Equine arteritis virus derived from an infectious cDNA clone is attenuated and genetically stable in infected stallions

Virology

Volumn 260, Issue 1, 1999, Pages 201-208

  Balasuriya, Udeni B R ^a   Snijder, Eric J ^b   Van Dinten, Leonie C ^b   Heidner, Hans W ^c   Wilson, W David ^a   Hedges, Jodi F ^a   Hullinger, Pamela J ^d   MacLachlan, N James ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^d CALIFORNIA DEPARTMENT OF FOOD AND AGRICULTURE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; EQUINE VIRAL ARTERITIS VIRUS; GENETIC STABILITY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS VIRULENCE;

EID: 0033587540     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9817     Document Type: Article

References (38)

1. Balasuriya U. B. R., Hedges J. F., Timoney P. J., McCollum W. H., MacLachlan N. J. Genetic stability of equine arteritis virus during horizontal and vertical transmission in an outbreak of equine viral arteritis. J. Gen. Virol. 1999.
2. L) of equine arteritis virus. Virology. 207:1995a;518-527.
3. L envelope glycoprotein. Virology. 232:1997;114-128.
4. L envelope glycoprotein. Virology. 214:1995b;690-697.
5. Boyer J.-C., Haenni A.-L. Infectious transcripts and cDNA clones of RNA viruses. Virology. 198:1994;415-426.
6. Cavanagh D. Nidovirales: A new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 142:1997;629-633.
7. den Boon J. A., Snijder E. J., Chirnside E. D., de Vries A. A. F., Horzinek M. C., Spaan W. J. M. Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily. J. Virol. 65:1991;2910-2920.
8. Doll E. R., Bryans J. T., McCollum W. H., Crowe M. E. W. Isolation of a filterable agent causing arteritis of horses and abortion by mares. Its differentiation from the equine abortion (influenza) virus. Cornell Vet. 47:1957;3-41.
9. Domingo E., Martinez-Salas E., Sobrino F., de la Torre J. C., Portela A., Ortin J., Lopez-Galindez C., Perez-Brena P., Villanueva N., Najera R. The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: Biological relevance - a review. Gene. 40:1985;1-8.
10. Glaser A. L., Chirnside E. D., Horzinek M. C., de Vries A. A. F. Equine arteritis virus. Theriogenology. 47:1997;1275-1295.
11. Glaser A. L., Rottier P. J. M., Horzinek M. C., Colenbrander B. Equine arteritis virus: A review of clinical features and management aspects. Vet. Quart. 18:1996;95-99.
12. Hedges J. F., Balasuriya U. B. R., Timoney P. J., McCollum W. H., MacLachlan N. J. Genetic variation in open reading frame 2 of field isolates and laboratory strains of equine arteritis virus. Virus Res. 42:1996;41-52.
13. Hedges J. F., Balasuriya U. B. R., Timoney P. J., McCollum W. H., MacLachlan N. J. Genetic divergence with emergence of phenotypic variants of equine arteritis virus during persistent infection of stallions. J. Virol. 73:1999;3672-3681.
14. MacLachlan N. J., Balasuriya U. B. R., Rossitto P. V., Hullinger P. J., Patton J. F., Wilson W. D. Fatal experimental equine arteritis virus infection of a pregnant mare: Immunohistochemical staining of viral antigens. J. Vet. Diagn. Invest. 8:1996;367-374.
15. McCollum W. H. Vaccination for Equine Viral Arteritis. Bryans J. T., Gerber H. Proceedings of the 2nd International Conference on Equine Infectious Diseases, Paris 1969. 1970;143-151 S. Karger, Basel.
16. McCollum W. H. Pathologic features of horses given avirulent equine arteritis virus intramuscularly. Am. J. Vet. Res. 42:1981;1218-1220.
17. McCollum W. H., Bryans J. T. Serological identification of infection by equine arteritis virus in horses of several countries. Bryans J. T., Gerber H. Proceedings of the 3rd International Conference on Equine Infectious Diseases, Paris 1972. 1973;256-263 S. Karger, Basel.
18. McCollum W. H., Prickett M. E., Bryans J. T. Temporal distribution of equine arteritis virus in respiratory mucosa, tissues and body fluids of horses infected by inhalation. Res. Vet. Sci. 12:1971;459-464.
19. McCollum W. H., Swerczek T. W. Studies of an epizootic of equine viral arteritis in race horses. J. Equine Med.Surg. 2:1978;293-299.
