Spontaneous low-frequency blood oxygenation level-dependent fluctuations and functional connectivity analysis of the 'resting' brain

Magnetic Resonance Imaging

Volumn 26, Issue 7, 2008, Pages 1055-1064

  Auer, Dorothee P ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Functional connectivity; Low frequency fluctuations; Resting state networks; Slow oscillations

Indexed keywords

ANTIDEPRESSANT AGENT; METHYLPHENIDATE; MIDAZOLAM;

ALZHEIMER DISEASE; ANALYTIC METHOD; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; BLOOD OXYGENATION; BLOOD OXYGENATION LEVEL DEPENDENT; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; BRAIN MAPPING; COGNITIVE DEFECT; CONTRAST ENHANCEMENT; CORPUS CALLOSUM AGENESIS; CORRELATION ANALYSIS; DEPRESSION; DIAGNOSTIC IMAGING; ELECTROENCEPHALOGRAM; EPILEPSY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMODYNAMICS; HUMAN; MENTAL DISEASE; MULTIPLE SCLEROSIS; NERVE CELL; NONHUMAN; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; RESPIRATORY FUNCTION; SCHIZOPHRENIA; SENSITIVITY ANALYSIS;

ARTIFACTS; BRAIN; BRAIN DISEASES; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; HUMANS; MAGNETIC RESONANCE IMAGING; OXYGEN; REST;

EID: 48549087974     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2008.05.008     Document Type: Article

References (101)

