In vitro differentiation of reprogrammed murine somatic cells into hepatic precursor cells

Biological Chemistry

Volumn 389, Issue 7, 2008, Pages 889-896

  Cantz, Tobias ^a,b   Bleidißel, Martina ^a   Stehling, Martin ^a   Schöler, Hans R ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Embryonic stem cells; Endodermal differentiation; Fusion; Metabolic liver disorders; Reprogramming

Indexed keywords

GREEN FLUORESCENT PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; EMBRYO; EMBRYONIC STEM CELL; ENDODERM; ENGRAFTMENT; FLUORESCENCE ACTIVATED CELL SORTING; IN VITRO STUDY; LIVER CELL; LIVER DISEASE; LIVER TRANSPLANTATION; MONONUCLEAR CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PLURIPOTENT STEM CELL; POLYPLOIDY; PRIORITY JOURNAL; SOMATIC CELL THERAPY; TERATOMA; TOXIC MILK MICE; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL FUSION; CELL TRANSPLANTATION; DISEASE MODELS, ANIMAL; ENDODERM; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HEPATOCYTES; MICE; NUCLEAR REPROGRAMMING; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; STEM CELLS; TRANSGENES;

MURINAE; MUS;

EID: 49149089216     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2008.107     Document Type: Article

References (37)

