Amino acid substitutions in the structural or nonstructural proteins of a vaccine strain of equine arteritis virus are associated with its attenuation

Virology

Volumn 378, Issue 2, 2008, Pages 355-362

  Zhang, Jianqiang ^a   Go, Yun Young ^a   MacLachlan, N James ^b   Meade, Barry J ^a   Timoney, Peter J ^a   Balasuriya, Udeni B R ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Attenuation; Equine arteritis virus; Infectious clone; Reverse genetics; Structural and nonstructural proteins; Vaccine

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; STRUCTURAL PROTEIN; VIRUS VACCINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CELL CULTURE; EQUINE VIRAL ARTERITIS VIRUS; PHENOTYPE; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, VIRAL; ARTERITIS VIRUS, EQUINE; ARTERIVIRUS INFECTIONS; BODY TEMPERATURE; HORSE DISEASES; HORSES; LEUKOCYTES; LYMPHOCYTE COUNT; MOLECULAR SEQUENCE DATA; NASAL CAVITY; NEUTRALIZATION TESTS; PLAQUE ASSAY; RECOMBINATION, GENETIC; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; VACCINES, ATTENUATED; VIRAL NONSTRUCTURAL PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRAL VACCINES;

EQUIDAE; EQUINE ARTERITIS VIRUS;

EID: 49049119255     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.06.003     Document Type: Article

References (49)

