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Volumn 98, Issue 2, 2008, Pages 117-123

Elevated p21 expression is associated with poor prognosis of rectal stromal tumors after resection

Author keywords

Gists; P21; P53; PCNA; Prognosis; Rectum

Indexed keywords

CYCLINE; KI 67 ANTIGEN; PROTEIN P21; PROTEIN P53; STEM CELL FACTOR RECEPTOR;

EID: 49149109883     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21094     Document Type: Article
Times cited : (16)

References (39)
  • 1
    • 0031904592 scopus 로고    scopus 로고
    • Immunophenotype, proliferation, DNA ploidy, and biological behavior of gastrointestinal stromal tumors: A multivariate clinicopathologic study
    • Rudolph P, Gloeckner K, Parwaresch R, et al.: Immunophenotype, proliferation, DNA ploidy, and biological behavior of gastrointestinal stromal tumors: A multivariate clinicopathologic study. Hum Pathol 1998;29:791-800.
    • (1998) Hum Pathol , vol.29 , pp. 791-800
    • Rudolph, P.1    Gloeckner, K.2    Parwaresch, R.3
  • 2
    • 11244356587 scopus 로고    scopus 로고
    • Evaluation of prognosis for malignant rectal gastrointestinal stromal tumor by clinical parameters and immunohistochemical staining
    • Changchien CR, Wu MC, Tasi WS, et al.: Evaluation of prognosis for malignant rectal gastrointestinal stromal tumor by clinical parameters and immunohistochemical staining. Dis Colon Rectum 2004;47:1922-1929.
    • (2004) Dis Colon Rectum , vol.47 , pp. 1922-1929
    • Changchien, C.R.1    Wu, M.C.2    Tasi, W.S.3
  • 3
    • 33646543703 scopus 로고    scopus 로고
    • Clinical, pathologic, and immunohistochemical characteristics of gastrointestinal stromal tumors of the colon and rectum: Implications for surgical management and adjuvant therapies
    • Hassan I, You YN, Dozois EJ, et al.: Clinical, pathologic, and immunohistochemical characteristics of gastrointestinal stromal tumors of the colon and rectum: Implications for surgical management and adjuvant therapies. Dis Colon Rectum 2006;49:609-615.
    • (2006) Dis Colon Rectum , vol.49 , pp. 609-615
    • Hassan, I.1    You, Y.N.2    Dozois, E.J.3
  • 4
    • 0033984319 scopus 로고    scopus 로고
    • Two hundred gastrointestinal stromal tumors: Recurrence patterns and prognostic factors for survival
    • DeMatteo RP, Lewis JJ, Leung D, et al.: Two hundred gastrointestinal stromal tumors: Recurrence patterns and prognostic factors for survival. Ann Surg 2000;231:51-58.
    • (2000) Ann Surg , vol.231 , pp. 51-58
    • DeMatteo, R.P.1    Lewis, J.J.2    Leung, D.3
  • 5
    • 10744225271 scopus 로고    scopus 로고
    • Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors
    • Antonescu CR, Sommer G, Sarran L, et al.: Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors. Clin Cancer Res 2003;9:3329-3337.
    • (2003) Clin Cancer Res , vol.9 , pp. 3329-3337
    • Antonescu, C.R.1    Sommer, G.2    Sarran, L.3
  • 6
    • 11144284051 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up
    • Miettinen M, Sobin LH, Lasota J: Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol 2005;29:52-68.
    • (2005) Am J Surg Pathol , vol.29 , pp. 52-68
    • Miettinen, M.1    Sobin, L.H.2    Lasota, J.3
  • 7
    • 1342330832 scopus 로고    scopus 로고
    • Immunohistochemical analyses of gastric stromal tumors in Taiwanese
    • Hu TH, Lin JW, Changchien CS, et al.: Immunohistochemical analyses of gastric stromal tumors in Taiwanese. J Formos Med Assoc 2003;102:707-714.
    • (2003) J Formos Med Assoc , vol.102 , pp. 707-714
    • Hu, T.H.1    Lin, J.W.2    Changchien, C.S.3
  • 8
    • 0036301722 scopus 로고    scopus 로고
    • Diagnosis of gastrointestinal stromal tumors: A consensus approach
    • Fletcher CD, Berman JJ, Corless C, et al.: Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002;33:459-465.
    • (2002) Hum Pathol , vol.33 , pp. 459-465
    • Fletcher, C.D.1    Berman, J.J.2    Corless, C.3
  • 9
    • 0026556971 scopus 로고
    • A clinicopathologic and immunohistochemical study of gastrointestinal stromal tumors
