메뉴 건너뛰기




Volumn 19, Issue 6, 2008, Pages 2642-2649

Mitochondrial protein import motor: Differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CARRIER PROTEIN; CHAPERONE; HEAT SHOCK PROTEIN 70; MITOCHONDRIAL PROTEIN; PRESEQUENCE TRANSLOCASE ASSOCIATED MOTOR 16; PRESEQUENCE TRANSLOCASE ASSOCIATED MOTOR 17; PRESEQUENCE TRANSLOCASE ASSOCIATED MOTOR 18; TRANSLOCASE OF INNER MEMBRANE 23; TRANSLOCASE OF INNER MEMBRANE 44; UNCLASSIFIED DRUG;

EID: 48749118288     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E07-12-1226     Document Type: Article
Times cited : (53)

References (49)
  • 2
    • 34249897492 scopus 로고    scopus 로고
    • A dynamic machinery for import of precursor proteins
    • Bohnert, M., Pfanner, N., and van der Laan, M. (2007). A dynamic machinery for import of precursor proteins. FEBS Lett. 581, 2802-2810.
    • (2007) FEBS Lett , vol.581 , pp. 2802-2810
    • Bohnert, M.1    Pfanner, N.2    van der Laan, M.3
  • 3
    • 33646127577 scopus 로고    scopus 로고
    • Molecular chaperones and protein quality control
    • Bukau, B., Weissman, J., and Horwich, A. (2006). Molecular chaperones and protein quality control. Cell 125, 443-451.
    • (2006) Cell , vol.125 , pp. 443-451
    • Bukau, B.1    Weissman, J.2    Horwich, A.3
  • 4
    • 0142105410 scopus 로고    scopus 로고
    • Mitochondrial translocation contact sites: Separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex
    • Chacinska, A., Rehling, P., Guiard, B., Frazier, A. E., Schulze-Specking, A., Pfanner, N., Voos, W., and Meisinger, C. (2003). Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22, 5370-5381.
    • (2003) EMBO J , vol.22 , pp. 5370-5381
    • Chacinska, A.1    Rehling, P.2    Guiard, B.3    Frazier, A.E.4    Schulze-Specking, A.5    Pfanner, N.6    Voos, W.7    Meisinger, C.8
  • 5
    • 20244373481 scopus 로고    scopus 로고
    • Mitochondrial presequence translocase: Switching between TOM tethering and motor recruitment involves Tim21 and Tim17
    • Chacinska, A. et al. (2005). Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120, 817-829.
    • (2005) Cell , vol.120 , pp. 817-829
    • Chacinska, A.1
  • 6
    • 0031918163 scopus 로고    scopus 로고
    • Strong precursor-pore interactions constrain models for mitochondrial protein import
    • Chauwin, J. F., Oster, G., and Glick, B. S. (1998). Strong precursor-pore interactions constrain models for mitochondrial protein import. Biophys J. 74, 1732-1743.
    • (1998) Biophys J , vol.74 , pp. 1732-1743
    • Chauwin, J.F.1    Oster, G.2    Glick, B.S.3
  • 7
    • 0030845840 scopus 로고    scopus 로고
    • The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44
    • Dekker, P. J., Martin, F., Maarse, A. C., Bömer, U., Müller, H., Guiard, B., Meijer, M., Rassow, J., and Pfanner, N. (1997). The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44. EMBO J. 16, 5408-5419.
    • (1997) EMBO J , vol.16 , pp. 5408-5419
    • Dekker, P.J.1    Martin, F.2    Maarse, A.C.3    Bömer, U.4    Müller, H.5    Guiard, B.6    Meijer, M.7    Rassow, J.8    Pfanner, N.9
  • 8
    • 33746575844 scopus 로고    scopus 로고
    • Evolution of the molecular machines for protein import into mitochondria
    • Dolezal, P., Likic, V., Tachezy, J., and Lithgow, T. (2006). Evolution of the molecular machines for protein import into mitochondria. Science 313, 314-318.
    • (2006) Science , vol.313 , pp. 314-318
    • Dolezal, P.1    Likic, V.2    Tachezy, J.3    Lithgow, T.4
  • 9
    • 0345133332 scopus 로고    scopus 로고
    • D'Silva, P. D., Schilke, B., Walter, W., Andrew, A., and Craig, E. A. (2003). J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix. Proc. Natl. Acad. Sci. USA 100, 13839-13844.