1. Balasuriya U.B., Snijder E.J., Heidner H.W., Zhang J., Zevenhoven-Dobbe J.C., Boone J.D., McCollum W.H., Timoney P.J., and MacLachlan N.J. Development and characterization of an infectious cDNA clone of the virulent Bucyrus strain of equine arteritis virus. J. Gen. Virol. 88 Pt 3 (2007) 918-924
2. Balasuriya U.B., Snijder E.J., van Dinten L.C., Heidner H.W., Wilson W.D., Hedges J.F., Hullinger P.J., and MacLachlan N.J. Equine arteritis virus derived from an infectious cDNA clone is attenuated and genetically stable in infected stallions. Virology 260 1 (1999) 201-208
3. Beasley D.W., Davis C.T., Whiteman M., Granwehr B., Kinney R.M., and Barrett A.D. Molecular determinants of virulence of West Nile virus in North America. Arch. Virol. Suppl. 18 (2004) 35-41
4. Beasley D.W., Whiteman M.C., Zhang S., Huang C.Y., Schneider B.S., Smith D.R., Gromowski G.D., Higgs S., Kinney R.M., and Barrett A.D. Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains. J. Virol. 79 13 (2005) 8339-8347
5. Cavanagh D. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 142 3 (1997) 629-633
6. Davis C.T., Beasley D.W., Guzman H., Siirin M., Parsons R.E., Tesh R.B., and Barrett A.D. Emergence of attenuated West Nile virus variants in Texas, 2003. Virology 330 1 (2004) 342-350
7. Davis N.L., Powell N., Greenwald G.F., Willis L.V., Johnson B.J., Smith J.F., and Johnston R.E. Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA clone. Virology 183 1 (1991) 20-31
8. Doll E.R., Bryans J.T., McCollum W.H., and Crowe M.E. Isolation of a filterable agent causing arteritis of horses and abortion by mares; its differentiation from the equine abortion (influenza) virus. Cornell Vet. 47 1 (1957) 3-41
9. Doll E.R., Bryans J.T., Wilson J.C., and McCollum W.H. Immunization against equine viral arteritis using modified live virus propagated in cell cultures of rabbit kidney. Cornell Vet. 48 4 (1968) 497-524
10. Doll E.R., Knappenberger R.E., and Bryans J.T. An outbreak of abortion caused by the equine arteritis virus. Cornell Vet. 47 1 (1957) 69-75
11. Flint S.J., Enquist L.W., Racaniello V.R., and Skalka A.M. Prevention and control of viral diseases. Principles of Virology. Second ed. (2004), ASM Press, Washington D.C. 702-755
12. Glaser A.L., Chirnside E.D., Horzinek M.C., and de Vries A.A. Equine arteritis virus. Theriogenology 47 6 (1997) 1275-1295
13. Harry T.O., and McCollum W.H. Stability of viability and immunizing potency of lyophilized, modified equine arteritis live-virus vaccine. Am. J. Vet. Res. 42 9 (1981) 1501-1505
14. Hedges J.F., Demaula C.D., Moore B.D., McLaughlin B.E., Simon S.I., and MacLachlan N.J. Characterization of equine E-selectin. Immunology 103 4 (2001) 498-504
15. Huntington P.J., Forman A.J., and Ellis P.M. The occurrence of equine arteritis virus in Australia. Aust. Vet. J 67 12 (1990) 432-435
16. Johnson B.J., Kinney R.M., Kost C.L., and Trent D.W. Molecular determinants of alphavirus neurovirulence: nucleotide and deduced protein sequence changes during attenuation of Venezuelan equine encephalitis virus. J. Gen. Virol. 67 Pt 9 (1986) 1951-1960
17. Johnston R.E., and Smith J.F. Selection for accelerated penetration in cell culture coselects for attenuated mutants of Venezuelan equine encephalitis virus. Virology 162 2 (1988) 437-443
18. Kinney R.M., Chang G.J., Tsuchiya K.R., Sneider J.M., Roehrig J.T., Woodward T.M., and Trent D.W. Attenuation of Venezuelan equine encephalitis virus strain TC-83 is encoded by the 5′-noncoding region and the E2 envelope glycoprotein. J. Virol. 67 3 (1993) 1269-1277
19. MacLachlan N.J., Balasuriya U.B., Rossitto P.V., Hullinger P.A., Patton J.F., and Wilson W.D. Fatal experimental equine arteritis virus infection of a pregnant mare: immunohistochemical staining of viral antigens. J Vet Diagn Invest 8 3 (1996) 367-374
20. McCollum W.H. Development of a modified virus strain and vaccine for equine viral arteritis. J. Am. Vet. Med. Assoc. 155 2 (1969) 318-322
21. McCollum W.H. Vaccination for equine viral arteritis. In: Bryans J.T., and Gerber H. (Eds). Proceedings of the Second International Conference on Equine Infectious Diseases (1970) 143-151 Paris 1969. S. Karger, Basel
22. McCollum W.H. Pathologic features of horses given avirulent equine arteritis virus intramuscularly. Am. J. Vet. Res. 42 7 (1981) 1218-1220
23. McCollum W.H. Responses of horses vaccinated with avirulent modified-live equine arteritis virus propagated in the E. Derm (NBL-6) cell line to nasal inoculation with virulent virus. Am. J. Vet. Res. 47 9 (1986) 1931-1934
24. McCollum W.H., and Bryans J.T. Serological identification of infection by equine arteritis virus in horses of several countries. In: Bryans J.T., and Gerber H. (Eds). Proceedings of the 3rd International Conference on Equine Infectious Diseases. Paris, 1972 (1973) 256-263
25. McCollum W.H., Doll E.R., and Wilson J.C. The recovery of virus from horses with experimental cases of equine arteritis using monolayer cell cultures of rabbit kidney. Am. J. Vet. Res. 23 (1961) 465-469
26. McCollum W.H., Doll E.R., Wilson J.C., and Cheatham J. Isolation and propagation of equine arteritis virus in monolayer cell cultures of rabbit kidney. Cornell Vet. 52 (1962) 452-458
27. McCollum W.H., Doll E.R., Wilson J.C., and Johnson C.B. Propagation of equine arteritis virus in monolayer cultures of equine kidney. Am. J. Vet. Res. 22 (1961) 731-735