1. Friston K.J., Frith C.D., Liddle P.F., and Frackowiak R.S. Functional connectivity: the principal-component analysis of large (PET) data sets. J Cereb Blood Flow Metab 13 (1993) 5-14
2. Biswal B., Yetkin F.Z., Haughton V.M., and Hyde J.S. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34 (1995) 537-541
3. De Luca M., Smith S., De Stefano N., Federico A., and Matthews P.M. Blood oxygenation level dependent contrast resting state networks are relevant to functional activity in the neocortical sensorimotor system. Exp Brain Res 167 (2005) 587-594
4. Greicius M.D., Krasnow B., Reiss A.L., and Menon V. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A 100 (2003) 253-258
5. Raichle M.E., MacLeod A.M., Snyder A.Z., Powers W.J., Gusnard D.A., and Shulman G.L. A default mode of brain function. Proc Natl Acad Sci U S A 98 (2001) 676-682
6. Fox M.D., and Raichle M.E. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 8 (2007) 700-711
7. Rogers B.P., Morgan V.L., Newton A.T., and Gore J.C. Assessing functional connectivity in the human brain by fMRI. Magn Reson Imaging 25 10 (2007) 1347-1357
8. Kruger G., and Glover G.H. Physiological noise in oxygenation-sensitive magnetic resonance imaging. Magn Reson Med 46 (2001) 631-637
9. Biswal B.B., Van Kylen J., and Hyde J.S. Simultaneous assessment of flow and BOLD signals in resting-state functional connectivity maps. NMR Biomed 10 (1997) 165-170
10. Triantafyllou C., Hoge R.D., Krueger G., et al. Comparison of physiological noise at 1.5 T, 3 T and 7 T and optimization of fMRI acquisition parameters. NeuroImage 26 (2005) 243-250
11. Lowe M.J., Mock B.J., and Sorenson J.A. Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations. NeuroImage 7 (1998) 119-132
12. Shmueli K., van Gelderen P., de Zwart J.A., et al. Low-frequency fluctuations in the cardiac rate as a source of variance in the resting-state fMRI BOLD signal. NeuroImage 38 (2007) 306-320
13. Birn R.M., Murphy K., and Bandettini P.A. The effect of respiration variations on independent component analysis results of resting state functional connectivity. Hum Brain Mapp (2008)
14. Birn R.M., Diamond J.B., Smith M.A., and Bandettini P.A. Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI. NeuroImage 31 (2006) 1536-1548
15. Wise R.G., Ide K., Poulin M.J., and Tracey I. Resting fluctuations in arterial carbon dioxide induce significant low frequency variations in BOLD signal. NeuroImage 21 (2004) 1652-1664
16. Auer L.M., and Gallhofer B. Rhythmic activity of cat pial vessels in vivo. Eur Neurol 20 (1981) 448-468
17. Xu Y., Wu Z., Wu G., et al. A new fMRI biomarker for hippocampal change with disease progression. Alzheimer's and Dementia 3 (2007) S120
18. Hudetz A.G., Roman R.J., and Harder D.R. Spontaneous flow oscillations in the cerebral cortex during acute changes in mean arterial pressure. J Cereb Blood Flow Metab 12 (1992) 491-499
19. Kirkeby O.J., Rise I.R., and Risoe C. Rhythmical fluctuations of the intracerebral microcirculation studied in pigs. Int J Microcirc Clin Exp 15 (1995) 316-324
20. Clark Jr. L.C., Misrahy G., and Fox R.P. Chronically implanted polarographic electrodes. J Appl Physiol 13 (1958) 85-91
21. Davies P.W., and Bronk D.W. Oxygen tension in mammalian brain. Fed Proc 16 (1957) 689-692
22. Vern B.A., Schuette W.H., Leheta B., Juel V.C., and Radulovacki M. Low-frequency oscillations of cortical oxidative metabolism in waking and sleep. J Cereb Blood Flow Metab 8 (1988) 215-226
23. Mitra P.P., Ogawa S., Hu X., and Ugurbil K. The nature of spatiotemporal changes in cerebral hemodynamics as manifested in functional magnetic resonance imaging. Magn Reson Med 37 (1997) 511-518
24. Mayhew J.E., Askew S., Zheng Y., et al. Cerebral vasomotion: a 0.1-Hz oscillation in reflected light imaging of neural activity. NeuroImage 4 (1996) 183-193
25. Hundley W.G., Renaldo G.J., Levasseur J.E., and Kontos H.A. Vasomotion in cerebral microcirculation of awake rabbits. Am J Physiol 254 (1988) H67-H71
26. Dirnagl U., Lindauer U., and Villringer A. Nitric oxide synthase blockade enhances vasomotion in the cerebral microcirculation of anesthetized rats. Microvasc Res 45 (1993) 318-323
27. Fujii K., Heistad D.D., and Faraci F.M. Vasomotion of basilar arteries in vivo. Am J Physiol 258 (1990) H1829-H1834
