High resolution localized two-dimensional MR spectroscopy in mouse brain in vivo

Magnetic Resonance in Medicine

Volumn 60, Issue 2, 2008, Pages 449-456

  Braakman, Niels ^a   Oerther, Thomas ^b   De Groot, Huub J M ^a   Alia, A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b BRUKER BIOSPIN GMBH   (Germany)

Author keywords

L COSY; Mouse brain; Resonance assignment; Two dimensional MRS

Indexed keywords

BIOMOLECULES; CHEMICAL DETECTION; CHEMICAL SHIFT; MAGNETIC RESONANCE SPECTROSCOPY;

CHEMICAL SHIFT ASSIGNMENT; HIGH FIELD STRENGTHS; IMPROVED SPECTRAL RESOLUTIONS; L-COSY; MOUSE BRAIN; NEUROLOGICAL DISORDERS; PROTON CHEMICAL SHIFTS; RESONANCE ASSIGNMENTS;

METABOLITES;

BIOLOGICAL MARKER;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; BRAIN METABOLISM; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHANTOM;

EID: 49049121222     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21662     Document Type: Article

References (22)

1. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Tang-Wai DF, O'Brien PC, Weigand SD, Edland SD, Smith GE, Ivnik RJ, Ferman TJ, Tangalos EG, Jack CR. 1H MR spectroscopy in common dementias. Neurology 2004;63:1393-1398.
2. Mandal PK. Magnetic resonance spectroscopy (MRS) and its application in Alzheimer's disease. Cone Magn Reson A 2007;30A:40-64.
3. Marjanska M, Curran GL, Wengenack TM, Henry PG, Bliss RL, Poduslo JF, Jack CR Jr, Ugurbil K, Garwood M. Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy. Proc Natl Acad Sci U S A 2005;102:11906-11910.
4. Choi J-K, Dedeoglu A, Jenkins BG. Application of MRS to mouse models of neurodegenerative illness. NMR Biomed 2007;20:216-237.
5. Meric P, Autret G, Doan BT, Gillet B, Sebrie C, Beloeil JC. In vivo 2D magnetic resonance spectroscopy of small animals. MAGMA 2004;17:317-338.
6. Delmas F, Beloeil JC, van der Sanden BPJ, Nicolay K, Gillet B. Two-voxel localization sequence for in vivo two-dimensional homonuclear correlation spectroscopy. J Magn Reson 2001;149:119-125.
7. Welch JWR, Bhakoo K, Dixon RM, Styles P, Sibson NR, Blamire AM. In vivo monitoring of rat brain metabolites during vigabatrin treatment using localized 2D-COSY. NMR Biomed 2003;16:47-54.
8. Peres M, Fedeli O, Barrere B, Gillet B, Berenger G, Seylaz J, Beloeil J-C. In vivo identification and monitoring of changes in rat brain glucose by two-dimensional shift correlated NMR spectroscopy. Magn Reson Med 1992;27:356-361.
9. Thomas MA, Ryner LN, Mehta MP, Turski PA, Sorenson JA. Localized 2D J-resolved 1H MR spectroscopy of human brain. J Magn Reson Imaging 1996;6:453-459.
10. Thomas MA, Yue K, Binesh N, Davanzo P, Kumar A, Siegel B, Frye M, Curran J, Lufkin R, Martin P, Guze B. Localized two-dimensional shift correlated MR spectroscopy of human brain. Magn Reson Med 2001;46:58-67.
11. Ziegler A, Gillet B, Beloeil J, Macher J, Decorps M, Nedelec J. Localized 2D correlation spectroscopy in human brain at 3T. MAGMA 2001;14:45-49.
12. Thomas MA, Hattori N, Umeda M, Sawada T, Naruse S. Evaluation of two-dimensional L-COSY and PRESS using a 3 T MRI scanner: from phantoms to human brain in vivo. NMR Biomed 2003;16:245-251.
13. Von Kienlin M, Ziegler A, Le Fur Y, Rubin C, Decorps M, Remy C. 2D-spatial/2D-spectral spectroscopic imaging of intracerebral gliomas in rat brain. Magn Reson Med 2000;43:211-219.
14. Braakman N, Matysik J, van Duinen SG, Verbeek F, Schliebs R, de Groot HJM, Alia A. Longitudinal assessment of Alzheimer's beta-amyloid plaque development in transgenic mice monitored by in vivo magnetic resonance microimaging. J Magn Reson Imaging 2006;24:530-536.
15. Bottomley PA. Spatial localization in NMR spectroscopy in vivo. Ann N Y Acad Sci 1987;508:333-348.
16. Tkac I, Starcuk Z, Choi IY, Gruetter R. In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn Reson Med 1999;41:649-656.
17. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000;13:129-153.
18. Pfeuffer J, Tkac I, Provencher SW, Gruetter R. Toward an in vivo neurochemical profile: quantification of 18 metabolites in short echo-time 1H NMR spectra of the rat brain. J Magn Reson 1999;141:104-120.
19. van Zijl PCM, Barker PB. Magnetic resonance spectroscopy and spectroscopic imaging for the study of brain metabolism. Ann N Y Acad Sci 1997;820:75-96.
20. Tkac I, Henry PG, Andersen P, Keene CD, Low WC, Gruetter R. Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T. Magn Reson Med 2004;52:478-484.
21. Behar KL, Ogino T. Characterization of macromolecule resonances in the 1H-NMR spectrum of rat brain. Magn Reson Med 1993;30:38-44.
22. Edden RA, Pomper MG, Barker PB. In vivo differentiation of N-acetyl aspartyl glutamate from N-acetyl aspartate at 3 Tesla. Magn Reson Med 2007;57:977-982.