    • Ueyama T, Guo KJ, Hashimoto H, et al.: A clinicopathologic and immunohistochemical study of gastrointestinal stromal tumors. Cancer 1992;69:947-955.
    • (1992) Cancer , vol.69 , pp. 947-955
    • Ueyama, T.1    Guo, K.J.2    Hashimoto, H.3
  • 10
    • 33644931885 scopus 로고    scopus 로고
    • Expression and prognostic role of molecular markers in 99 KIT-positive gastric stromal tumors in Taiwanese
    • Hu TH, Chuah SK, Lin JW, et al.: Expression and prognostic role of molecular markers in 99 KIT-positive gastric stromal tumors in Taiwanese. World J Gastroenterol 2006;12:595-602.
    • (2006) World J Gastroenterol , vol.12 , pp. 595-602
    • Hu, T.H.1    Chuah, S.K.2    Lin, J.W.3
  • 11
    • 0026775085 scopus 로고
    • Muscle differentiation and clinicopathologic features of gastrointestinal stromal tumors
    • Franquemont DW, Frierson HF Jr: Muscle differentiation and clinicopathologic features of gastrointestinal stromal tumors. Am J Surg Pathol 1992;16:947-954.
    • (1992) Am J Surg Pathol , vol.16 , pp. 947-954
    • Franquemont, D.W.1    Frierson Jr, H.F.2
  • 12
    • 0036308006 scopus 로고    scopus 로고
    • Clinicopathologic correlations in gastrointestinal stromal tumors
    • Fletcher CD: Clinicopathologic correlations in gastrointestinal stromal tumors. Hum Pathol 2002;33:455.
    • (2002) Hum Pathol , vol.33 , pp. 455
    • Fletcher, C.D.1
  • 13
    • 0031015032 scopus 로고    scopus 로고
    • Prognostic significance of DNA ploidy and proliferative index (MIB-1 index) in gastrointestinal stromal tumors
    • Carrillo R, Candia A, Rodriguez-Peralto JL, et al.: Prognostic significance of DNA ploidy and proliferative index (MIB-1 index) in gastrointestinal stromal tumors. Hum Pathol 1997;28:160-165.
    • (1997) Hum Pathol , vol.28 , pp. 160-165
    • Carrillo, R.1    Candia, A.2    Rodriguez-Peralto, J.L.3
  • 14
    • 10744233692 scopus 로고    scopus 로고
    • Prognostic indicators for gastrointestinal stromal tumours: A clinicopathological and immunohistochemical study of 108 resected cases of the stomach
    • Wong NA, Young R, Malcomson RD, et al.: Prognostic indicators for gastrointestinal stromal tumours: A clinicopathological and immunohistochemical study of 108 resected cases of the stomach. Histopathology 2003;43:118-126.
    • (2003) Histopathology , vol.43 , pp. 118-126
    • Wong, N.A.1    Young, R.2    Malcomson, R.D.3
  • 15
    • 0028795581 scopus 로고
    • Differentiation and risk assessment of gastrointestinal stromal tumors
    • Franquemont DW: Differentiation and risk assessment of gastrointestinal stromal tumors. Am J Clin Pathol 1995;103:41-47.
    • (1995) Am J Clin Pathol , vol.103 , pp. 41-47
    • Franquemont, D.W.1
  • 16
    • 33745469852 scopus 로고    scopus 로고
    • Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications
    • Sabah M, Cummins R, Leader M, et al.: Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications. Hum Pathol 2006;37:648-655.
    • (2006) Hum Pathol , vol.37 , pp. 648-655
    • Sabah, M.1    Cummins, R.2    Leader, M.3
  • 17
    • 0032556952 scopus 로고    scopus 로고
    • p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
    • Cayrol C, Knibiehler M, Ducommun B: p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells. Oncogene 1998;16:311-320.
    • (1998) Oncogene , vol.16 , pp. 311-320
    • Cayrol, C.1    Knibiehler, M.2    Ducommun, B.3
  • 18
    • 0029103598 scopus 로고
    • p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
    • Macleod KF, Sherry N, Hannon G, et al.: p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 1995;9:935-944.
    • (1995) Genes Dev , vol.9 , pp. 935-944
    • Macleod, K.F.1    Sherry, N.2    Hannon, G.3
  • 19
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry WS, Tokino T, Velculescu VE, et al.: WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • el-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 20
    • 0028986639 scopus 로고
    • p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells
