be induced by sildefanil without changes in middle cerebral artery diameter
-
Kruuse C, Thomsen LL, Birk S, Olesen J (2003) Migraine can be induced by sildefanil without changes in middle cerebral artery diameter. Brain 126:241-247
-
(2003)
Brain
, vol.126
, pp. 241-247
-
-
Kruuse, C.1
Thomsen, L.L.2
Birk, S.3
Olesen, J.4
|