Posttraumatic GABAA-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons

Journal of Neuroscience

Volumn 28, Issue 27, 2008, Pages 6996-7005

  Shulga, Anastasia ^a   Thomas Crusells, Judith ^a   Sigl, Thomas ^c   Blaesse, Anne ^a   Mestres, Pedro ^c   Meyer, Michael ^d   Yan, Qiao ^e   Kaila, Kai ^b   Saarma, Mart ^a   Rivera, Claudio ^a   Giehl, Klaus M ^c,f  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c SAARLAND UNIVERSITY   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e AMGEN INC   (United States)

^f OHIO STATE UNIVERSITY   (United States)

Author keywords

Chloride homeostasis; Intracellular Ca2+; KCC2; Neuronal survival; NKCC1; Trophic factors

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM; CHLORIDE; NEUROTROPHIN; POTASSIUM; SODIUM; 4 AMINOBUTYRIC ACID; BUMETANIDE; COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM-CHLORIDE SYMPORTERS; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1 PROTEIN; SODIUM-POTASSIUM-CHLORIDE COTRANSPORTER 1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL MATURATION; CELL POPULATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; UPREGULATION; ANIMAL; BRAIN INJURY; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; DRUG ANTAGONISM; DRUG EFFECT; MALE; METABOLISM; NERVE CELL; NERVE CELL INHIBITION; NERVE FIBER; NERVE REGENERATION; NEWBORN; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; AXONS; AXOTOMY; BRAIN INJURIES; BRAIN-DERIVED NEUROTROPHIC FACTOR; BUMETANIDE; CALCIUM SIGNALING; CELL SURVIVAL; CHLORIDES; DOWN-REGULATION; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; MALE; MEMBRANE POTENTIALS; MICE; NERVE REGENERATION; NEURAL INHIBITION; NEURONS; ORGAN CULTURE TECHNIQUES; PYRAMIDAL TRACTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; SYMPORTERS;

EID: 49049093088     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5268-07.2008     Document Type: Article

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