Guanylyl cyclase and protein kinase G mediate nitric oxide suppression of 5-lipoxygenase metabolism in rat alveolar macrophages

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1781, Issue 6-7, 2008, Pages 299-305

  Coffey, Michael J ^a   Phare, Susan M ^a   Luo, Ming ^a   Peters Golden, Marc ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

cGMP; Endotoxin; Leukotrienes; Nitric oxide; Protein kinase G

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 6 ANILINO 5,8 QUINOLINEQUINONE; ARACHIDONATE 5 LIPOXYGENASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANYLATE CYCLASE; KT 5823; NITRIC OXIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME METABOLISM; ENZYME REGULATION; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

AMINOQUINOLINES; ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; CARBAZOLES; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; GUANYLATE CYCLASE; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; NITRIC OXIDE; RATS; SUBCELLULAR FRACTIONS;

RATTUS;

EID: 48749105456     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2008.04.005     Document Type: Article

References (48)

1. Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220 (1983) 568-575
2. Lewis R., and Austen K. The biologically active leukotrienes: biosynthesis, metabolism, receptors, functions, and pharmacology. J. Clin. Invest. 73 (1984) 889-897
3. Dixon R.A.F., Jones R.E., Diehl R.E., Bennett C.D., Kargman S., and Rouzer C.A. Cloning of the cDNA for human 5-lipoxygenase. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 416-420
4. Dixon R.A., Diehl R.E., Opas E., Rands E., Vickers P.J., Evans J.F., Gillard J.W., and Miller D.K. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343 (1990) 282-284
5. Brock T., McNish R., Bailie M., and Peters-Golden M. Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence. J. Biol. Chem. 272 (1997) 8276-8280
6. Rouzer C.A., and Kargman S. Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187. J. Biol. Chem. 263 (1988) 10980-10988
7. Moncada S., Palmer R., and Higgs E. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43 (1991) 109-142
8. Gaston B., Drazen J., Loscalzo J., and Stamler J. The biology of nitrogen oxides in the airways. Am. J. Respir. Crit. Care Med. 149 (1994) 538-551
9. Raychaudhuri B., Dweik R., Connors M., Buhrow L., Malur A., Drazba J., Arroliga A., Erzurum S., Kavura M., and Thomassen M. Nitric oxide blocks nuclear factor-kB activation in alveolar macrophages. Am. J. Resir. Cell Mol. Biol. 21 (1999) 311-316
10. Rovira I. Use of nitric oxide in acute respiratory failure. Clin. Pulm. Med. 6 (1999) 187-194
11. Brunn G., Hey C., Wessler I., and Racke K. Endogenous nitric oxide inhibits leukotriene B4 release from alveolar macrophages. Eur. J. Pharmacol. 326 (1997) 53-60
12. Coffey M., Phare S., and Peters-Golden M. Prolonged exposure to lipopolysaccharide inhibits macrophage 5-lipoxygenase metabolism via induction of nitric oxide synthesis. J. Immunol. 165 (2000) 3592-3598
13. Brock T., McNish R., Mancuso P., Coffey M., and Peters-Golden M. Prolonged lipopolysaccharide inhibits leukotriene synthesis in peritoneal macrophages:mediation by nitric oxide and prostaglandins. Prostaglandins other Lipid Mediat. 71 (2003) 131-145
14. Friebe A., and Koesling D. Regulation of nitric oxide-sensitive guanylyl cyclase. Circ. Res. 93 (2003) 96-105
15. Baranano D., and Snyder S. Neural roles for heme oxygenase: contrasts to nitric oxide synthase. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 10996-11002
16. Schulz S., Wedel B., Matthews A., and Garbers D. The cloning and expression of a new guanylyl cyclase orphan receptor. J. Biol. Chem. 273 (1998) 1032-1037
17. Kiemer A., and Vollmar A. Autocrine regulation of inducible nitric-oxide synthase in macrophages by atrial natriuretic peptide. J. Biol. Chem. 273 (1998) 13444-13451
18. Kuhn M. Structure, regulation, and function of mammalian membrane guanylyl cyclase receptors, with a focus on guanylyl cyclase-A. Circ. Res. 93 (2003) 700-709
19. Pilz R., and Casteel D. Regulation of gene expression by cyclic GMP. Circ. Res. 93 (2003) 1034-1046
20. Salinas D., Sparkman L., Berhane K., and Boggaram V. Nitric oxide inhibits surfactant protein B gene expression in lung epithelial cells. Am. J. Physiol., Lung Cell. Mol. Physiol. 285 (2003) L1153-L1165
21. Coffey M., Peters-Golden M., Fantone J., and Sporn P. Membrane association of active 5-lipoxygenase in resting cells: evidence for novel regulation of the enzyme in the rat alveolar macrophage. J. Biol. Chem. 267 (1992) 570-576
22. Peters-Golden M., McNish R.W., Hyzy R., Shelly C., and Toews G.B. Alterations in the pattern of arachidonate metabolism accompany rat macrophage differentiation in the lung. J. Immunol. 144 (1990) 263-270
23. Coffey M., Wilcoxen S., and Peters-Golden M. Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism which accompanies differentiation of peripheral blood monocytes into alveolar macrophages. Am. J. Resir. Cell Mol. Biol. 11 (1994) 153-158
