New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

Bollettino Chimico Farmaceutico

Volumn 135, Issue 11, 1996, Pages 648-652

  Balkan, A ^b   Tozkoparan, B ^a   Ertan, M ^a   Sara, Y ^a   Ertekin, N ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b Dept of Pharmacology ^*

Author keywords

Calcium antagonistic activities; Syntheis; Thiazolo 3,2 a pyrimidines

Indexed keywords

CALCIUM ANTAGONIST; NIFEDIPINE; THIAZOLO[3,2 A]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; GUINEA PIG; ILEUM; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SMOOTH MUSCLE CONTRACTION;

ANIMALS; CALCIUM CHANNEL BLOCKERS; FEMALE; GUINEA PIGS; ILEUM; MALE; NIFEDIPINE; PYRIMIDINES; THIAZOLES;

EID: 0030390606     PISSN: 00066648     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Doria G., Passorotti C., Sala R., Magrini R., Sberze P., Tibolla M., Cesarini R., Arcari G., Castello R., Toti D., Il Pharmaco-Ed Sci., 40, 885; 1985.
2. Fahre J.L., Farge D., James C., Fr.Pat. 2, 574, 408; 1986, Chem Abstracts 107, 39845g; 1986.
3. Bell S.C., Wei P.H.L., J. Med. Chem., 19, 524; 1976.
4. Di Braccio M., Roma G., Mazzei M., Balbi A., Testa R., II Pharmaco-Ed.Sci., 41(3), 183; 1986.
5. Jap. Pat.. 58 24, 590; 1983, Chem Abstracts 98, 215611j; 1983.
6. Neth. Appl 76 00, 885; 1976, Chem Abstracts 87, 85046p; 1977.
7. Baetz J., Br. Pat. 1, 334, 628; 1973, Chem Abstracts 80, 48028u; 1974.
8. Jeanneau-Nicoll E., Benoit-Guyod M., Namil A., Leclerc G., Eur. J. Med. Chem., 27, 115; 1992.
9. Balkan A., Uma S., Ertan M., Wiegrebe W., Pharmazie, 47, 687; 1992.
10. Ertan M., Balkan A., Saraç S., Uma S., Renaud J.F., Rolland Y., Arch. Pharm. (Weinheim), 324, 135; 1991.
11. Godfraind T., Kaba A., J. Pharmacology, 36, 549; 1969.
12. Takamizawa A., Hirai K., Ishiba T., Matsumoto Y., Chem. Pharm. Bull., 15 (6), 731; 1967.
13. Balkan A., Ertan M., Burgemeister T., Arch. Pharm. (Weinheim), 325, 499; 1992.
14. Kappe C.O., Roschger P., J. Heterocyclic Chem, 26, 55; 1989.