    • Parker SB, Eichele G, Zhang P, et al.: p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 1995;267:1024-1027.
    • (1995) Science , vol.267 , pp. 1024-1027
    • Parker, S.B.1    Eichele, G.2    Zhang, P.3
  • 21
    • 33750618580 scopus 로고    scopus 로고
    • Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: Relevance of cellularity and p27kip1
    • Nemoto Y, Mikami T, Hana K, et al.: Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: Relevance of cellularity and p27kip1. Pathol Int 2006;56:724-731.
    • (2006) Pathol Int , vol.56 , pp. 724-731
    • Nemoto, Y.1    Mikami, T.2    Hana, K.3
  • 22
    • 0032955439 scopus 로고    scopus 로고
    • Prognosis of gastrointestinal smooth-muscle (stromal) tumors: Dependence on anatomic site
    • Emory TS, Sobin LH, Lukes L, et al.: Prognosis of gastrointestinal smooth-muscle (stromal) tumors: Dependence on anatomic site. Am J Surg Pathol 1999;23:82-87.
    • (1999) Am J Surg Pathol , vol.23 , pp. 82-87
    • Emory, T.S.1    Sobin, L.H.2    Lukes, L.3
  • 23
    • 14844314779 scopus 로고    scopus 로고
    • The expression of p53 and bcl-2 in gastrointestinal stromal tumours is associated with anatomical site, and p53 expression is associated with grade and clinical outcome
    • Feakins RM: The expression of p53 and bcl-2 in gastrointestinal stromal tumours is associated with anatomical site, and p53 expression is associated with grade and clinical outcome. Histopathology 2005;46:270-279.
    • (2005) Histopathology , vol.46 , pp. 270-279
    • Feakins, R.M.1
  • 24
    • 0023091627 scopus 로고
    • Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta
    • Bravo R, Frank R, Blundell PA, et al.: Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature 1987;326:515-517.
    • (1987) Nature , vol.326 , pp. 515-517
    • Bravo, R.1    Frank, R.2    Blundell, P.A.3
  • 25
    • 0031594705 scopus 로고    scopus 로고
    • Nuclear accumulation of p21Cip1 at the onset of mitosis: A role at the G2/M-phase transition
    • Dulic V, Stein GH, Far DF, et al.: Nuclear accumulation of p21Cip1 at the onset of mitosis: A role at the G2/M-phase transition. Mol Cell Biol 1998;18:546-557.
    • (1998) Mol Cell Biol , vol.18 , pp. 546-557
    • Dulic, V.1    Stein, G.H.2    Far, D.F.3
  • 26
    • 0031055839 scopus 로고    scopus 로고
    • Reduced p21(WAF1/CIP1) expression and p53 mutation in hepatocellular carcinomas
    • Hui AM, Kanai Y, Sakamoto M, et al.: Reduced p21(WAF1/CIP1) expression and p53 mutation in hepatocellular carcinomas. Hepatology 1997;25:575-579.
    • (1997) Hepatology , vol.25 , pp. 575-579
    • Hui, A.M.1    Kanai, Y.2    Sakamoto, M.3
  • 27
    • 0034077411 scopus 로고    scopus 로고
    • Reduced p21(WAF1/CIP1) protein expression is predominantly related to altered p53 in hepatocellular carcinomas
    • Shi YZ, Hui AM, Takayama T, et al.: Reduced p21(WAF1/CIP1) protein expression is predominantly related to altered p53 in hepatocellular carcinomas. Br J Cancer 2000;83:50-55.
    • (2000) Br J Cancer , vol.83 , pp. 50-55
    • Shi, Y.Z.1    Hui, A.M.2    Takayama, T.3
  • 28
    • 0033624177 scopus 로고    scopus 로고
    • Loss of p21Waf1 expression is a strong predictor of reduced survival in primary superficial bladder cancers
    • Migaldi M, Sgambato A, Garagnani L, et al.: Loss of p21Waf1 expression is a strong predictor of reduced survival in primary superficial bladder cancers. Clin Cancer Res 2000;6:3131-3138.
    • (2000) Clin Cancer Res , vol.6 , pp. 3131-3138
    • Migaldi, M.1    Sgambato, A.2    Garagnani, L.3
  • 29
    • 0032516238 scopus 로고    scopus 로고
    • Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1
    • Halaban R, Cheng E, Zhang Y, et al.: Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1. Oncogene 1998;16:2489-2501.
    • (1998) Oncogene , vol.16 , pp. 2489-2501
    • Halaban, R.1    Cheng, E.2    Zhang, Y.3
  • 30
    • 0028236846 scopus 로고
    • Induction of WAF1/CIP1 by a p53-independent pathway