1. Ala, A. and Schilsky, M.L. (2004). Wilson disease: pathophysiology, diagnosis, treatment, and screening. Clin. Liver Dis. 8, 787-805.
2. Boiani, M., Eckardt, S., Schöler, H.R., and McLaughlin, K.J. (2002). Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev. 16, 1209-1219.
3. Chinzei, R., Tanaka, Y., Shimizu-Saito, K., Hara, Y., Kakinuma, S., Watanabe, M., Teramoto, K., Arii, S., Takase, K., Sato, C., et al. (2002). Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes. Hepatology 36, 22-29.
4. Choi, D., Oh, H.J., Chang, U.J., Koo, S.K., Jiang, J.X., Hwang, S.Y., Lee, J.D., Yeoh, G.C., Shin, H.S., Lee, J.S., and Oh, B. (2002). In vivo differentiation of mouse embryonic stem cells into hepatocytes. Cell Transplant. 11, 359-368.
5. Collas, P. and Robl, J.M. (1991). Relationship between nuclear remodeling and development in nuclear transplant rabbit embryos. Biol. Reprod. 45, 455-465.
6. Coronado, V., Nanji, M., and Cox, D.W. (2001). The Jackson toxic milk mouse as a model for copper loading. Mamm. Genome 12, 793-795.
7. Cowan, C.A., Atienza, J., Melton, D.A., and Eggan, K. (2005). Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369-1373.
8. Do, J.T. and Schöler, H.R. (2004). Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells 22, 941-949.
9. Do, J.T. and Schöler, H.R. (2005). Comparison of neurosphere cells with cumulus cells after fusion with embryonic stem cells: reprogramming potential. Reprod. Fertil. Dev. 17, 143-149.
10. Fausto, N. (2004). Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology 39, 1477-1487.
11. Gouon-Evans, V., Boussemart, L., Gadue, P., Nierhoff, D., Koehler, C.I., Kubo, A., Shafritz, D.A., and Keller, G. (2006). BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat. Biotechnol. 24, 1402-1411.
12. Hamazaki, T., Iiboshi, Y., Oka, M., Papst, P.J., Meacham, A.M., Zon, L.I., and Terada, N. (2001). Hepatic maturation in differentiating embryonic stem cells in vitro. FEBS Lett. 497, 15-19.
13. Heo, J., Factor, V.M., Uren, T., Takahama, Y., Lee, J.S., Major, M., Feinstone, S.M., and Thorgeirsson, S.S. (2006). Hepatic precursors derived from murine embryonic stem cells contribute to regeneration of injured liver. Hepatology 44, 1478-1486.
14. Ishizaka, S., Shiroi, A., Kanda, S., Yoshikawa, M., Tsujinoue, H., Kuriyama, S., Hasuma, T., Nakatani, K., and Takahashi, K. (2002). Development of hepatocytes from ES cells after transfection with the HNF-3b gene. FASEB J. 16, 1444-1446.
15. Jochheim, A., Cieslak, A., Hillemann, T., Cantz, T., Scharf, J., Manns, M.P., and Ott, M. (2003). Multi-stage analysis of differential gene expression in BALB/C mouse liver development by high-density microarrays. Differentiation 71, 62-72.
16. Jones, E.A., Tosh, D., Wilson, D.I., Lindsay, S., and Forrester, L.M. (2002). Hepatic differentiation of murine embryonic stem cells. Exp. Cell Res. 272, 15-22.
17. Kania, G., Blyszczuk, P., Jochheim, A., Ott, M., and Wobus, A.M. (2004). Generation of glycogen- and albumin-producing hepatocyte-like cells from embryonic stem cells. Biol. Chem. 385, 943-953.
18. Kumashiro, Y., Asahina, K., Ozeki, R., Shimizu-Saito, K., Tanaka, Y., Kida, Y., Inoue, K., Kaneko, M., Sato, T., Teramoto, K., et al. (2005). Enrichment of hepatocytes differentiated from mouse embryonic stem cells as a transplantable source. Transplantation 79, 550-557.
19. Maherali, N., Sridhara, R., Wei, X., Utikal, J., Eminli, S., Arnold, K., Stadtfeld, M., Yachechko, R., Tchieu, J., Jaenisch, R., et al. (2007). Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55-70.
20. Matsumura, H., Tada, M., Otsuji, T., Yasuchika, K., Nakatsuji, N., Surani, A., and Tada, T. (2007). Targeted chromosome elimination from ES-somatic hybrid cells. Nat. Methods 4, 23-25.
21. Matveeva, N.M., Shilov, A.G., Kaftanovskaya, E.M., Maximovsky, L.P., Zhelezova, A.I., Golubitsa, A.N., Bayborodin, S.I., Fokina, M.M., and Serov, O.L. (1998). In vitro and in vivo study of pluripotency in intraspecific hybrid cells obtained by fusion of murine embryonic stem cells with splenocytes. Mol. Reprod. Dev. 50, 128-138.
22. Miyashita, H., Suzuki, A., Fukao, K., Nakauchi, H., and Taniguchi, H. (2002). Evidence for hepatocyte differentiation from embryonic stem cells in vitro. Cell Transplant. 11, 429-434.
23. Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W., and Roder, J.C. (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
24. Okita, K., Ichisaka, T., and Yamanaka, S. (2007). Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317.
25. Sharma, A.D., Cantz, T., Vogel, A., Schambach, A., Haridass, D., Iken, M., Bleidissel, M., Manns, M.P., Schöler, H.R., and Ott, M. (2008). Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation. Cell Transplant. 17, 313-323.
26. Stice, S.L. and Robl, J.M. (1988). Nuclear reprogramming in nuclear transplant rabbit embryos. Biol. Reprod. 39, 657-664.
27. Surani, M.A. (2001). Reprogramming of genome function through epigenetic inheritance. Nature 414, 122-128.
28. Tada, M., Tada, T., Lefebvre, L., Barton, S.C., and Surani, M.A. (1997). Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J. 16, 6510-6520.
29. Tada, M., Takahama, Y., Abe, K., Nakatsuji, N., and Tada, T. (2001). Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr. Biol. 11, 1553-1558.
30. Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
31. Taranger, C.K., Noer, A., Sorensen, A.L., Hakelien, A.M., Boquest, A.C., and Collas, P. (2005). Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Mol. Biol. Cell 16, 5719-5735.
32. Terada, N., Hamazaki, T., Oka, M., Hoki, M., Mastalerz, D.M., Nakano, Y., Meyer, E.M., Morel, L., Petersen, B.E., and Scott, E.W. (2002). Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416, 542-545.
33. Teratani, T., Yamamoto, H., Aoyagi, K., Sasaki, H., Asari, A., Quinn, G., Sasaki, H., Terada, M., and Ochiya, T. (2005). Direct hepatic fate specification from mouse embryonic stem cells. Hepatology 41, 836-846.
34. Wernig, M., Meissner, A., Foreman, R., Brambrink, T., Ku, M., Hochedlinger, K., Bernstein, B.E., and Jaenisch, R. (2007). In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448, 318-324.
35. Yamada, T., Yoshikawa, M., Kanda, S., Kato, Y., Nakajima, Y., Ishizaka, S., and Tsunoda, Y. (2002). In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine green. Stem Cells 20, 146-154.
36. +, ESC-derived cells engraft and differentiate into hepatocytes in vivo. Stem Cells 20, 338-346.
37. Ying, Q.L., Nichols, J., Evans, E.P., and Smith, A.G. (2002). Changing potency by spontaneous fusion. Nature 416, 545-548.