Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model

Clinical Pharmacology and Therapeutics

Volumn 60, Issue 2, 1996, Pages 199-205

  Schmetterer, Leopold ^a   Wolzt, Michael ^a   Krejcy, Kurt ^a   Graselli, Ursula ^a   Findl, Oliver ^a   Eichler, Hans Georg ^a   Singer, Ernst A ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE; PLACEBO; SEROTONIN 1D RECEPTOR; SUMATRIPTAN; SUMATRIPTAN SUCCINATE;

ADULT; ARTICLE; BLOOD FLOW; BLOOD PRESSURE; BRAIN ARTERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; ELECTROCARDIOGRAM; HEADACHE; HEART RATE; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OPHTHALMIC ARTERY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; VASOCONSTRICTION; VASODILATATION;

EID: 0029977893     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(96)90136-8     Document Type: Article

References (29)

1. 1-like receptor agonist GR 453175. Cephalalgia 1989;9(suppl 9):23-33.
2. 1d receptor agonism predicts antimigraine efficacy. Headache 1991;31:228-31.
3. Sullivan JT, Prestone KL, Testa MP, Busch M, Jasinski DR. Psychoactivity and abuse potential of sumatriptan. Clin Pharmacol Ther 1992;52:635-42.
4. Ferrari MD, Melamed E, Gawel MJ, for the Subcutaneous Sumatriptan International Study Group. Treatment of migraine attacks with sumatriptan. N Engl J Med 1991;325:316-21.
5. Friberg L, Olesen J, Iversen HK, Sperling B. Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan. Lancet 1991;338:13-7.
6. Caekebeke JFV, Ferrari MD, Zwetsloot CP, Jansen J, Saxena PR. Antimigraine drug sumatriptan increases blood flow velocity in large cerebral arteries during migraine attacks. Neurology 1992;42:1522-6.
7. Buzzi MG, Carter WB, Shimizu T, Heath H, Moskowitz MA. Dihydroergotamine and sumatriptan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of trigeminal ganglion. Neuropharmacology 1991;30:1193-200.
8. Saxena PR. Is there still a case for the shunt hypothesis in migraine? In: Sandler M, Collins G, editors. Migraine: a spectrum of ideas. Oxford: Oxford Medical Publishers, 1990:191-7.
9. Iversen HK, Olesen J, Hansen PT. Intravenous nitro-glycerin as an experimental model of vascular headache: basic characteristics. Pain 1989;38:17-24.
10. Iversen HK, Olesen J. Experimental headache. In: Olesen J, Tfelt-Hansen P, Welch KMA, editors. The headache. New York: Raven Press, 1993.
11. Gee W, Rhodes M, Denstman FJ, Jaeger RM, Tilly DA, Stephens HW, et al. Ocular pneumoplethysmography in head-injured patients. J Neurosurg 1983;59: 46-50.
12. Gee W. Ocular pneumoplethysmography. Surv Ophthalmol 1985;29:276-92.
13. Aaslid R, Markwalder TM, Nornes H. Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 1982;57: 769-74.
14. Lieb WE, Cohen SM, Merton DA, Shields JA, Mitchell DG, Goldberg BB. Color Doppler imaging of the eye and the orbit. Arch Ophthalmol 1991;109:527-31.
15. Schmetterer L, Lexer F, Unfried C, Sattmann H, Percher A. Topical measurement of fundus pulsations. Optical Engineering 1995;34:711-6.
16. Wolzt M, Schmetterer L, Rheinberger A, Salomon A, Unfried C, Breiteneder H, et al. Comparison of noninvasive methods for the assessment of hemodynamic drug effects in healthy male and female volunteers. Br J Clin Pharmacol 1995;39:347-59.
17. Schmetterer L, Kemmler D, Breiteneder H, Alschinger C, Koppensteiner R, Lexer F, et al. A randomized, placebo-controlled, double blind crossover study of the effect of pentoxifylline on ocular fundus pulsations. Am J Ophthalmol 1996;121:169-76.
18. Langham ME, Farrell RA, O'Brien V, Silver DM, Schilder P. Blood flow in the human eye. Acta Ophthalmol 1989;67(suppl 191):9-13.
19. Humphrey PPA, Goadsby PJ. The mode of action of sumatriptan is vascular? A debate. Cephalalgia 1994; 14:401-10.
20. Goadsby PJ, Edvinsson L, Ekman R. Vasoactive peptide release in the extracerebral circulation of humans during acute cluster headache. Ann Neurol 1990;28: 183-7.
21. Nicolodi M, Del Bianco E. Sensory neuropeptides (substance P, calcitonin gene-related peptide) and vasoactive intestinal polypeptide in human saliva: their pattern in migraine and cluster headache. Cephalalgia 1990;10:39-50.
22. Thomsen LL, Iversen HK, Brinck TA, Olesen J. Arterial supersensitivity to nitric oxide (nitroglycerin) in migraine sufferers. Cephalalgia 1993;13:395-9.
23. Fanciullacci M, Alessandri M, Figini M, Geppetti P, Michelacci S. Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack. Pain 1995;60:119-23.
24. 1-like receptors in the reduction of porcine cranial arteriovenous anastomotic shunting by sumatriptan. Br J Pharmacol 1991;102:323-30.
25. Goadsby PJ, Edvinsson L. The trigeminovascular system and migraine: studies characterizing cerebrovascular and neuropeptide changes seen in man and cat. Ann Neurol 1993;33:48-56.
26. Vincent MB, White LR, Bakken IJ, Sjaastad O. Sumatriptan relaxes isolated porcine ophthalmic artery, but inhibits VIP-induced relaxation. Cephalalgia 1993;13:378-82.
27. Aim A, Bill A. Ocular circulation. In: Moses RA, Hart WM, editors. Adlers physiology of the eye. St Louis: Mosby, 1987:183-203.
28. 1-agonist, on the systemic, pulmonary, and coronary circulation. Circulation 1993;87:401-5.
29. Scott AK, Grimes S, Critchley M, Breckenridge AM, Thomson C, Pilgrim AJ. Sumatriptan and cerebral perfusion in healthy volunteers. Br J Clin Pharmacol 1992;33:401-4.