Synthesis of some new 1,2,3,4-tetrahydropyrimidine-2-thiones and their thiazolo[3,2-α]pyrimidine derivatives as potential biological agents

Phosphorus, Sulfur and Silicon and the Related Elements

Volumn 183, Issue 8, 2008, Pages 1911-1922

  Akbari, J D ^a   Kachhadia, P K ^a   Tala, S D ^a   Bapodra, A H ^a   Dhaduk, M F ^a   Joshi, H S ^a   Mehta, K B ^a   Pathak, S J ^a  

^a SAURASHTRA UNIVERSITY   (India)

Author keywords

1,2,3,4 Tetrahydropyrimidine 2 thiones; Antimicrobial activity; Spectral analysis; Synthesis; Thiazolo 3,2 pyrimidines

Indexed keywords

EID: 49149088631     PISSN: 10426507     EISSN: 15635325     Source Type: Journal    
DOI: 10.1080/10426500701796330     Document Type: Article

References (28)

1. R. Vitolina and A. Kimenis, Khim.-Farm. Zh., 23, 285 (1989).
2. V. V. Kastron, R. Vitolina, E. L. Khanina, G. Duburs, A. Kimenis, N. V. Kondratenko, V. I. Popov, L. M. Yagupolskii, and A. A. Kolomeitsev, U.S. Patent, 4738965 (1988); Chem. Abstr., 110, 18547h (1989).
3. H. Cho, M. Ueda, K. Shima, A. Mizuno, M. Hayashimatsu, Y. Ohnaka, Y. Takeuchi, M. Hamaguchi, K. Aisaka, T. Hidaka, M. Kawai, M. Takeda, T. Ishihara, K. Funahashi, F. Satoh, M. Morita, and T. Noguchi,J. Med. Chem., 32, 2399 (1989).
4. G. C. Rovynak, K. S. Atwal, A. Hedberg, S. D. Kimball, S. Moreland, J. Z. Gougoutas, B. C. O'Reilly, J. Schwartz, and M. F. Malley, J. Med. Chem., 35, 3254 (1992).
5. M. Ertan, A. Balkan, S. Sarac, S. Uma, J. F. Renaudand, and Y. Rolland, Arch. Pharm., (Weinheim), 324, 135 (1991).
6. M. Ertan, A. Balkan, S. Sarac, S. Uma, K. Rubseman, and J. F. Renaud, Arzneim.-Forsch.:Drug Res., 41, 725 (1991).
7. A. Balkan, M. Ertan, and T. Burgemeister, Arch. Pharm., (Weinheim) 325, 499 (1992).
8. A. Balkan, S. Uma, M. Ertan, and W. Wiegrebe, Pharmazie, 47, 687 (1992).
9. A. Balkan, B. Tozkoparan, M. Ertan, Y. Sara, and N. Ertekin, Boll. Chim. Farm., 135, 648 (1996).
10. G. Doria, C. Passarotti, R. Sala, R. Magrini, P. Sberze, M. Tibolla, R. Ceserani, G. Arcari, R. Castello, and D. Toti, Il Farmaco-Ed. Sc., 40, 885 (1985).
11. E. Jeanneau-Nicolle, M. Benoit-Guyod, A. Namil, and G. Leclerc, Eur. J. Med. Chem., 27, 115 (1992).
12. B. Tozkoparan, M. Ertan, P. Kelicen, and R. Demirdamar, Il Farmaco, 54, 588 (1999).
13. J. Baetz (Seperic), British Patent, GB 1334628 (1973); Chem. Abst., 80, 48028u (1974).
14. B. Dash, M. Patra, and P. K. Mohapatra, J. Inst. Chem., 52, 92 (1980);
15. Chem. Abstr., 93, 239353z (1980).
16. Teijin Ltd., Japanese Patent, Jpn. Kokai Tokkyo Koho JP, 58 24590 [83 24590] (1983).; Chem. Abstr., 98, 215611j (1983).
17. D. Bigg (Synthelabo S.A.), French patent, Fr. Demande FR, 2479831 (1981); Chem. Abstr., 96, 162725z (1982).
18. J. Mohan, V. K. Chadha, H. S. Chaudhary, B. D. Sharma, and H. K. Pujari, Indian J. Exp. Biol., 10, 37 (1972).
19. S. N. Dehuri and A. Nayak, J. Ind. Chem. Soc., 60, 970 (1983).
20. H. R. Champaneri, S. R. Modi, and H. B. Naik, Studies on pyrimidines. Asian J. Chem., 6, 737 (1994);
21. Chem. Abstr. 121, 300842y (1994).
22. C. O Kappe and P. Roschger, J. Heterocycl. Chem., 26, 55 (1989).
23. A. Balkan, M. Ertan, and T. Burgemeister. Arch. Pharm.(Weinheim), 325, 499 (1992).
24. (a) A. Mobinikhaledi, N. Foroughifar, and F. Goodarzi. Phosphorus, Sulfur, and Silicon Relat. Elem., 179, 507 (2004);
25. (b) A. Mobinikhaledi, N. Foroughifar, and B. Ahmadi, Phosphorus, Sulfur, and Silicon Relat. Elem., 180, 339 (2005).
26. (a) P. Biginelli, Gazz. Chim. Ital., 23, 360 (1893);
27. (b) C. O. Kappe and S. F. Falsone, Synlett., 718 (1998), and references therein.
28. A. Kocabalkanli, O. Ates, and G. Otuk, Arch. Pharm. Pharm. Med. Chem., 334, 35 (2001).