    • D'Silva, P. D., Schilke, B., Walter, W., Andrew, A., and Craig, E. A. (2003). J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix. Proc. Natl. Acad. Sci. USA 100, 13839-13844.
  • 10
    • 24644486039 scopus 로고    scopus 로고
    • D'Silva, P. R., Schilke, B., Walter, W., and Craig, E. A. (2005). Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane. Proc. Natl. Acad. Sci. USA 102, 12419-12424.
    • D'Silva, P. R., Schilke, B., Walter, W., and Craig, E. A. (2005). Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane. Proc. Natl. Acad. Sci. USA 102, 12419-12424.
  • 11
    • 38749083424 scopus 로고    scopus 로고
    • Interaction of the J-protein heterodimer, Pam18/Pam16, of the mitochondrial import motor with the translocon of the inner membrane
    • D'Silva, P. R., Schilke, B., Hayashi, M., and Craig, E. A. (2008). Interaction of the J-protein heterodimer, Pam18/Pam16, of the mitochondrial import motor with the translocon of the inner membrane. Mol. Biol. Cell 19, 424-432.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 424-432
    • D'Silva, P.R.1    Schilke, B.2    Hayashi, M.3    Craig, E.A.4
  • 12
    • 77956688584 scopus 로고    scopus 로고
    • Dudek, J., Guiard, B., and Rehling, P. (2007). The role of the TIM23 complex and its associated motor complex in mitochondrial protein import. In: The Enzymes. Molecular Machines Involved in Protein Transport across Cellular Membranes, ed. R. E. Dalbey, C. M. Koehler, and F. Tamanoi, London: Elsevier Academic Press, 387-411.
    • Dudek, J., Guiard, B., and Rehling, P. (2007). The role of the TIM23 complex and its associated motor complex in mitochondrial protein import. In: The Enzymes. Molecular Machines Involved in Protein Transport across Cellular Membranes, ed. R. E. Dalbey, C. M. Koehler, and F. Tamanoi, London: Elsevier Academic Press, 387-411.
  • 13
    • 0042386354 scopus 로고    scopus 로고
    • Functional cooperation and separation of translocators in protein import into mitochondria, the double-membrane bounded organelle
    • Endo, T., Yamamoto, H., and Esaki, M. (2003). Functional cooperation and separation of translocators in protein import into mitochondria, the double-membrane bounded organelle. J. Cell Sci. 116, 3259-3267.
    • (2003) J. Cell Sci , vol.116 , pp. 3259-3267
    • Endo, T.1    Yamamoto, H.2    Esaki, M.3
  • 14
    • 0142059893 scopus 로고    scopus 로고
    • Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space
    • Frazier, A. E., Chacinska, A., Truscott, K. N., Guiard, B., Pfanner, N., and Rehling, P. (2003). Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol. Cell. Biol. 23, 7818-7828.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 7818-7828
    • Frazier, A.E.1    Chacinska, A.2    Truscott, K.N.3    Guiard, B.4    Pfanner, N.5    Rehling, P.6
  • 15
    • 10744229056 scopus 로고    scopus 로고
    • Pam16 has an essential role in the mitochondrial protein import motor
    • Frazier, A. E. et al. (2004). Pam16 has an essential role in the mitochondrial protein import motor. Nat. Struct. Mol. Biol. 11, 226-233.
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 226-233
    • Frazier, A.E.1
  • 19
    • 0036221085 scopus 로고    scopus 로고
    • Protein unfolding by the mitochondrial membrane potential
    • Huang, S., Ratliff, K. S., and Matouschek, A. (2002). Protein unfolding by the mitochondrial membrane potential. Nat. Struct. Biol. 9, 301-307.
    • (2002) Nat. Struct. Biol , vol.9 , pp. 301-307
    • Huang, S.1    Ratliff, K.S.2    Matouschek, A.3
  • 20
    • 0035190881 scopus 로고    scopus 로고
    • Opening the door to mitochondrial protein import
    • Jensen, R. E., and Johnson, A. E. (2001). Opening the door to mitochondrial protein import. Nat. Struct. Biol. 8, 1008-1010.
    • (2001) Nat. Struct. Biol , vol.8 , pp. 1008-1010
    • Jensen, R.E.1    Johnson, A.E.2
  • 21
    • 7544219638 scopus 로고    scopus 로고
    • New developments in mitochondrial assembly
    • Koehler, C. M. (2004). New developments in mitochondrial assembly. Annu. Rev. Cell Dev. Biol. 20, 309-335.