20. McCollum W. H., Timoney P. J. The pathogenic qualities of the 1984 strain of equine arteritis virus. Proceedings of the Grayson Foundation International Conference of Thoroughbred Breeders Organizations, Ireland 1984. 1984;34-84.
21. McCollum, W. H, and, Timoney, P. J. In press, Experimental observation on the virulence of isolates of equine arteritis virus, Proc.Eighth Intl. Conf. Equine Infect. Dis. Dubai, United Arab Emirates.
22. McCollum, W. H, Timoney, P. J, Lee, J. W. Jr, Habacker, P. L, Balasuriya, U. B. R, and, MacLachlan, N. J. In press, Features of an outbreak of equine viral arteritis on a breeding farm associated with abortion and fatal interstitial pneumonia in neonatal foals, Proc. Eighth Intl. Conf. Equine Infect. Dis. Dubai, United Arab Emirates.
23. McCollum W. H., Timoney P. J., Tengelsen L. A. Clinical, virological and serological responses of donkeys to intranasal inoculation with the KY-84 strain of equine arteritis virus. J. Comp. Pathol. 112:1995;207-211.
24. Meulenberg J. J. M., Bos-DE Ruijter J. N. A., Van De Graaf R., Wensvoort G., Moormann R. J. M. Infectious transcripts from cloned genome-length cDNA of porcinne reproductive and respiratory syndrome virus. J. Virol. 72:1998;380-387.
25. Meyers G., Thiel H.-J., Rumenapf T. Classical swine fever virus: Recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic defective interfering particles. J. Virol. 70:1996;1588-1595.
26. Patton J. F., Balasuriya U. B. R., Hedges J. F., Schweidler T. M., Hullinger P. J., MacLachlan N. J. Phylogenetic characterization of a highly attenuated strain of equine arteritis virus from the semen of a persistently infected standardbred stallion. Arch. Virol. 144:1999;817-827.
27. Racaniello V. R., Baltimore D. Cloned poliovirus complementary cDNA is infectious in mammalian cells. Science. 214:1981;916-919.
28. Reed L. J., Muench H. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:1938;493-497.
29. Rice C. M., Levis R., Strauss J. H., Huang H. V. Production of infectious RNA transcripts from sindbis virus cDNA clones: Mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants. J. Virol. 61:1987;3809-3819.
30. Smith D. B., McAllister J., Casino C., Simmonds P. Virus "quasispecies": Making a mountain out of a molehill. J. Gen. Virol. 78:1997;1511-1519.
31. Snijder E. J., Meulenberg J. J. M. The molecular biology of arteriviruses. J. Gen. Virol. 79:1998;961-979.
32. Snijder E. J., van Tol H., Pedersen K. W., Raamsman M. J. B., de Vries A. A. F. Idenitification of a novel structural protein of arteriviruses. J. Virol. 1999.
33. Sumiyoshi H., Hoke C. H., Trent D. W. Infectious Japanese encephalitis virus RNA can be synthesised from in vitro-ligated cDNA templates. J. Virol. 66:1992;5425-5431.
34. Timoney P. J. Clinical, virological, and epidemiological features of the 1984 outbreak of equine viral arteritis in the Thoroughbred population in Kentucky, USA. Proceedings of the Grayson Foundation International Conference of Thoroughbred Breeders Organizations, Ireland 1984. 1984;. p. 24-33.
35. Timoney P. J., McCollum W. H. Equine viral arteritis. Vet. Clin. N. Am. Eq. Pract. 9:1993;295-309.
36. Timoney P. J., McCollum W. H., Murphy T. W., Roberts A. W., Willard J. G., Carswell G. D. The carrier state in equine arteritis virus infection in the stallion with specific emphasis on the venereal mode of virus transmission. J. Reprod. Fertil. Suppl. 35:1987;95-102.
37. van Dinten L. C., den Boon J. A., Wassenaar A. L. M., Spaan W. J. M., Snijder E. J. An infectious arterivirus cDNA clone: Identification of a replicase point mutation that abolishes discontinuous mRNA transcription. Proc. Natl. Acad. Sci. USA. 94:1997;991-996.
38. van Dinten L. C., Wassenaar A. L. M., Spaan W. J. M., Snijder E. J. Proteolytic processing of the equine arteritis virus replicase ORF1b protein: Identification of cleavage products containing the putative viral polymerase and helicase domains. J. Virol. 70:1996;6625-6633.