Emphasis on cell turnover in two hosts infected by bovine leukemia virus: A rationale for host susceptibility to disease

Veterinary Immunology and Immunopathology

Volumn 125, Issue 1-2, 2008, Pages 1-7

  Florins, Arnaud ^a,b   Boxus, Mathieu ^a,b   Vandermeers, Fabian ^a,b   Verlaeten, Olivier ^a,b   Bouzar, Amel Baya ^a,b   Defoiche, Julien ^a,b   Hubaux, Roland ^a,b   Burny, Arsène ^a,b   Kettmann, Richard ^a,b   Willems, Luc ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b FUND FOR SCIENTIFIC RESEARCH   (Belgium)

Author keywords

BLV; Cattle; Cell dynamics; Lymphocyte; Sheep

Indexed keywords

PROTEIN P53;

APOPTOSIS; B LYMPHOCYTE; BOVINE LEUKEMIA VIRUS; CATTLE; CELL FUNCTION; CELL KINETICS; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSFORMATION; DISEASE COURSE; GENE MUTATION; HOST SUSCEPTIBILITY; LEUKEMIA; LEUKEMOGENESIS; LYMPHOID TISSUE; LYMPHOMA; NONHUMAN; REVIEW; SHEEP; VIRUS LOAD; VIRUS TRANSMISSION;

ANIMALS; B-LYMPHOCYTES; CATTLE; ENZOOTIC BOVINE LEUKOSIS; GENES, P53; LEUKEMIA VIRUS, BOVINE; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; SHEEP; SHEEP DISEASES;

BOS; BOVINE LEUKEMIA VIRUS; DELTARETROVIRUS; OVIS ARIES;

EID: 49049093589     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2008.04.007     Document Type: Review

References (31)