28. Biswal B., Hudetz A.G., Yetkin F.Z., Haughton V.M., and Hyde J.S. Hypercapnia reversibly suppresses low-frequency fluctuations in the human motor cortex during rest using echo-planar MRI. J Cereb Blood Flow Metab 17 (1997) 301-308
29. Morita-Tsuzuki Y., Bouskela E., and Hardebo J.E. Vasomotion in the rat cerebral microcirculation recorded by laser-Doppler flowmetry. Acta Physiol Scand 146 (1992) 431-439
30. Peltier S.J., Kerssens C., Hamann S.B., Sebel P.S., Byas-Smith M., and Hu X. Functional connectivity changes with concentration of sevoflurane anesthesia. NeuroReport 16 (2005) 285-288
31. Kiviniemi V.J., Haanpaa H., Kantola J.H., et al. Midazolam sedation increases fluctuation and synchrony of the resting brain BOLD signal. Magn Reson Imaging 23 (2005) 531-537
32. Pelled G., and Goelman G. Different physiological MRI noise between cortical layers. Magn Reson Med 52 (2004) 913-916
33. Quigley M., Cordes D., Turski P., et al. Role of the corpus callosum in functional connectivity. Am J Neuroradiol 24 (2003) 208-212
34. He B.J., Snyder A.Z., Vincent J.L., Epstein A., Shulman G.L., and Corbetta M. Breakdown of functional connectivity in frontoparietal networks underlies behavioral deficits in spatial neglect. Neuron 53 (2007) 905-918
35. Leopold D.A., Murayama Y., and Logothetis N.K. Very slow activity fluctuations in monkey visual cortex: implications for functional brain imaging. Cereb Cortex 13 (2003) 422-433
36. Shmuel A.A.M., Oeltermann A., and Logothetis N.K. Spontaneous fluctuations in functional MRI signal reflect fluctuations in the underlying neuronal activity. NeuroImage (2007) [Proceedings 13th International Conference on Functional Mapping of the Human Brain].
37. Shmuel A., and Leopold D.A. Neuronal correlates of spontaneous fluctuations in fMRI signals in monkey visual cortex: implications for functional connectivity at rest. Hum Brain Mapp (2008)
38. Lu H., Zuo Y., Gu H., et al. Synchronized delta oscillations correlate with the resting-state functional MRI signal. Proc Natl Acad Sci U S A 104 (2007) 18265-18269
39. Moosmann M., Ritter P., Krastel I., et al. Correlates of alpha rhythm in functional magnetic resonance imaging and near infrared spectroscopy. Neuroimage 20 (2003) 145-158
40. Laufs H., Krakow K., Sterzer P., et al. Electroencephalographic signatures of attentional and cognitive default modes in spontaneous brain activity fluctuations at rest. Proc Natl Acad Sci U S A 100 (2003) 11053-11058
41. Goncalves S.I., de Munck J.C., Pouwels P.J., et al. Correlating the alpha rhythm to BOLD using simultaneous EEG/fMRI: inter-subject variability. NeuroImage 30 (2006) 203-213
42. Laufs H., Holt J.L., Elfont R., et al. Where the BOLD signal goes when alpha EEG leaves. Neuroimage 31 (2006) 1408-1418
43. Scheeringa R., Bastiaanse M.C., Petersson K.M., Oostenveld R., Norris D.G., and Hagoort P. Frontal theta EEG activity correlates negatively with the default mode network in resting state. Int J Psychophysio 67 (2008) 242-251
44. Mantini D., Perrucci M.G., Del Gratta C., Romani G.L., and Corbetta M. Electrophysiological signatures of resting state networks in the human brain. Proc Natl Acad Sci U S A 104 (2007) 13170-13175
45. Cordes D., Haughton V.M., Arfanakis K., et al. Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data. Am J Neuroradiol 22 (2001) 1326-1333
46. Wang K., Liang M., Wang L., et al. Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study. Hum Brain Mapp 28 (2007) 967-978
47. Glover G.H., Li T.Q., and Ress D. Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR. Magn Reson Med 44 (2000) 162-167
48. Lund T.E., Madsen K.H., Sidaros K., Luo W.L., and Nichols T.E. Non-white noise in fMRI: does modelling have an impact?. NeuroImage 29 (2006) 54-66
49. Kiviniemi V., Kantola J.H., Jauhiainen J., Hyvarinen A., and Tervonen O. Independent component analysis of nondeterministic fMRI signal sources. NeuroImage 19 (2003) 253-260
50. van de Ven V.G., Formisano E., Prvulovic D., Roeder C.H., and Linden D.E. Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest. Hum Brain Mapp 22 (2004) 165-178
51. Beckmann C.F., DeLuca M., Devlin J.T., and Smith S.M. Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond B Biol Sci 360 (2005) 1001-1013
