Three-dimensional microstructure of the bone in a hamster model of senile osteoporosis

Bone

Volumn 43, Issue 3, 2008, Pages 494-500

  Chen, Huayue ^a   Zhou, Xiangrong ^a   Washimi, Yuki ^b   Shoumura, Shizuko ^c  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

^c CHUBU GAKUIN UNIVERSITY   (Japan)

Author keywords

Aging; Bone structure; Hamster; Micro CT; Three dimensional microstructure

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE MASS; BONE STRUCTURE; CONTROLLED STUDY; CORTICAL BONE; DIAPHYSIS; FEMALE; FEMUR; HAMSTER; MALE; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOLYSIS; SENILE OSTEOPOROSIS; SEX DIFFERENCE; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING; TIBIA; TRABECULAR BONE; VERTEBRA BODY;

ANIMALS; BIOMECHANICS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; CRICETINAE; FEMALE; HUMANS; MALE; MESOCRICETUS; OSTEOPOROSIS; SEX FACTORS; TIBIA; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 49149103625     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.05.004     Document Type: Article

References (45)

1. National Institutes of Health. Osteoporosis prevention, diagnosis, and therapy. NIH Consens Statement 17 (2000) 1-45
2. Parfitt A.M. Age-related structural changes in trabecular and cortical bone: cellular mechanisms and biomechanical consequences. Calcif Tissue Int 36 Suppl 1 (1984) S123-S128
3. Riggs B.L., Khosla S., and Melton III L.J. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 13 (1998) 763-773
4. Klein R.F., Mitchell S.R., Phillips T.J., Belknap J.K., and Orwoll E.S. Quantitative trait loci affecting peak bone mineral density in mice. J Bone Miner Res. 13 (1998) 1648-1656
5. Ioannidis J.P., Ng M.Y., Sham P.C., Zintzaras E., Lewis C.M., Deng H.W., et al. Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass. J Bone Miner Res. 22 (2007) 173-183
6. Halloran B.P., Ferguson V.L., Simske S.J., Burghardt A., Venton L.L., and Majumdar S. Changes in bone structure and mass with advancing age in the male C57BL/6J mouse. J Bone Miner Res 17 (2002) 1044-1050
7. Ferguson V.L., Ayers R.A., Bateman T.A., and Simske S.J. Bone development and age-related bone loss in male C57BL/6J mice. Bone 33 (2003) 387-398
8. Li X.J., Jee W.S., Ke H.Z., Mori S., and Akamine T. Age-related changes of cancellous and cortical bone histomorphometry in female Sprague-Dawley rats. Cells Mater Suppl 1 (1991) 25-35
9. Wang L., Banu J., McMahan C.A., and Kalu D.N. Male rodent model of age-related bone loss in men. Bone 29 (2001) 141-148
10. Pietschmann P., Skalicky M., Kneissel M., Rauner M., Hofbauer G., Stupphann D., et al. Bone structure and metabolism in a rodent model of male senile osteoporosis. Exp Gerontol 42 (2007) 1099-1108
11. Shea J.E., Miller S.C., Poole D.C., and Mattson J.P. Cortical bone dynamics, strength, and densitometry after induction of emphysema in hamsters. J Appl Physiol 95 (2003) 631-634
12. Rousseau K., Atcha Z., Denton J., Cagampang F.R., Ennos A.R., Freemont A.J., et al. Skeletal bone morphology is resistant to the high amplitude seasonal leptin cycle in the Siberian hamster. J Endocrinol 186 (2005) 475-479
13. Kalu D.N. The ovariectomized rat model of postmenopausal bone loss. Bone Miner 15 (1991) 175-191
14. Riggs B.L. Overview of osteoporosis. West J Med 154 (1991) 63-77
15. Väänänen H.K. Pathogenesis of osteoporosis. Calcif Tissue Int 49 Suppl (1991) S11-S14
16. Mosekilde L. Sex differences in age-related loss of vertebral trabecular bone mass and structure-biomechanical consequences. Bone 10 (1989) 425-432
17. Ding M., and Hvid I. Quantification of age-related changes in the structure model type and trabecular thickness of human tibial cancellous bone. Bone 26 (2000) 291-295
18. Chen H, Shoumura S, Emura S, Bunai Y. Regional variations of vertebral trabecular bone microstructure with age and gender. Osteoporos Int (in press).
19. Khosla S., Melton III L.J., and Riggs B.L. Osteoporosis: gender differences and similarities. Lupus 8 (1999) 393-399
20. Sigurdsson G., Aspelund T., Chang M., Jonsdottir B., Sigurdsson S., Eiriksdottir G., et al. Increasing sex difference in bone strength in old age: the Age, Gene/Environment Susceptibility-Reykjavik study (AGES-REYKJAVIK). Bone 39 (2006) 644-651
