Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 16, 2008, Pages 7691-7697

  Ansari, Farzana Latif ^a   Iftikhar, Fatima ^a   Ihsan ul Haq, ^a   Mirza, Bushra ^a   Baseer, Mohammad ^a   Rashid, Umer ^a  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

1,5 Benzothiazepines; Antibacterial; Cholinesterase inhibitors; Potato disk tumor inhibitors; Solid phase synthesis

Indexed keywords

2 (2'' CHLOROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (2'' FLUOROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (2'' METHOXYPHENYL) 4 (3'HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (3'' FLUOROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (3'' HYDROXYPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (3'' METHOXYPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZAOTHIAZEPINE; 2 (3'',4'' DIMETHOXYPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZO THIAZEPINE; 2 (4'' BROMOPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' CHLOROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' FLUOROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' HYDROXY 3'' METHOXYPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' HYDROXYPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' METHOXYPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' METHYLPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' N,N DIMETHYLAMINO) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (4'' NITROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (5'' METHYLTHIEN 2'' YL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (PHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (PYRIDIN 3'' YL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO-1,5 BENZOTHIAZEPINE; 2 (PYRIDIN 4'' YL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (PYRIDIN2'' YL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2 (THIEN 2'' YL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2(3'' CHLOROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2(3'' NITROPHENYL) 4 (3' HYDROXYPHENYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE; 2,3 DIHYDRO 1,5 BENZOTHIAZEPINE DERIVATIVE; 3' HYDROXY 2,3 DIHYDROBENZOTHIAZEPINE DERIVATIVE; BENZOTHIAZEPINE DERIVATIVE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHOLINESTERASE INHIBITION; SOLID PHASE SYNTHESIS;

ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASES; COMBINATORIAL CHEMISTRY TECHNIQUES; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; PLANT TUMORS; THIAZEPINES;

SOLANUM TUBEROSUM;

EID: 49149108879     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.07.009     Document Type: Article

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