52. Damoiseaux J.S., Rombouts S.A., Barkhof F., et al. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci U S A 103 (2006) 13848-13853
53. De Luca M., Beckmann C.F., De Stefano N., Matthews P.M., and Smith S.M. fMRI resting state networks define distinct modes of long-distance interactions in the human brain. NeuroImage 29 (2006) 1359-1367
54. Jafri M.J., Pearlson G.D., Stevens M., and Calhoun V.D. A method for functional network connectivity among spatially independent resting-state components in schizophrenia. NeuroImage 39 (2008) 1666-1681
55. Xiong J., Parsons L.M., Gao J.H., and Fox P.T. Interregional connectivity to primary motor cortex revealed using MRI resting state images. Hum Brain Mapp 8 (1999) 151-156
56. Cordes D., Haughton V.M., Arfanakis K., et al. Mapping functionally related regions of brain with functional connectivity MR imaging. Am J Neuroradiol 21 (2000) 1636-1644
57. Hampson M., Peterson B.S., Skudlarski P., Gatenby J.C., and Gore J.C. Detection of functional connectivity using temporal correlations in MR images. Hum Brain Mapp 15 (2002) 247-262
58. Rombouts S.A., Stam C.J., Kuijer J.P., Scheltens P., and Barkhof F. Identifying confounds to increase specificity during a "no task condition". Evidence for hippocampal connectivity using fMRI. NeuroImage 20 (2003) 1236-1245
59. Vincent J.L., Snyder A.Z., Fox M.D., et al. Coherent spontaneous activity identifies a hippocampal-parietal memory network. J Neurophysiol 96 (2006) 3517-3531
60. Fox M.D., Corbetta M., Snyder A.Z., Vincent J.L., and Raichle M.E. Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci U S A 103 (2006) 10046-10051
61. Fox M.D., Snyder A.Z., Vincent J.L., Corbetta M., Van Essen D.C., and Raichle M.E. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A 102 (2005) 9673-9678
62. Fransson P. Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. Hum Brain Mapp 26 (2005) 15-29
63. Vincent J.L., Patel G.H., Fox M.D., et al. Intrinsic functional architecture in the anaesthetized monkey brain. Nature 447 (2007) 83-86
64. Zhao F., Zhao T., Zhou L., Wu Z., and Hu X. BOLD study of stimulation-induced neural activity and resting-state connectivity in medetomidine-sedated rat. NeuroImage 39 1 (2008) 248-260
65. Horovitz S.G., Fukunaga M., de Zwart J.A., et al. Low frequency BOLD fluctuations during resting wakefulness and light sleep: A simultaneous EEG-fMRI study. Hum Brain Mapp (2007)
66. Peltier S.J., LaConte S.M., Niyazov D.M., et al. Reductions in interhemispheric motor cortex functional connectivity after muscle fatigue. Brain Res 1057 (2005) 10-16
67. Fransson P. How default is the default mode of brain function? Further evidence from intrinsic BOLD signal fluctuations. Neuropsychologia 44 (2006) 2836-2845
68. Hampson M., Olson I.R., Leung H.C., Skudlarski P., and Gore J.C. Changes in functional connectivity of human MT/V5 with visual motion input. NeuroReport 15 (2004) 1315-1319
69. Newton A.T., Morgan V.L., and Gore J.C. Task demand modulation of steady-state functional connectivity to primary motor cortex. Hum Brain Mapp 28 (2007) 663-672
70. Stanberry L.I., Richards T.L., Berninger V.W., et al. Low-frequency signal changes reflect differences in functional connectivity between good readers and dyslexics during continuous phoneme mapping. Magn Reson Imaging 24 (2006) 217-229
71. Rao H., Gillihan S.J., Wang J., et al. Genetic variation in serotonin transporter alters resting brain function in healthy individuals. Biol Psychiatry 62 (2007) 600-606
72. Fair D.A., Dosenbach N.U., Church J.A., et al. Development of distinct control networks through segregation and integration. Proc Natl Acad Sci U S A 104 (2007) 13507-13512
73. Damoiseaux J.S., Beckmann C.F., Ariqita E.J., Barkhof F., Scheltens P., Stam C.J., Smith S.M., and Rambouts S.A. Reduced resting state activity in the 'default network' in normal aging. Cereb Cortex (2008) [in press]
74. Li S.J., Li Z., Wu G., Zhang M.J., Franczak M., and Antuono P.G. Alzheimer Disease: evaluation of a functional MR imaging index as a marker. Radiology 225 (2002) 253-259
75. Lowe M.J., Phillips M.D., Lurito J.T., Mattson D., Dzemidzic M., and Mathews V.P. Multiple sclerosis: low-frequency temporal blood oxygen level-dependent fluctuations indicate reduced functional connectivity initial results. Radiology 224 (2002) 184-192