24. Misko T., Schilling R., Salvemini D., Moore W., and Currie M. A fluoremetric assay for the measurement of nitrite in biological samples. Anal. Biochem. 214 (1993) 11-16
25. Maccarrone M., Corasaniti M., Guerrieri P., Nistico G., and Finazzi Agro A. Nitric oxide-donor compounds inhibit lipoxygenase activity. Biochim. Biophys. Res. Commun. 219 (1996) 128-133
26. Hwang T., Hung H., Kao S., Teng C., Wu C., and Cheng S. Soluble guanylyl cyclase activator YC-1 inhibits human neutrophil functions through a cGMP-independent but cAMP-dependent pathway. Mol. Pharmacol. 64 (2003) 1419-1427
27. Lodygin D., Menssen A., and Hermeking H. Induction of the Cdk inhibitor p21 by LY83583 inhibits tumor cell proliferation in a p53-independent manner. J. Clin. Invest. 110 (2002) 1717-1727
28. Barnstable C., Wei J., and Han M. Modulation of synaptic function by cGMP and cGMP-gated cation channels. Neurochem. Int. 45 (2004) 875-884
29. Feil R., Lohmann S., de Jonge H., Walter U., and Hofmann F. Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice. Circ. Res. 93 (2003) 907-916
30. Healy A., Peters-Golden M., Yao J., and Brock T. Identification of a bipartite nuclear localization sequence necessary for nuclear import of 5-lipoxygenase. J. Biol. Chem. 274 (1999) 29812-29818
31. Gamm D., Francis S., Angelotti T., Corbin J., and Uhler M. The type II isoform of cGMP-dependent protein kinase is dimeric and possesses regulatory and catalytic properties distinct from the type I isoforms. J. Biol. Chem. 270 (1995) 27380-27388
32. Taylor M., Ahmed R., Begley M., and Uhler M. Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase. J. Biol. Chem. 277 (2002) 37242-37253
33. Brock T., McNish R., and Peters-Golden M. Translocation and leukotriene synthetic capacity of nuclear 5-lipoxygenase in rat basophilic leukemia cells and alveolar macrophages. J. Biol. Chem. 270 (1995) 21652-21658
34. Laemmli U. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
35. Coffey M., Phare S., and Peters-Golden M. Induction of inducible nitric oxide synthase by lipopolysaccharide/interferon gamma and sepsis down-regulates 5-lipoxygenase metabolism in murine alveolar macrophages. Exp. Lung Res. 30 (2004) 615-633
36. Zabel U., Kleinschnitz C., Oh P., Nedvetsky P., Smolenski A., Muller H., Kronich P., Kugler P., Walter U., Schnitzer J., and Schmidt H. Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide. Nat. Cell Biol. 4 (2002) 307-311
37. Vaandrager A., Tilly B., Smolenski A., Schneider-Rasp S., Bot A., Edixhoven M., Scholte B., Jarchau T., Walter U., Lohmann S., Poller W., and de Jonge H. cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta. J. Biol. Chem. 272 (1997) 4195-4200
38. Pryzwansky K., Wyatt T., Nichols H., and Lincoln T. Compartmentalization of cyclic GMP-dependent protein kinase in formyl-peptide stimulated neutrophils. Blood 76 (1990) 612-618
39. Taylor M., and Uhler M. The amino-terminal cyclic nucleotide binding site of the type II cGMP-dependent protein kinase is essential for full cyclic nucleotide-dependent activation. J. Biol. Chem. 275 (2000) 28053-28062
40. Pryzwansky K., Kidao S., Wyatt T., Reed W., and Lincoln T. Localization of cyclic GMP-dependent protein kinase in human mononuclear phagocytes. J. Leukoc. Biol. 57 (1995) 670-678
41. Martin II W. Neutrophils kill pulmonary endothelial cells by a hydrogen-peroxide-dependent pathway: an in vitro model of neutrophil-mediated lung injury. Am. Rev. Respir. Dis. 130 (1984) 209
42. Balter M., Eschenbacher W., and Peters-Golden M. Arachidonic acid metabolism in cultured alveolar macrophages from normal, atopic, and asthmatic subjects. Am. Rev. Respir. Dis. 138 (1988) 1134
43. Bolla M., Caruso P., Giossi M., Folco G., Civelli M., and Sala A. Comparative analysis of isolated human bronchi contraction and biosynthesis of cysteinyl leukotrienes using a direct 5-lipoxygenase inhibitor. Biochem. Pharmacol. 54 (1997) 437-442
44. Hamad A., Clayton A., Islam B., and Knox A. Guanylyl cyclases, nitric oxide, natriuretic peptides, and airway smooth muscle function. Am. J. Physiol., Lung Cell. Mol. Physiol. 285 (2003) L973-L983
45. Morris C., Poljakovic M., Lavrisha L., Machado L., Kuypers F., and Morris S.J. Decreased arginine bioavailability and increased serum arginase activity in asthma. Am. J. Respir. Crit. Care Med. 170 (2004) 148-153
46. Donnelly L., and Barnes P. Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells. Am. J. Resir. Cell Mol. Biol. 26 (2002) 144-151
47. Spina D., Ferlenga P., Biasini I., Moriggi E., Marchini F., Semeraro C., and Page C. The effect duration of selective phosphodiesterase inhibitors in the guinea pig. Life Sci. 62 (1998) 953-965
48. Luo M., Jones S., Phare S., Coffey M., Peters-Golden M., and Brock T. Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523. J. Biol. Chem. 279 (2004) 41512-41520