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Volumn 391, Issue 8, 2008, Pages 2949-2955

A multivariate approach for the simultaneous determination of losartan potassium and hydrochlorothiazide in a combined pharmaceutical tablet formulation

(3) Maggio, Rubén M a Castellano, Patricia M a Kaufman, Teodoro S a

a Universidad Nacional de Rosario (Argentina)

Author keywords

Chemometric method; Dissolution profiles; Drug content; Hydrochlorothiazide; Losartan potassium; Simultaneous determination

Indexed keywords

CONCENTRATION (PROCESS); CURVE FITTING; DECISION MAKING; DRUG PRODUCTS; LEAST SQUARES APPROXIMATIONS; MULTIVARIANT ANALYSIS; RANDOM VARIABLES; REGRESSION ANALYSIS;

CHEMOMETRIC METHOD; CONCENTRATION RANGES; DISSOLUTION PROFILES; DRUG CONTENT; HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUM; MULTI-VARIATE ANALYSIS; PARTIAL LEAST SQUARES; PHARMACEUTICAL TABLETS; SAMPLE PRE-TREATMENT; SIMULTANEOUS DETERMINATION; SIMULTANEOUS DETERMINATIONS; SPECTRAL DATA;

POTASSIUM;

DRUG; HYDROCHLOROTHIAZIDE; LOSARTAN; POTASSIUM;

ARTICLE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; MULTIVARIATE ANALYSIS; STANDARD; TABLET;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROCHLOROTHIAZIDE; LOSARTAN; MULTIVARIATE ANALYSIS; PHARMACEUTICAL PREPARATIONS; POTASSIUM; TABLETS;

EID: 49049103332 PISSN: 16182642 EISSN: 16182650 Source Type: Journal
DOI: 10.1007/s00216-008-2180-z Document Type: Article

Times cited : (35)

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