76. Greicius M.D., Srivastava G., Reiss A.L., and Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A 101 (2004) 4637-4642
77. Wang L., Zang Y., He Y., et al. Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. NeuroImage 31 (2006) 496-504
78. Allen G., Barnard H., McColl R., et al. Reduced hippocampal functional connectivity in Alzheimer disease. Arch Neurol 64 (2007) 1482-1487
79. Sorg C., Riedl V., Muhlau M., et al. Selective changes of resting-state networks in individuals at risk for Alzheimer's disease. Proc Natl Acad Sci U S A 104 (2007) 18760-18765
80. Garrity A.G., Pearlson G.D., McKiernan K., Lloyd D., Kiehl K.A., and Calhoun V.D. Aberrant 'default mode' functional connectivity in schizophrenia. Am J Psychiatry 164 (2007) 450-457
81. Liang M., Zhou Y., Jiang T., et al. Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging. NeuroReport 17 (2006) 209-213
82. Liu H., Liu Z., Liang M., et al. Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study. NeuroReport 17 (2006) 19-22
83. Zhou Y., Liang M., Jiang T., et al. Functional dysconnectivity of the dorsolateral prefrontal cortex in first-episode schizophrenia using resting-state fMRI. Neurosci Lett 417 (2007) 297-302
84. Zhou Y., Liang M., Tian L., et al. Functional disintegration in paranoid schizophrenia using resting-state fMRI. Schizophr Res 97 (2007) 194-205
85. Bluhm R.L., Miller J., Lanius R.A., et al. Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenic patients: anomalies in the default network. Schizophr Bull 33 (2007) 1004-1012
86. Jafri M.J., Pearlson G.D., Stevens M., and Calhoun V.D. A method for functional network connectivity among spatially independent resting-state components in schizophrenia. NeuroImage 39 4 (2008) 1666-1681
87. Anand A., Li Y., Wang Y., et al. Antidepressant effect on connectivity of the mood-regulating circuit: an FMRI study. Neuropsychopharmacology 30 (2005) 1334-1344
88. Greicius M.D., Flores B.H., Menon V., et al. Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol Psychiatry 62 (2007) 429-437
89. Tian L., Jiang T., Wang Y., et al. Altered resting-state functional connectivity patterns of anterior cingulate cortex in adolescents with attention deficit hyperactivity disorder. Neurosci Lett 400 (2006) 39-43
90. Castellanos F.X., Margulies D.S., et al. Cingulate precuneus interactions: a new locus of dysfunction in adult attention deficit/hyperactivity disorder. Biol Psychiatry 63 3 (2008) 332-337
91. Zang Y.F., He Y., Zhu C.Z., et al. Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev 29 (2007) 83-91
92. Kennedy D.P., and Courchesne E. The intrinsic functional organization of the brain is altered in autism. NeuroImage 39 4 (2008) 1877-1885
93. Cherkassky V.L., Kana R.K., Keller T.A., and Just M.A. Functional connectivity in a baseline resting-state network in autism. NeuroReport 17 (2006) 1687-1690
94. Gotman J., Kobayashi E., Bagshaw A.P., Benar C.G., and Dubeau F. Combining EEG and fMRI: a multimodal tool for epilepsy research. J Magn Reson Imaging 23 (2006) 906-920
95. Waites A.B., Briellmann R.S., Saling M.M., Abbott D.F., and Jackson G.D. Functional connectivity networks are disrupted in left temporal lobe epilepsy. Ann Neurol 59 (2006) 335-343
96. Quigley M., Cordes D., Wendt G., et al. Effect of focal and nonfocal cerebral lesions on functional connectivity studied with MR imaging. Am J Neuroradiol 22 (2001) 294-300
97. Liu Y., D'Arceuil H., He J., et al. MRI of spontaneous fluctuations after acute cerebral ischemia in nonhuman primates. J Magn Reson Imaging 26 (2007) 1112-1116
98. Anand A., Li Y., Wang Y., et al. Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study. Biol Psychiatry 57 (2005) 1079-1088
99. Li S.J., Biswal B., Li Z., et al. Cocaine administration decreases functional connectivity in human primary visual and motor cortex as detected by functional MRI. Magn Reson Med 43 (2000) 45-51
100. Anderson C.M., Lowen S.B., and Renshaw P.F. Emotional task-dependent low-frequency fluctuations and methylphenidate: wavelet scaling analysis of 1/f-type fluctuations in fMRI of the cerebellar vermis. J Neurosci Methods 151 (2006) 52-61
101. Dashdorj N.A.C., Alexakis C., Hlinka J., Mason R., Siddiqui Q., and Auer D.P. Midazolam sedation disrupts the corticolimbic network connection: an fcMRI study. Proc ISMRM (2008) 93