28. McCollum W.H., and Swerczek T.W. Studies of an epizootic of equine viral arteritis in race horses. J. Equine. Med. and Surg. 2 (1978) 293-299
29. McCollum W.H., and Timoney P.J. Experimental observation on the virulence of isolates of equine arteritis virus. In: Wernery U., Wade J.F., Mumford J.A., and Kaaden O.R. (Eds). Proceedings of the 8th International Conference on Equine Infectious Diseases, Dubai, United Arab Emirates, 1998 (1999) 558-559
30. McCollum W.H., Timoney P.J., Lee J.J.W., Habacker P.L., Balasuriya U.B.R., and MacLachlan N.J. Features of an outbreak of equine viral arteritis on a breeding farm associated with abortion and fatal interstitial pneumonia in neonatal foals. In: Wernery U., Wade J.F., Mumford J.A., and Kaaden O.R. (Eds). Proceedings of the 8th International Conference on Equine Infectious Diseases, Dubai, United Arab Emirates, 1998 (1999) 559-560
31. McCollum W.H., Timoney P.J., and Tengelsen L.A. Clinical, virological and serological responses of donkeys to intranasal inoculation with the KY-84 strain of equine arteritis virus. J. Comp. Pathol. 112 2 (1995) 207-211
32. McKinnon A.O., Colbern G.T., Collins J.K., Bowen R.A., Voss J.L., and Umphenour N.W. Vaccination of stallions with a modified live equine viral arteritis virus. J. Equine Vet. Sci. 6 (1986) 66-69
33. Moore B.D., Balasuriya U.B., Hedges J.F., and MacLachlan N.J. Growth characteristics of a highly virulent, a moderately virulent, and an avirulent strain of equine arteritis virus in primary equine endothelial cells are predictive of their virulence to horses. Virology 298 1 (2002) 39-44
34. Moore B.D., Balasuriya U.B., Nurton J.P., McCollum W.H., Timoney P.J., Guthrie A.J., and MacLachlan N.J. Differentiation of strains of equine arteritis virus of differing virulence to horses by growth in equine endothelial cells. Am. J. Vet. Res. 64 6 (2003) 779-784
35. Moraillon A., and Moraillon R. Results of an epidemiological investigation on viral arteritis in France and some other European and African countries. Ann. Rech. Vet. 9 1 (1978) 43-54
36. Murphy T.W., Timoney P.J., and McCollum W.H. Analysis of genetic variation among strains of equine arteritis virus. In: Powell D.G. (Ed). Proceedings of the Fifth International Conference on Equine Infectious Diseases, Lexington, KY 1987 (1988) 3-12
37. Patton J.F., Balasuriya U.B., Hedges J.F., Schweidler T.M., Hullinger P.J., and MacLachlan N.J. Phylogenetic characterization of a highly attenuated strain of equine arteritis virus from the semen of a persistently infected standardbred stallion. Arch. Virol. 144 4 (1999) 817-827
38. Senne D.A., Pearson J.E., and Carbrey E.A. Equine viral arteritis: a standard procedure for the virus neutralization test and comparison of results of a proficiency test performed at five laboratories. Proceedings of the 89th Annual Meeting of the United States Animal Health Association, Milwaukee, WI (1985) 29-34
39. Snijder E.J., and Meulenberg J.J. The molecular biology of arteriviruses. J. Gen. Virol. 79 Pt 5 (1998) 961-979
40. Snijder E.J., and Spaan W.J. Arteriviruses. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology. 5th Ed. (2006), Lippincott Williams & Wilkins, Philadelphia 1337-1355
41. Snijder E.J., van Tol H., Pedersen K.W., Raamsman M.J., and de Vries A.A. Identification of a novel structural protein of arteriviruses. J. Virol. 73 8 (1999) 6335-6345
42. Timoney P., Fallon L., Shuck K., McCollum W., Zhang J., and Williams N. The outcome of vaccinating five pregnant mares with a commercial equine viral arteritis vaccine. Equine Vet. Educ. 19 (2007) 606-611
43. Timoney P.J., and McCollum W.H. Equine viral arteritis. Vet. Clin. North Am. Equine Pract. 9 2 (1993) 295-309
44. Timoney P.J., Umphenour N.W., and McCollum W.H. Safety evaluation of a commercial modified live equine arteritis virus vaccine for use in stallions. In: Powell D.G. (Ed). Proceedings of the fifth International Conference on Equine Infectious Diseases (1988) 19-27 Lexington, KY 1987
45. van Aken D., Zevenhoven-Dobbe J., Gorbalenya A.E., and Snijder E.J. Proteolytic maturation of replicase polyprotein pp1a by the nsp4 main proteinase is essential for equine arteritis virus replication and includes internal cleavage of nsp7. J. Gen. Virol. 87 Pt 12 (2006) 3473-3482
46. Wang Y., Liang Y., Han J., Burkhart K.M., Vaughn E.M., Roof M.B., and Faaberg K.S. Attenuation of porcine reproductive and respiratory syndrome virus strain MN184 using chimeric construction with vaccine sequence. Virology 371 2 (2008) 418-429
47. White L.J., Wang J.G., Davis N.L., and Johnston R.E. Role of alpha/beta interferon in Venezuelan equine encephalitis virus pathogenesis: effect of an attenuating mutation in the 5¢ untranslated region. J. Virol. 75 8 (2001) 3706-3718
48. Wicker J.A., Whiteman M.C., Beasley D.W., Davis C.T., Zhang S., Schneider B.S., Higgs S., Kinney R.M., and Barrett A.D. A single amino acid substitution in the central portion of the West Nile virus NS4B protein confers a highly attenuated phenotype in mice. Virology 349 2 (2006) 245-253
49. Ziebuhr J., Snijder E.J., and Gorbalenya A.E. Virus-encoded proteinases and proteolytic processing in the Nidovirales. J. Gen. Virol. 81 Pt 4 (2000) 853-879