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 309-335
    • Koehler, C.M.1
  • 22
    • 0026520064 scopus 로고
    • Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space
    • Koll, H., Guiard, B., Rassow, J., Ostermann, J., Horwich, A. L., Neupert, W., and Hartl, F. U. (1992). Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell 68, 1163-1175.
    • (1992) Cell , vol.68 , pp. 1163-1175
    • Koll, H.1    Guiard, B.2    Rassow, J.3    Ostermann, J.4    Horwich, A.L.5    Neupert, W.6    Hartl, F.U.7
  • 24
    • 0028556615 scopus 로고
    • Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane
    • Kronidou, N. G., Oppliger, W., Bolliger, L., Hannavy, K., Glick, B. S., Schatz, G., and Horst, M. (1994). Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane. Proc. Natl. Acad. Sci. USA 91, 12818-12822.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12818-12822
    • Kronidou, N.G.1    Oppliger, W.2    Bolliger, L.3    Hannavy, K.4    Glick, B.S.5    Schatz, G.6    Horst, M.7
  • 25
    • 0002694056 scopus 로고
    • A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction
    • Leung, D. W., Chen, E., and Goeddel, D. V. (1989). A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction. Technique 1, 11-15.
    • (1989) Technique , vol.1 , pp. 11-15
    • Leung, D.W.1    Chen, E.2    Goeddel, D.V.3
  • 26
    • 4444315535 scopus 로고    scopus 로고
    • The presequence translocase-associated protein import motor of mitochondria: Pam16 functions in an antagonistic manner to Pam18
    • Li, Y., Dudek, J., Guiard, B., Pfanner, N., Rehling, P., and Voos, W. (2004). The presequence translocase-associated protein import motor of mitochondria: Pam16 functions in an antagonistic manner to Pam18. J. Biol. Chem. 279, 38047-38054.
    • (2004) J. Biol. Chem , vol.279 , pp. 38047-38054
    • Li, Y.1    Dudek, J.2    Guiard, B.3    Pfanner, N.4    Rehling, P.5    Voos, W.6
  • 27
    • 33744989706 scopus 로고    scopus 로고
    • Tim50 maintains the permeability barrier of the mitochondrial inner membrane
    • Meinecke, M. et al. (2006). Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312, 1523-1526.
    • (2006) Science , vol.312 , pp. 1523-1526
    • Meinecke, M.1
  • 30
    • 0141865519 scopus 로고    scopus 로고
    • Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria
    • Mokranjac, D., Sichting, M., Neupert, W., and Hell, K. (2003b). Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J. 22, 4945-4956.
    • (2003) EMBO J , vol.22 , pp. 4945-4956
    • Mokranjac, D.1    Sichting, M.2    Neupert, W.3    Hell, K.4
  • 31
    • 33749360278 scopus 로고    scopus 로고
    • Mokranjac, D., Bourenkov, G., Hell, K., Neupert, W., and Groll, M. (2006). Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. EMBO J. 25, 4675-4685.
    • Mokranjac, D., Bourenkov, G., Hell, K., Neupert, W., and Groll, M. (2006). Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. EMBO J. 25, 4675-4685.
  • 32
    • 34547117629 scopus 로고    scopus 로고
    • Association of the Tim14-Tim16 subcomplex with the TIM23 translocase is crucial for function of the mitochondrial protein import motor
    • Mokranjac, D., Berg, A., Adam, A., Neupert, W., and Hell, K. (2007). Association of the Tim14-Tim16 subcomplex with the TIM23 translocase is crucial for function of the mitochondrial protein import motor. J. Biol. Chem. 282, 18037-18045.
    • (2007) J. Biol. Chem , vol.282 , pp. 18037-18045
    • Mokranjac, D.1    Berg, A.2    Adam, A.3    Neupert, W.4    Hell, K.5
  • 33
    • 34249873947 scopus 로고    scopus 로고
    • Translocation of proteins into mitochondria
    • Neupert, W., and Herrmann, J. M. (2007). Translocation of proteins into mitochondria. Annu. Rev. Biochem. 76, 723-749.
    • (2007) Annu. Rev. Biochem , vol.76 , pp. 723-749
    • Neupert, W.1    Herrmann, J.M.2
  • 34
    • 17044437776 scopus 로고    scopus 로고
    • A railroad switch in mitochondrial protein import
    • Oka, T., and Mihara, K. (2005). A railroad switch in mitochondrial protein import. Mol. Cell 18, 145-146.