1. Asquith B., Debacq C., Florins A., Gillet N., Sanchez-Alcaraz T., Mosley A., and Willems L. Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE). Proc. Biol. Sci. 273 (2006) 1165-1171
2. Asquith B., Debacq C., Macallan D.C., Willems L., and Bangham C.R. Lymphocyte kinetics: the interpretation of labelling data. Trends Immunol. 23 (2002) 596-601
3. Burny A., Bruck C., Cleuter Y., Couez D., Deschamps J., Ghysdael J., Gregoire D., Kettmann R., Mammerickx M., and Marbaix G. Bovine leukemia virus, a versatile agent with various pathogenic effects in various animal species. Cancer Res. 45 (1985) 4578s-4582s
4. Chevallier N., Berthelemy M., Le Rhun D., Laine V., Levy D., and Schwartz-Cornil I. Bovine leukemia virus-induced lymphocytosis and increased cell survival mainly involve the CD11b+B-lymphocyte subset in sheep. J. Virol. 72 (1998) 4413-4420
5. Debacq C., Asquith B., Kerkhofs P., Portetelle D., Burny A., Kettmann R., and Willems L. Increased cell proliferation, but not reduced cell death, induces lymphocytosis in bovine leukemia virus-infected sheep. Proc. Natl. Acad. Sci. U.S.A 99 (2002) 10048-10053
6. Debacq C., Asquith B., Reichert M., Burny A., Kettmann R., and Willems L. Reduced cell turnover in bovine leukemia virus-infected, persistently lymphocytotic cattle. J. Virol. 77 (2003) 13073-13083
7. Debacq C., Gillet N., Asquith B., Sanchez-Alcaraz M.T., Florins A., Boxus M., Schwartz-Cornil I., Bonneau M., Jean G., Kerkhofs P., Hay J., Thewis A., Kettmann R., and Willems L. Peripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheep. J. Virol. 80 (2006) 9710-9719
8. Dees C., Godfrey V.L., Foster J.S., Schultz R.D., and Travis C.C. Stabilization of the p53 gene product in two bovine leukemia virus infected cell lines. Cancer Lett. 86 (1994) 33-40
9. Dees C., Godfrey V.L., Schultz R.D., and Travis C.C. Wild type p53 reduces the size of tumors caused by bovine leukemia virus-infected cells. Cancer Lett. 101 (1996) 115-122
10. Dequiedt F., Hanon E., Kerkhofs P., Pastoret P.P., Portetelle D., Burny A., Kettmann R., and Willems L. Both wild-type and strongly attenuated bovine leukemia viruses protect peripheral blood mononuclear cells from apoptosis. J. Virol. 71 (1997) 630-639
11. Dequiedt F., Kettmann R., Burny A., and Willems L. Mutations in the p53 tumor-suppressor gene are frequently associated with bovine leukemia virus-induced leukemogenesis in cattle but not in sheep. Virology 209 (1995) 676-683
12. Ferrer J.F., Marshak R.R., Abt D.A., and Kenyon S.J. Relationship between lymphosarcoma and persistent lymphocytosis in cattle: a review. J. Am. Vet. Med. Assoc. 175 (1979) 705-708
13. Florins A., Gillet N., Asquith B., Debacq C., Jean G., Schwartz-Cornil I., Bonneau M., Burny A., Reichert M., Kettmann R., and Willems L. Spleen-dependent turnover of CD11b peripheral blood B lymphocytes in bovine leukemia virus-infected sheep. J. Virol. 80 (2006) 11998-12008
14. Florins A., Gillet N., Boxus M., Kerkhofs P., Kettmann R., and Willems L. Even BLV attenuated proviruses can be pathogenic in sheep. J. Virol. 81 (2007) 10195-10200
15. Fulton Jr. B.E., Portella M., and Radke K. Dissemination of bovine leukemia virus-infected cells from a newly infected sheep lymph node. J. Virol. 80 (2006) 7873-7884
16. Gillet N., Florins A., Boxus M., Burteau C., Nigro A., Vandermeers F., Balon H., Bouzar A.B., Defoiche J., Burny A., Reichert M., Kettmann R., and Willems L. Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human. Retrovirology 4 (2007) 18
17. Hein W.R., and Griebel P.J. A road less travelled: large animal models in immunological research. Nat. Rev. Immunol. 3 (2003) 79-84
18. Hellerstein M.K. Measurement of T-cell kinetics: recent methodologic advances. Immunol. Today 20 (1999) 438-441
19. Hopkins S.G., and DiGiacomo R.F. Natural transmission of bovine leukemia virus in dairy and beef cattle. Vet. Clin. North Am. Food Anim. Pract. 13 (1997) 107-128
20. Ishiguro N., Furuoka H., Matsui T., Horiuchi M., Shinagawa M., Asahina M., and Okada K. p53 mutation as a potential cellular factor for tumor development in enzootic bovine leukosis. Vet. Immunol. Immunopathol. 55 (1997) 351-358
21. Komori H., Ishiguro N., Horiuchi M., Shinagawa M., and Aida Y. Predominant p53 mutations in enzootic bovine leukemic cell lines. Vet. Immunol. Immunopathol. 52 (1996) 53-63
22. Levy D., Kettmann R., Marchand P., Djilali S., and Parodi A.L. Selective tropism of bovine leukemia virus (BLV) for surface immunoglobulin-bearing ovine B lymphocytes. Leukemia 1 (1987) 463-465
23. Mammerickx M., Palm R., Portetelle D., and Burny A. Experimental transmission of enzootic bovine leukosis to sheep: latency period of the tumoral disease. Leukemia 2 (1988) 103-107
24. Mammerickx M., Portetelle D., de Clercq K., and Burny A. Experimental transmission of enzootic bovine leukosis to cattle, sheep and goats: infectious doses of blood and incubation period of the disease. Leuk. Res. 11 (1987) 353-358
25. Mirsky M.L., Olmstead C.A., Da Y., and Lewin H.A. The prevalence of proviral bovine leukemia virus in peripheral blood mononuclear cells at two subclinical stages of infection. J. Virol. 70 (1996) 2178-2183
26. Ott S.L., Johnson R., and Wells S.J. Association between bovine-leukosis virus seroprevalence and herd-level productivity on US dairy farms. Prev. Vet. Med. 61 (2003) 249-262
27. Ristevski B., Young A.J., Dudler L., Cahill R.N., Kimpton W., Washington E., and Hay J.B. Tracking dendritic cells: use of an in situ method to label all blood leukocytes. Int. Immunol. 15 (2003) 159-165
28. Tajima S., Zhuang W.Z., Kato M.V., Okada K., Ikawa Y., and Aida Y. Function and conformation of wild-type p53 protein are influenced by mutations in bovine leukemia virus-induced B-cell lymphosarcoma. Virology 243 (1998) 735-746
29. Willems L., Kerkhofs P., Dequiedt F., Portetelle D., Mammerickx M., Burny A., and Kettmann R. Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 11532-11536
30. Young A.J. The physiology of lymphocyte migration through the single lymph node in vivo. Semin. Immunol. 11 (1999) 73-83
31. Zhuang W., Tajima S., Okada K., Ikawa Y., and Aida Y. Point mutation of p53 tumor suppressor gene in bovine leukemia virus-induced lymphosarcoma. Leukemia 11 Suppl. 3 (1997) 344-346