21. Eckstein F., Matsuura M., Kuhn V., Priemel M., Müller R., Link T.M., et al. Sex differences of human trabecular bone microstructure in aging are site-dependent. J Bone Miner Res 22 (2007) 817-824
22. Bar-Shira-Maymon B., Coleman R., Cohen A., Steinhagen-Thiessen E., and Silbermann M. Age-related bone loss in lumbar vertebrae of CW-1 female mice: a histomorphometric study. Calcif Tissue Int 44 (1989) 36-45
23. Weiss A., Arbell I., Steirhagen-Thiessen E., and Silbermann M. Structural changes in aging bone: osteopenia in the proximal femurs of female mice. Bone 12 (1991) 165-172
24. Chen H., Shoumura S., and Emura S. Ultrastructural changes in bones of the senescence-accelerated mouse (SAMP6): a murine model for senile osteoporosis. Histol Histopathol 19 (2004) 677-685
25. Silva M.J., Brodt M.D., Ko M., and Abu-Amer Y. Impaired marrow osteogenesis is associated with reduced endocortical bone formation but does not impair periosteal bone formation in long bones of SAMP6 mice. J Bone Miner Res 20 (2005) 419-427
26. Wronski T.J., Dann L.M., Scott K.S., and Cintrón M. Long-term effects of ovariectomy and aging on the rat skeleton. Calcif Tissue Int 45 (1989) 360-366
27. Erben R.G., Eberle J., Stahr K., and Goldberg M. Androgen deficiency induces high turnover osteopenia in aged male rats: a sequential histomorphometric study. J Bone Miner Res 15 (2000) 1085-1098
28. Wronski T.J., Dann L.M., and Horner S.L. Time course of vertebral osteopenia in ovariectomized rats. Bone 10 (1989) 295-301
29. Hendry III W.J., Sheehan D.M., Khan S.A., and May J.V. Developing a laboratory animal model for perinatal endocrine disruption: the hamster chronicles. Exp Biol Med 227 (2002) 709-723
30. Kasim-Karakas S.E., Vriend H., Almario R., Chow L.C., and Goodman M.N. Effects of dietary carbohydrates on glucose and lipid metabolism in golden Syrian hamsters. J Lab Clin Med 128 (1996) 208-213
31. Hikiji H., Takato T., Shimizu T., and Ishii S. The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease. Prog Lipid Res 47 (2008) 107-126
32. Odgaard A., and Gundersen H.J. Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions. Bone 14 (1993) 173-182
33. Lorensen W.E., and Cline H.E. Marching cubes: a high resolution 3D surface construction algorithm. Comput Graph 21 (1987) 163-169
34. Hildebrand T., and Rüegsegger P. A new method for the model-independent assessment of thickness in three-dimensional images. J Microsc 185 (1997) 67-75
35. Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2 (1987) 595-610
36. Hildebrand T., and Rüegsegger P. Quantification of bone microarchitecture with the structure model index. Comput Methods Biomech Biomed Engin 1 (1997) 15-23
37. Harrigan T.P., and Mann R.W. Characterization of microstructural anisotropy in orthotropic materials using a second rank tensor. J Mater Sci 19 (1984) 761-767
38. Hahn M., Vogel M., Pompesius-Kempa M., and Delling G. Trabecular bone pattern factor -a new parameter for simple quantification of bone microarchitecture. Bone 13 (1992) 327-330
39. Bagi C.M., Hanson N., Andresen C., Pero R., Lariviere R., Turner C.H., et al. The use of micro-CT to evaluate cortical bone geometry and strength in nude rats: correlation with mechanical testing, pQCT and DXA. Bone 38 (2006) 136-144
40. Fukuda S., and Iida H. Age-related changes in bone mineral density, cross-sectional area and the strength of long bones in the hind limbs and first lumbar vertebra in female Wistar rats. J Vet Med Sci 66 (2004) 755-760
41. Iida H., and Fukuda S. Age-related changes in bone mineral density, cross-sectional area and strength at different skeletal sites in male rats. J Vet Med Sci 64 (2002) 29-34
42. Judex S., Garman R., Squire M., Busa B., Donahue L.R., and Rubin C. Genetically linked site-specificity of disuse osteoporosis. J Bone Miner Res. 19 (2004) 607-613
43. Kobayashi Y., Goto S., Tanno T., Yamazaki M., and Moriya H. Regional variations in the progression of bone loss in two different mouse osteopenia models. Calcif Tissue Int 62 (1998) 426-436
44. Thomsen J.S., Ebbesen E.N., and Mosekilde L.I. Age-related differences between thinning of horizontal and vertical trabeculae in human lumbar bone as assessed by a new computerized method. Bone 31 (2002) 136-142
45. Akkus O., Adar F., and Schaffler M.B. Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone. Bone 34 (2004) 443-453