An approach towards method development for untargeted urinary metabolite profiling in metabonomic research using UPLC/QToF MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 871, Issue 2, 2008, Pages 341-348

  Wong, Max C Y ^a   Lee, Warren T K ^a   Wong, Jayme S Y ^a   Frost, Gary ^b   Lodge, John ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Metabonomics; Quality control; Untargeted profiling; UPLC QToF MS; Urine

Indexed keywords

BIOMOLECULES; CLUSTER ANALYSIS; DATA ACQUISITION; FLOW OF SOLIDS; GRADIENT METHODS; METHANOL; QUANTUM CHEMISTRY; QUANTUM THEORY;

CHROMATOGRAPHIC RESOLUTIONS; CYCLE TIME (CT); ELUTION GRADIENT; EXPERIMENTAL CONDITIONS; MASS SHIFT; METABOLIC PROFILING; METABOLITE PROFILING; METHOD DEVELOPMENT; MONITOR (CO); PRE-TREATMENTS; RETENTION TIME (RT); SAMPLE PRE TREATMENT;

METABOLITES;

METHANOL;

ADULT; ARTICLE; DILUTION; ELUTION; FLOW RATE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLOMICS; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINE;

ADULT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPUTATIONAL BIOLOGY; HUMANS; MALE; MASS SPECTROMETRY; METABOLISM; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS; SPECIMEN HANDLING; URINE;

EID: 48749104267     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.06.033     Document Type: Article

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