    • (2005) Mol. Cell , vol.18 , pp. 145-146
    • Oka, T.1    Mihara, K.2
  • 35
    • 20144380176 scopus 로고    scopus 로고
    • Protein targeting: Entropy, energetics and modular machines
    • Perry, A. J., and Lithgow, T. (2005). Protein targeting: entropy, energetics and modular machines. Curr. Biol. 15, R423-R425.
    • (2005) Curr. Biol , vol.15
    • Perry, A.J.1    Lithgow, T.2
  • 36
    • 0028046847 scopus 로고
    • Mitochondrial protein import: Biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44
    • Rassow, J., Maarse, A. C., Krainer, E., Kübrich, M., Müller, H., Meijer, M., Craig, E. A., and Pfanner, N. (1994). Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44. J. Cell Biol. 127, 1547-1556.
    • (1994) J. Cell Biol , vol.127 , pp. 1547-1556
    • Rassow, J.1    Maarse, A.C.2    Krainer, E.3    Kübrich, M.4    Müller, H.5    Meijer, M.6    Craig, E.A.7    Pfanner, N.8
  • 38
    • 0024669291 scopus 로고
    • System of shuttle vectors and yeast host strains designated for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and Hieter, P. A. (1989). System of shuttle vectors and yeast host strains designated for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.A.2
  • 39
    • 0026090063 scopus 로고
    • In vitro mutagenesis and plasmid shuffling: From cloned gene to mutant yeast
    • Sikorski, R. S., and Boeke J. D. (1991). In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol. 194, 302-318.
    • (1991) Methods Enzymol , vol.194 , pp. 302-318
    • Sikorski, R.S.1    Boeke, J.D.2
  • 41
    • 10744228445 scopus 로고    scopus 로고
    • A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria
    • Truscott, K. N. et al. (2003). A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J. Cell Biol. 163, 707-713.
    • (2003) J. Cell Biol , vol.163 , pp. 707-713
    • Truscott, K.N.1
  • 43
    • 33750949389 scopus 로고    scopus 로고
    • A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria
    • van der Laan, M., Wiedemann, N., Mick, D. U., Guiard, B., Rehling, P., and Pfanner, N. (2006). A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr. Biol. 16, 2271-2276.
    • (2006) Curr. Biol , vol.16 , pp. 2271-2276
    • van der Laan, M.1    Wiedemann, N.2    Mick, D.U.3    Guiard, B.4    Rehling, P.5    Pfanner, N.6
  • 45
    • 0027362778 scopus 로고
    • Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix
    • Voos, W., Gambill, B. D., Guiard, B., Pfanner, N., and Craig, E. A. (1993). Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J. Cell Biol. 123, 119-126.
    • (1993) J. Cell Biol , vol.123 , pp. 119-126
    • Voos, W.1    Gambill, B.D.2    Guiard, B.3    Pfanner, N.4    Craig, E.A.5
  • 46
    • 4344590764 scopus 로고    scopus 로고
    • The J-protein family: Modulating protein assembly, disassembly and translocation
    • Walsh, P., Bursac, D., Law, Y. C., Cyr, D., and Lithgow, T. (2004). The J-protein family: modulating protein assembly, disassembly and translocation. EMBO Rep. 5, 567-571.
    • (2004) EMBO Rep , vol.5 , pp. 567-571
    • Walsh, P.1    Bursac, D.2    Law, Y.C.3    Cyr, D.4    Lithgow, T.5
  • 47
    • 37249039150 scopus 로고    scopus 로고
    • Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain
    • Wiedemann, N., van der Laan, M., Hutu, D. P., Rehling, P., and Pfanner, N. (2007). Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain. J. Cell Biol. 179, 1115-1122.
    • (2007) J. Cell Biol , vol.179 , pp. 1115-1122
    • Wiedemann, N.1    van der Laan, M.2    Hutu, D.P.3    Rehling, P.4    Pfanner, N.5
  • 48
    • 0037111988 scopus 로고    scopus 로고
    • Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes
    • Yamamoto, H., Esaki, M., Kanamori, T., Tamura, Y., Nishikawa, S., and Endo, T. (2002). Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes. Cell 111, 519-528.
    • (2002) Cell , vol.111 , pp. 519-528
    • Yamamoto, H.1    Esaki, M.2    Kanamori, T.3    Tamura, Y.4    Nishikawa, S.5    Endo, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.