Anticonvulsant impact of lesions in the ventrolateral forebrain of rats challenged with soman

Brain Research

Volumn 1226, Issue , 2008, Pages 241-247

  Myhrer, Trond ^a   Enger, Siri ^a   Aas, Pål ^a  

^a NORWEGIAN DEFENCE RESEARCH ESTABLISHMENT FFI   (Norway)

Author keywords

Anticonvulsant effect; Convulsion; Lesion; Soman

Indexed keywords

METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; PROTEIN C FOS; SOMAN;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; CONVULSION; ENTORHINAL CORTEX; EPILEPSY; FOREBRAIN; HIPPOCAMPUS; KINDLING; MALE; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN MAPPING; DISEASE MODELS, ANIMAL; MALE; PROSENCEPHALON; RATS; RATS, WISTAR; REACTION TIME; SEIZURES; SOMAN;

RATTUS;

EID: 48849084493     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.06.014     Document Type: Article

References (30)

1. Browning R.A., and Nelson D.K. Modification of electroshock and pentylenetetrazol seizure patterns in rats after precollicular transections. Exp. Neurol. 93 (1986) 546-556
2. Carpentier P., Lambrinidis M., and Blanchet G. Early dendritic changes in hippocampal pyramidal neurones (field CA1) of rats subjected to acute soman intoxication; a light microscopic study. Brain Res. 541 (1991) 293-299
3. Denoyer M., Lallement G., Collet A., Pernot-Marino I., Séréno D., and Blanchet G. Influence of medial septal cholinoceptive cells on c-Fos-like proteins induced by soman. Brain Res. 592 (1992) 157-162
4. Ebert U., and Löscher W. Strong induction of c-fos in the piriform cortex during focal seizures evoked from different limbic sites. Brain Res. 671 (1995) 334-338
5. Ekstrand J.J., Domroese M.E., Johnson D.M.G., Feig S.L., Knodel S.M., Behan M., and Maberly L.B. A new subdivision of anterior piriform cortex and associated deep nucleus with novel features of interest for olfaction and epilepsy. J. Comp. Neurol. 434 (2001) 289-307
6. Gale K. Progression and generalization of seizure discharge: anatomical and neurochemical substrates. Epilepsia 29 Suppl. 2 (1988) S15-S34
7. Halonen T., Tortorella A., Zrebeet H., and Gale K. Posterior piriform and perirhinal cortex relay seizures evoked from the area tempestas; role of excitatory and inhibitory amino acid receptors. Brain Res. 652 (1994) 145-148
8. Kelly M.E., Staines W.A., and McIntyre D.C. Secondary generalization of hippocampal kindled seizures: examination of the role of the piriform cortex. Brain Res. 957 (2002) 152-161
9. Lallement G., Denoyer M., Collet A., Pernot-Marino I., Baubichon D., Monmaur P., and Blanchet G. Changes in hippocampal acetylcholine and glutamate extracellular levels during soman-induced seizures; influence of septal cholinoceptive cells. Neurosci. Lett. 139 (1992) 104-107
10. Löscher W., and Ebert U. Basic mechanisms of seizure propagation: targets for rational drug design and rational polypharmacy. Epilepsy. Res. 11 Suppl. (1996) 17-43
11. McDonough Jr. J.H., and Shih T.M. Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology. Neurosci. Biobehav. Rev. 21 (1997) 559-579
12. McDonough Jr. J.H., McLeod Jr. C.G., and Nipwoda T. Direct microinjection of soman or VX into the amygdala produces repetitive limbic convulsions and neuropathology. Brain Res. 435 (1987) 123-137
13. McDonough Jr. J.H., Dochterman W., Smith C.D., and Shih T.M. Protection against nerve agent-induced neuropathology, but not cardiac pathology, is associated with the anticonvulsant action of drug treatment. Neurotoxicology 15 (1995) 123-132
14. McIntyre D.C., and Kelly M.E. The parahippocampal cortices and kindling. Ann. N. Y. Acad. Sci. 911 (2000) 343-354
15. McIntyre D.C., Kelly M.E., and Armstrong J.N. Kindling in the perirhinal cortex. Brain. Res. 615 (1993) 1-6
16. McIntyre D.C., Kelly M.E., and Staines W.A. Efferent projections of the anterior perirhinal cortex in the rat. J. Comp. Neurol. 369 (1996) 302-318
17. Myhrer T. Effects of selective perirhinal and postrhinal lesions on acquisition and retention of a visual discrimination task in rats. Neurobiol. Learn. Mem. 73 (2000) 68-78
18. Myhrer T. Neuronal structures involved in the induction and propagation of seizures caused by nerve agents: implications for medical treatment. Toxicology 239 (2007) 1-14
19. Myhrer T., Enger S., and Aas P. Anticonvulsant effects of damage to structures involved in seizure induction in rats exposed to soman. Neurotoxicology 28 (2007) 819-828
20. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1982), Academic Press, Sidney
21. Racine R.J., Paxinos G., Mosher J.M., and Kairiss E.W. The effects of various lesions and knife-cuts on septal and amygdala kindling in the rat. Brain Res. 454 (1988) 264-274
22. Schmued L.C., and Hopkins K.J. Flouro-Jade B; a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 874 (2000) 123-130
23. Schmued L.C., Albertson C., and Slikker Jr. W. Fluoro-Jade; a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751 (1997) 37-46
24. Sterri S.H., Lyngaas S., and Fonnum F. Toxicity of soman after repetitive injection of sublethal doses in rats. Acta. Pharmacol. Toxicol. 46 (1980) 1-7
25. Swinyard E. Assay of antiepileptic drug activity in experimental animals: standard tests. In: Mercier J. (Ed). Anticonvulsant Drugs (1973), Pergamon Press, Oxford 47-65
26. Taylor P. Anticholinesterase agents. In: Hardman J.G., Limbird L.E., and Gilman A.G. (Eds). The Pharmacological Basis of Therapeutics (2001), McGraw-Hill Companies, Inc., New York 175-191
27. Tortorella A., Halonen T., Sahibzada N., and Gale K. A crucial role of the amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype of glutamate receptors in piriform and perirhinal cortex for the initiation and propagation of limbic motor seizures. J. Pharmacol. Exp. Therap. 280 (1997) 1401-1405
28. Williams A.J., Berti R., Yao C., Price R.A., Velarde L.C., Koplovitz I., Schultz S.M., Tortella F.C., and Dave J.R. Central neuro-inflammatory gene response following soman exposure in the rat. Neurosci. Lett. 349 (2003) 147-150
29. Wolf N.J., Eckenstein F., and Butcher L.L. Cholinergic systems in the rat brain: I. Projections to the limbic telencephalon. Brain. Res. Bull. 13 (1984) 751-784
30. Zimmer L.A., Ennis M., Wiley R.G., and Shipley M.T. Nerve gas-induced seizures: role of acetylcholine in the rapid inductions of Fos and glial fibrillary acidic protein in piriform cortex. J. Neurosci. 15 (1998) 3897-3908