    • Michieli P, Chedid M, Lin D, et al.: Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res 1994;54:3391-3395.
    • (1994) Cancer Res , vol.54 , pp. 3391-3395
    • Michieli, P.1    Chedid, M.2    Lin, D.3
  • 31
    • 0031593570 scopus 로고    scopus 로고
    • Expression of p21WAF1/CIP1 in soft tissue sarcomas: A comparative immunohistochemical study with p53 and Ki-67
    • Pindzola JA, Palazzo JP, Kovatich AJ, et al.: Expression of p21WAF1/CIP1 in soft tissue sarcomas: A comparative immunohistochemical study with p53 and Ki-67. Pathol Res Pract 1998;194:685-691.
    • (1998) Pathol Res Pract , vol.194 , pp. 685-691
    • Pindzola, J.A.1    Palazzo, J.P.2    Kovatich, A.J.3
  • 32
    • 33748596056 scopus 로고    scopus 로고
    • Clinicopathological and immunohistochemical analysis of gastrointestinal stromal tumor
    • Liu FY, Qi JP, Xu FL, et al.: Clinicopathological and immunohistochemical analysis of gastrointestinal stromal tumor. World J Gastroenterol 2006;12:4161-4165.
    • (2006) World J Gastroenterol , vol.12 , pp. 4161-4165
    • Liu, F.Y.1    Qi, J.P.2    Xu, F.L.3
  • 33
    • 0000389767 scopus 로고    scopus 로고
    • p21/WAF1, p53 and PCNA expression and p53 mutation status in hepatocellular carcinoma
    • Qin LF, Ng IO, Fan ST, et al.: p21/WAF1, p53 and PCNA expression and p53 mutation status in hepatocellular carcinoma. Int J Cancer 1998;79:424-428.
    • (1998) Int J Cancer , vol.79 , pp. 424-428
    • Qin, L.F.1    Ng, I.O.2    Fan, S.T.3
  • 34
    • 0035935259 scopus 로고    scopus 로고
    • Exogenous expression of p21(WAF1/CIP1) exerts cell growth inhibition and enhances sensitivity to cisplatin in hepatoma cells
    • Qin LF, Ng IO: Exogenous expression of p21(WAF1/CIP1) exerts cell growth inhibition and enhances sensitivity to cisplatin in hepatoma cells. Cancer Lett 2001;172:7-15.
    • (2001) Cancer Lett , vol.172 , pp. 7-15
    • Qin, L.F.1    Ng, I.O.2
  • 35
    • 0028271583 scopus 로고
    • Prognostic significance of proliferating cell nuclear antigen expression in hepatocellular carcinoma
    • Ng IO, Lai EC, Fan ST, et al.: Prognostic significance of proliferating cell nuclear antigen expression in hepatocellular carcinoma. Cancer 1994;73:2268-2274.
    • (1994) Cancer , vol.73 , pp. 2268-2274
    • Ng, I.O.1    Lai, E.C.2    Fan, S.T.3
  • 36
    • 0028845577 scopus 로고
    • Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer
    • Gao X, Chen YQ, Wu N, et al.: Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer. Oncogene 1995;11:1395-1398.
    • (1995) Oncogene , vol.11 , pp. 1395-1398
    • Gao, X.1    Chen, Y.Q.2    Wu, N.3
  • 37
    • 0036771793 scopus 로고    scopus 로고
    • Elevated (> or =10%) MIB-1 proliferative index correlates with poor outcome in gastric stromal tumor patients: A study of 35 cases
    • Toquet C, Le Neel JC, Guillou L, et al: Elevated (> or =10%) MIB-1 proliferative index correlates with poor outcome in gastric stromal tumor patients: A study of 35 cases. Dig Dis Sci 2002;47:2247-2253.
    • (2002) Dig Dis Sci , vol.47 , pp. 2247-2253
    • Toquet, C.1    Le Neel, J.C.2    Guillou, L.3
  • 38
    • 0034049784 scopus 로고    scopus 로고
    • Predicting metastatic risk of gastrointestinal stromal tumors: Role of cell proliferation and cell cycle regulatory proteins
    • Panizo-Santos A, Sola I, Vega F, et al.: Predicting metastatic risk of gastrointestinal stromal tumors: Role of cell proliferation and cell cycle regulatory proteins. Int J Surg Pathol 2000;8:133-144.
    • (2000) Int J Surg Pathol , vol.8 , pp. 133-144
    • Panizo-Santos, A.1    Sola, I.2    Vega, F.3
  • 39
    • 0031847132 scopus 로고    scopus 로고
    • Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces, and gastrointestinal tract
    • Suster S, Fisher C, Moran CA: Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces, and gastrointestinal tract. Am J Surg Pathol 1998;22:863-872.
    • (1998) Am J Surg Pathol , vol.22 , pp. 863-872
    • Suster, S.1    Fisher, C.2    Moran, C.A.3


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